Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The pattern of heart disease in 404 patients seen prospectively from the guinea savanna region of Africa is presented. Over 90% presented with cardiac failure. Hypertension, Peripartal Cardiac Failure (PPCF), Congestive Cardiomyopathy and Rheumatic Heart Disease are major problems. The highest incidence of PPCF in the world probably occurs in this area but the prognosis is good. The reasons for this and the possible interrelationship of hypertension with cardiomyopathy and PPCF are discussed. In contrast to the tropical rainforests, no case of endomyocardial fibrosis was seen. During the period of study, vascular thrombosis is uncommon and coronary heart disease is non-existent in Zaria.
 ...
PMID:Pattern of heart disease in adults of the Nigerian Savanna: a prospective clinical study. 9 46

The case files of 4,456 medical admissions in 1975--1976 at Ahmadu Bello University Teaching Hospital, Kaduna, Nigeria, included 354 cardiovascular patients. The most common causes were hypertension (45.5%), cardiomyopathy (20.6%) and chronic rheumatic heart disease (14.4%). The mean age of hypertensive and cardiovascular patients was lower than in Europe. The majority of hypertensive patients suffer from essential hypertension. Congestive cardiac failure is the commonest complication of hypertension and cardiomyopathy. Rheumatic valvular disease with mitral incompetence is frequent and sometimes severe in young people. Other cardiovascular diseases included pericardial disease, bacterial endocarditis, cor pulmonale, anaemic heart failure, congenital and syphilitic heart disease. Coronary heart disease was only encountered in non-Africans. Cardiovascular mortality in hospital was high (20%).
 ...
PMID:Cardiovascular disease in Northern Nigeria. 31 94

In Switzerland the age-standardised death rate for 'all diseases of the circulatory system' decreased by 22% in males and by 43% in females between 1951 and 1976, which represented a third and nearly a half respectively of the decrease in all deaths. Mortality was reduced by 13% in males and by 40% in females for non-rheumatic heart disease and hypertension, and by 36% and 47% respectively for cerebrovascular disease. These reductions were on the whole greater than those observed in the 13 other developed countries studied. From 1951 to 1976 consumption of animal fats per caput increased by 20% in Switzerland, in spite of a 46% reduction in milk intake. Throughout the same period, smoking increased among women while it remained steady or possibly declined in men. During the last decade a threefold rise in the sales of antihypertensive drugs was observed. Oral contraceptives seem to have been widely used by Swiss women since the 1960s. There were also increases in the proportion of women in professional occupations, and in urbanisation. The advent of the economic recession was associated with a sudden rise in mortality from non-rheumatic heart disease and hypertension in 1974-76.
 ...
PMID:Surprising decline of cardiovascular mortality in Switzerland: 1951-1976. 49 89

The aim of this study was to evaluate the usefulness of M-mode echocardiography as a non-invasive diagnostic tool when facilities for cardiac catheterization were not available. We used this technique to study 275 patients whose clinical diagnosis included hypertension, rheumatic heart disease, cardiomyopathy, peripartum cardiac failure, pericardial disease and some forms of congenital heart disease. Characteristic echocardiographic patterns made specific cardiac diagnoses possible and allowed a distinction to be made between clinically similar conditions. It is concluded that echocardiography is very useful in the African setting because it is safe and repeatable.
 ...
PMID:M-mode echocardiography in the diagnosis of heart diseases in Africans. 55 66

All autopsies on Black patients who died of heart disease at Baragwanath Hospital were examined for the years 1959, 1960 and 1976. The commonest form of heart disease encountered in South African Blacks is undoubtedly hypertensive heart disease and by far the majority of these cases are of essential hypertension. There appears to have been a slight rise in the incidence of hypertension. Rheumatic heart disease is extremely common, and affects young people, who often have advanced valvular lesions by puberty. The incidence of idiopathic cardiomyopathy does not seem to have altered materially, although there has perhaps been a slight drop, which may be accounted for by the tendency of clinicians to place cases of congestive cardiac failure with mild hypertension in the hypertensive group rather than in the idiopathic cardiomyopathy group. There was a significant alteration in the incidence of myocardial infarction; in 1959 and 1960 these cases comprised less than 1% of all cardiac deaths but in 1976 they comprised nearly 12%. There has also been a dramatic fall in the incidence of cardiovascular syphilis.
 ...
PMID:The changing pattern of heart disease in South African Blacks. 60 91

