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Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The present study is a two year-follow up of 105 eyes (including 27 aphakic eyes), operated on retinal detachment by silicone oil injection after pars plana vitrectomy. This procedure was chosen either as an initial treatment (37 eyes) or after a classical treatment by external indentation had failed (68 eyes). All cases of retinal detachment were of bad prognosis: macular hole, massive periretinal proliferation, isolated or associated with a tear. Cases of vitrectomy with silicone injection for proliferative retinopathy due to diabetes or hemoglobinopathy were excluded. Operations were performed under a surgical microscope with the help of a corneal contact lens (Goldmann, Kl oti or O' Malley ). Functional and anatomical results, as well as complications, were evaluated at least 2 years after treatment. In 24,7% of cases, vision was improved as compared to preoperative visual acuity. Cataract was a constant complication in all phakic eyes, as silicone oil had not been removed within the first 6 months. Intraocular hypertension developed frequently both in phakic and in aphakic eyes (29,5 and 33% of cases, respectively) and responded poorly to medical or surgical treatment. Other complications occurred less frequently. They were corneal edema, conjunctival hyperemia and uveitis. Pain imposed the evisceration of 2 eyes. These complications were the consequence of silicone oil toxicity and/or the mechanical effects of intraocular oil. Besides treatment-associated complications, early (36 during the first 6 months) as well as late (2 between the 12th and 18th months) recurrences of retinal detachment were observed. In contrast to these fair functional results, anatomical results were good in most cases.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Treatment of retinal detachment by vitrectomy and injection of silicone oil. Long-term results and complications in 105 cases]. 647 Apr 12

The investigations were performed on 3 groups of untreated, spontaneously hypertensive Wistar rats of the Okamoto line. All the rats in Group I developed arterial hypertension within 16 weeks of birth and 33 percent of them developed cataracts within 22 weeks. Reserpine application suppressed hypertension and cataract development in all the animals in Group II. After unilateral adrenalectomy and contralateral adrenal enucleation (Group III), hypertension and cataracts developed in both treated and untreated animals; in the former, however, blood pressure was about 10 percent higher and cataracts developed about 6 weeks earlier than in the untreated rats. These findings support the hypothesis that arterial hypertension may be involved in cataract development.
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PMID:[Development of hypertension and cataract in spontaneously hypertensive rats]. 663 77

Records of 849 consecutive diabetic Ethiopians revealed that 171 had type I diabetes, 462 type II nonobese, 210 type II obese, and 4 drug-induced. Undernutrition (BMI less than 18 kg/m2) was present in 12.9% of patients. Forty percent of all patients require insulin; ketoacidosis has occurred in 7.8%. Diabetes was present 10 yr or less in 73%, only 11% have been diabetic more than 15 yr, and none more than 32 yr. During 7 yr, 66 (7.8%) are known to have died. Renal failure caused 30.3% of known deaths, and ketoacidosis 3%. About 4% of those diabetic 6-10 yr have a clinically significant complication. The incidence of "diabetic triopathy" rose rapidly after 10 yr. Of those diabetic 16-20 yr, 27.7% had nephropathy, 27.7% neuropathy, and 33.3% retinopathy. Hypertension was seen in 12.1% of patients without nephropathy. Cataracts were seen in 1.4% of new diabetic patients, rising to 40.7% in those diabetic more than 20 yr. Peripheral vascular disease was uncommon and myocardial infarctions occurred in eight patients. Thus, "diabetic triopathy," hypertension, and cataracts are frequent in and after the second decade of diabetes in Ethiopians.
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PMID:The clinical pattern of diabetes mellitus in Ethiopians. 670 67

In 36 subjects in chronic hemodialysis treatment and in 36 patients with a renal transplant, well functioning for more than one year, the ocular complications related to the specific form of treatment were evaluated and compared. In the group of the dialyzed subjects ocular pathology was composed by: lens opacities in 9 cases, corneal calcifications in 7 cases, hypertensive fundus in 8 cases. In no patient these lesions produced measurable visus reductions. In the transplant group ocular pathology was composed by: lens opacities in 28 patients, hypertensive fundus in 7 and intraocular hypertension in one. One case of herpes cheratytis and one case of endophtalmytis have also been observed. In 9 patients these lesions produced a remarkable visus reduction. In conclusion renal transplantation shows a greater incidence of ocular complications if compared to hemodialysis. This situation has not important consequences on the rehabilitation of the transplanted subject for the possibility of surgical correction of the cataract.
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PMID:[Ocular complications in patients undergoing long-term hemodialysis and renal transplants from cadavers]. 700 28

