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Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Thirty seven patients with arterial hypertension of renal genesis (chronic diffuse glomerulonephritis, chronic pyelonephritis, renal cystic disease and congenital abnormalities) were subjected to NMR-tomography. The comparison group comprised 12 patients with essential hypertension and 18 normal individuals constituted the control group. The examination was effected in the axial, frontal and sagittal planes using the BMT-1100 NMR-tomograph (Brucker, FRG) with the magnetic intensity of 0.235 T, the coil diameter of 60 cm, and the working frequency of 9.95 MHz. The technique made it possible to draw conclusions as to the presence or absence of the kidneys, their form, size, location and the structure of their cortex and medulla. The anatomo-tomographic picture of the kidneys in patients with chronic diffuse glomerulonephritis without renal insufficiency resembled that in cases of essential hypertension. In patients with chronic pyelonephritis the kidney contour was uneven and when renal insufficiency was present the kidneys were small and the borderline the cortex and the medulla was poorly differentiated. The technique proved especially informative in renal cystic disease and congenital abnormalities (renal aplasia and hypoplasia). The results obtained were compared with the data provided by other examination techniques.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1985
PMID:[Diagnostic potentials of NMR tomography of the kidneys of patients with symptomatic renal hypertension]. 406 86

The article reflects the results of five-year secondary and primary prevention of arterial hypertension among the workers of a large automobile plant. Secondary prevention of arterial hypertension is an important means of reducing arterial hypertension complications and mortality (the overall mortality went down by 20%, and brain stroke morbidity was 70% lower in the intervention population than in the comparison one). Besides, the search and implementation of the methods of primary prevention of arterial hypertension constitutes the main perspective of the scientific and practical solution of the problem on the population level, as non-drug intervention normalized arterial blood pressure in 70% of subjects with mild hypertension. Thus, arterial hypertension is a complex medico-social problem, the solution of which depends on the fulfillment of equally important medical and socio-cultural tasks.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1985
PMID:[Possibilities, difficulties and prospects for mass prevention of arterial hypertension]. 406 87

The article contains data on preliminary evaluation of the efficacy of secondary prevention of arterial hypertension among industrial workers of "Avto ZIL" amalgamation. Population studies to reveal major cardiovascular diseases show a certain increase of arterial hypertension and other disease morbidity accompanied by temporary disability. A considerable positive effect is observed in groups of hypertensives undergoing regular and effective anti-hypertension preventive treatment. Long-term regular hypotensive treatment of hypertensive subjects and the lowering of blood pressure to less than 160/90 mm Hg contributes to the decrease in labour and economic losses and to increased labour productivity of industrial workers.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1985
PMID:[Effect of measures for the detection and long-term drug therapy of arterial hypertension on the morbidity and work capacity of industrial workers]. 406 88

A complex study of changes of hemodynamics and myocardial performance was conducted while treating 215 hypertensive patients with obsidan (propranolol), corgard, a cardioselective beta-blocker tenormine and alpha- and beta-blocker trandate. Different hypotensive efficiency and varying hemodynamic mechanisms of its action were found. Obsidan and corgard were mainly efficient in moderate hypertension and marked hypersympathicotonia. Tenormine and trandate produce the most marked hypotensive effect (due to reduction in the vascular tone). The signs of increase in venous blood return to the heart during trandate and obsidan therapy and decrease in venous return after long-term tenormine therapy were established. Myocardial contractility indices decreased after obsidan therapy to the more extent than after corgard and tenormine, and they did not change after trandate. The possibility of myocardial hypertrophy regression was shown (especially in the long-term treatment with tenormine and trandate). A reduction in intramyocardial tension has been stated to depend mainly on hemodynamic factors (reduction in volume or pressure overload on the myocardium) whereas the diminution of the myocardial mass also depends on neurohumoral effects.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1983
PMID:[Comparative evaluation of the therapeutic effect of various classes of beta-blockaders in patients with hypertension]. 613 17