Diseases of urban and rural Blacks in South Africa are reviewed. In rural Blacks the major problems are infection and malnutrition. Other important disorders include cancer of the oesophagus, liver and cervix, and rheumatic heart disease and cardiomyopathy. The diseases in urban Blacks are those of a population in transition. Characterised by all gradations of socioeconomic development, from the relatively primitive to the completely westernised, these people exhibit a correspondingly wide and varied range of disease embracing the afflictions of rural dwellers and the new diseases of the city. Whereas the prevalence of some of the former, such as infection and malnutrition, is declining, they still constitute a considerable problem in urban Blacks. More important is the increasingly serious impact of the new disorders, which may be divided into two groups: (a) a large range and variety of alcohol-related disorders with serious effects at the social, economic, psychological and physical levels; and (b) most, if not all, of the diseases encountered in western populations. Some of these, such as obesity and hypertension, have not only attained epidemic proportions among urban Blacks, but their prevalence may actually have exceeded that among Whites. Other conditions, such as coronary heart disease, gout, gallstones and colonic cancer, which emerged later, are relatively uncommon or rare. A plea is made for much greater epidemiological research. This is necessary in order to obtain reliable knowledge of the prevalence of disease, to determine the best ways of applying present knowledge with existing and future resources, and to obtain knowledge regarding both old and new diseases of which the pathogenesis is still obscure.
 ...
PMID:Diseases in urban and rural Black populations. 85 Aug 43

The high incidence, great import, and long duration of cardiovascular diseases are reflected in high demands placed on the health services. Experience shows that utilization of the results of research in general practice is lagging behind. The application of any improvement in the diagnosis, therapy, and prevention in health care waits several years for its accomplishment. In order to improve this situation, the Ministry of Health of the CSR constituted, in line with WHO recommendations, a Department for Cardiovascular Diseases Control. The Department has worked out a programme of prevention and control of the major cardiovascular diseases, in particular, ischaemic heart disease, systemic hypertension and its complications, rheumatic heart disease, congenital cardiac and vascular defects, and cor pulmonale. New diagnostic, therapeutic, and preventive procedures are first tried out in so-called model areas and are only after this introduced into the national health care of people suffering from or endangered by cardiovascular diseases. In parallel, organizational measures necessary for comprehensive care are implemented. The authors report on the experience gained so far with the realization of the programme of care of people suffering from IHD and acute myocardial infarction. They emphasize the importance of continual schooling of medical personnel and of health education of the entire population. They describe the implementation on a national scale of postgraduate cardiological courses intended especially for first-line doctors.
 ...
PMID:Present state of cardiovascular community control programme in the Czech Socialist Republic. 94 76

The essential implication of the notion of risk factor is that preventive action should be undertaken if certain factors, predisposing to cardiovascular diseases are present in an individual or in a group. Risk factors are thus categorized from the pragmatic point of view, according to the relative ease and practicability of prophylactic intervention -- and their justification. A brief review of the risk factors of the major cardiovascular diseases (coronary heart disease, hypertension, chronic pulmonary heart disease, stroke, rheumatic heart disease and congenital malformations) shows that the risk factor concept is the basis of preventive cardiology.
 ...
PMID:[Use of the risk factor concept in cardiovascular diseases (author's transl)]. 100 56

A survey was carried out amongst 7062 people of different age groups in Dacca city and in a village. It was found that 207 (2.92%) persons had some sort of heart disease. Hypertension was present in 83 (1.10%) persons. Rheumatic heart disease, ischaemic heart disease and cardiac arrhythmia were detected in 53 (0.75%), 24 (0.33%) and 16 (0.22%) persons respectively. Congenital heart disease was found in 13 (0.18%) individuals, and 18 (0.25%) persons were suffering from cardiomypathy or corpulmonale. Rheumatic heart disease was common in poor people of younger age. More ischaemic heart disease was found in well-to-do people but poor people were not immune from this.
 ...
PMID:Congenital and acquired heart diseases: (A survey of 7062 persons). 103 68

An analysis of the work content of the physician-specialist at Apia General Hospital, Western Samoa, over a 12-month period in 1973-74 is described. Respiratory infections, rheumatic heart disease, hypertension, diabetes, peptic ulcer, and various forms of liver disease were encountered most commonly.
 ...
PMID:The physician-specialist in Western Samoa. 105 46


1 2 3 4 5 6 7 8 9 10 Next >>