In order to define the pathology of cystoid macular edema (CME), 35 human cases with histopathologic features of CME were reviewed. The macular cysts appeared in different layers of the retina in eyes after cataract extraction, retinal vein occlusion, trauma, diabetes mellitus, and accelerated hypertension. The pathologic process varied from transudation, exudation to liquefaction necrosis. The experimental models of lens extraction and talc retinopathy in rhesus monkeys were examined. Disruption of the blood-retinal barrier at the retinal vasculature and retinal pigment epithelium were noted after lens extraction. Cystoid degeneration of the macula was seen in monkeys with talc retinopathy. The possibility that disruption of the blood-retinal barrier and microinfarction play important roles in the formation of the macular cysts is proposed.
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PMID:Pathology of cystoid macular edema. 713 37

By means of radioimmunoassay, the content of endogenous cortisol in the aqueous humour and plasma of 35 patients suffering from various types of glaucomas and 35 cataract patients was determined, and the ratio of the plasma to the aqueous humour cortisol levels was calculated. The highest cortisol level in both plasma and aqueous humour was found to occur in patients with open-angle glaucoma suffering at the same time from systemic hypertension. The lowest plasma to aqueous humour cortisol ratio was found in patients with secondary glaucoma treated with steroids. In woman suffering from open-angle glaucoma, the rising cortisol level in plasma with age contrasted to the decreasing cortisol level in aqueous humour. The authors suggest that there is an active interference with homeostatic mechanisms responsible for ensuring the stability of the eye inner milieu and a certain protection of the trabecular meshwork of the angle of the anterior eye chamber against noxious effects of the endogenous cortisol.
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PMID:Aqueous humour and plasma cortisol levels in glaucoma and cataract patients. 731 92

A two year study of one hundred and forty five cataract extractions showed a 38% incidence of post operative macular oedema. The leak had resolved in most cases by six months and the only factor of significance in the production of the oedema was preoperative hypertension. The likelihood of obtaining 6/6 vision postoperatively was much lessened in the presence of macular oedema.
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PMID:The Prince of Wales Hospital prospective aphakic macular oedema study. 742 74

In the ophthalmological field, it is not always easy to adopt a primary prevention. Much more useful would be a secondary prevention program towards the affections at birth or those later developed that, if diagnosed and treated early, grant a normal visual development. Differentiated prevention can be carried out, according to various ages: at the tender age congenital glaucoma and cataract, strabism, ametropia, anisometropia (possible cause of amblyopia) have to be considered; in the adult-senile age must be prevented damages due to hypertension, diabetes, thrombosis, as well as cataract, glaucoma, uveitis, kerato-conjunctivitis and retinal detachment.
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PMID:Epidemiological aspects, development and management of prevention in ophthalmology in relation to different ages. 747 19

The occurrence of early hypotony after trabeculectomy was analysed retrospectively in 60 glaucoma patients. Fifty-two per cent of the eyes had an intraocular pressure < or = 10 mmHg on the first postoperative day. In about one-third of the eyes, the intraocular pressure was < or = 5 mmHg at the first postoperative visit and in more than 70% of these eyes the hypotony was almost unchanged one week after operation. The hypotony one week after operation was not correlated to the age of the patients and the intraocular pressure at operation, nor to the glaucoma type, and showed no significant statistical dependence on the depth of anterior chamber and hyphema. The final untreated intraocular pressure and progression of the postoperative cataract were studied in four groups of patients, formed on the basis of the intraocular pressure level one week after operation: patients with marked hypotony, slight hypotony, normal pressure or with hypertension. The final untreated intraocular pressure in the eyes with early marked hypotony was not significantly different from the final untreated intraocular pressures in the slightly hypotonic and normotonic eyes. However, the untreated intraocular pressures in these three eye groups were significantly different from the untreated intraocular pressure in the eye group with hypertension. Fifty-two per cent of the eyes suffered from cataract progression during a mean follow-up period of 24 months. Postoperative cataract progression in the markedly hypotonic eyes was not significantly different from the cataract progression in the other groups of eyes.
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PMID:Early hypotony after trabeculectomy. 749 40

Clinical renal abnormalities, including haematuria, proteinuria, abnormal urinary sediment, decreased renal functions and hypertension are relatively common in children with juvenile rheumatoid arthritis (JRA). These findings may be due to renal amyloidosis or administration of drugs that are potentially nephrotoxic. The case of an 11 years old boy diagnosed as JRA at 4.5 months of age and treated with steroids for 10 years is presented. In his history he had hypertension for 5 years and cataract for one year. Renal biopsy was done to evaluate the aetiology for proteinuria, which was overlooked before his admission to our Department. Secondary renal amyloidosis due to JRA was found at biopsy. The importance of investigation for amyloidosis during the long-term follow-up of JRA is reemphasized.
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PMID:Juvenile rheumatoid arthritis and renal amyloidosis (case report). 759 86


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