A total of 59 patients aged 16-74 years with arterial hypertension (AH) were examined. The AH duration was from 0.5 to 28 years. In 42 patients AH was stable, 17 patients had the syndrome of malignant AH. X-ray computerized renal tomography (CRT), dynamic renal scintigraphy (DRS), ultrasonic renal scanning (URS) were used in the study, furthermore, the activities of enzymes (beta-glucuronidase, alanine aminopeptidase, arylsulfatase A), beta 2-microglobulin (beta 2-MG) concentration were determined in the serum and urine. It has been found that combined use of the investigation methods largely increases diagnostic possibilities, significantly expands the data of such invasive procedures as excretory urography, aortography, renal biopsy, and in a number of cases it enables making the diagnosis without applying the invasive procedures. It is advisable to use URS and to determine the enzymatic activity and beta 2-MG concentration in the urine just at the first stage of examining the patients with AH (simultaneously with general clinical methods). When renal pathology is detected or suspected it is necessary to perform DRS. When voluminous process, "mute" kidney, cystic lesions, calculous chronic pyelonephritis are suspected CRT should be employed.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1984
PMID:[Use of dynamic scintigraphy, x-ray computed tomography, ultrasonic scanning of the kidneys and determination of the enzyme activity and beta 2-microglobulin levels of the blood and urine of arterial hypertension patients]. 615 Jul 23

Activity of alanine aminopeptidase (AAP), aryl sulphatase A (ASA) beta-glucoronidase (beta-GA) and the concentration of beta 2-microglobulin in urine was determined in 12 patients with chronic diffuse glomerulonephritis and in 16 patients with essential hypertension. The control group consisted of 6 practically healthy persons. The AAP activity in urine of patients with chronic glomerulonephritis was significantly higher than that in healthy subjects. Renal excretion of lysosomal enzymes (ASA, beta-GA) appeared to be less expressed; no significant differences as regard to their excretion were noted between the above mentioned groups. Concentrations of beta 2-microglobulin in urine of patients with chronic glomerulonephritis 6 times exceeded its concentration in healthy persons and in hypertensive patients, more than 3 times as much. Determination of the enzyme activity and beta 2-microglobulin concentration in urine may serve a test in differential diagnosis, for evaluation of the treatment efficiency of patients with chronic glomerulonephritis accompanied by arterial hypertension and those suffering from essential hypertension.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1982
PMID:[Determination of enzyme activity and beta 2-microglobulin concentration in the urine in chronic diffuse glomerulonephritis and hypertension]. 617 19

Among 1048 patients with essential hypertension undergoing echocardiographic investigation during 1974-1980, 51 patients (4.9%) were found to have asymmetric hypertrophy of the interventricular septum. Eleven of those patients underwent a repeated echocardiography 3-5 years later. Asymmetric disproportionate hypertrophy of the interventricular septum in patients with essential hypertension was found to be one of the variants of concentric hypertrophy formation, and in a few cases--a sign of the development of idiopathic hypertrophic subaortal stenosis in arterial hypertension.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1982
PMID:[Long-term observations of hypertension patients with asymmetrical hypertrophy of the interventricular septum]. 621 69

Captopril was used in 21 patients with various forms of stable and malignant hypertension. In symptomatic hypertension the drug had a good antihypertensive effect. When applied in patients with essential hypertension caused by chronic diffuse glomerulonephritis or chronic pyelonephritis captopril neither increased pathological changes in the urine, nor inhibited renal function.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1983
PMID:[Effect of captopril on the level of arterial pressure and functional state of the kidney in symptomatic (renal) stable and malignant arterial hypertension]. 635 26

In a district polyclinic, psychodiagnostic study of subjects with borderline blood pressure (140/90--159/94 mm Hg) and patients with essential hypertension of the first stage was performed followed by psychotherapy of this group. Psychometric procedures: multisided personality study procedure (modified and restandardized variant of MMPI test and Cattell's 16-factorial personality test) were employed together with clinical examination. Various psychopathological manifestations were observed in 48.1% of the patients examined, which was reflected in the increase in the profile of multisided personality study procedure (MPSP) up to 70. Diastolic blood pressure in these persons rose as MPSP profile increased, and there was no enhancement in systolic blood pressure at that time. Psychotropic drug treatment in combination with psychotherapy of psychopathological symptoms and arterial hypertension proved efficient.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1984
PMID:[Psychodiagnostic examination of patients with the initial stages of arterial hypertension at a district polyclinic]. 650 30

Methods for assessing the social and economic losses due to premature death are considered. The calculation algorithm of such an assessment including economic and demographic aspects has been devised. The calculation methods are illustrated by the results of carrying out the arterial hypertension preventive programs at one of the Moscow large enterprises. Unaccounted discount coefficient and survival expectancy rates are shown to contribute to the increase in the amount of economic losses due to premature death by 30-50%. It is also shown that measures promoting decrease in death rates caused by myocardial infarction and stroke, due to the prevention of arterial hypertension in the organized population groups within 4 years is followed by decrease in labour losses and by increase in economic effect by more that 160 thousand roubles (at the rate per 100 patients with arterial hypertension).
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1984
PMID:[Algorithm for calculating socioeconomic loss in relation to premature mortality]. 650 33


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