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 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper describes the prevalence rates of macular drusen in a population of known insulin-dependent diabetic patients. The prevalence rate was found to be higher in the insulin-dependent diabetic than population bases in previous studies. There also is a suggestion that the presence of diabetic retinopathy does not increase the likelihood of macular drusen but that cardiovascular disease and/or hypertension may have a positive effect on the development of macular drusen.
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PMID:The prevalence of macular drusen in a population of patients with known insulin-dependent diabetes mellitus. 387 89

Age related macular degeneration (ARMD) is one of the leading causes of irreversible vision loss in patients over 65 years of age. Nearly 30 percent of persons over 75 years of age will suffer from ARMD. The etiology is not yet fully understood. Besides age, many risk factors such as gender, arterial hypertension, arteriolosclerosis, elevated serum lipids, smoking, alcohol abusus, and exposure to UV light are being discussed. Genetic factors are certainly involved as well; familiar predisposition is assumed in more than 50 percent of cases. White individuals are more affected than colored ones. Predisposing ocular signs are macular drusen, focal hyperpigmentation, and light eyes. In this review, anatomical, pathophysiological and fluorescein-angiographic features and the clinical classification of exudative and dry stages of ARMD are described. Concepts of management of ARMD include pharmacological measures, laser treatment, photodynamic therapy, and surgery including excision of submacular choroidal neovascular membranes and macular translocation. Success rates of any therapeutic method are very limited. Low vision aids are promising by improving quality of life in many cases.
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PMID:[Age-related macular degeneration (AMD)--therapeutic possibilities and new approaches]. 1121 84