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The authors report 6 cases of severe and silent aortic insufficiency having simulated in all aspects the picture of a dilated cardiomyopathy at the stage of cardiac insufficiency with primary manifestations. They insist on signs leading to the diagnosis of this clinical entity: past history of rheumatism, signs of electrical left ventricular hypertrophy in the absence of arterial hypertension, aortic calcifications and mostly presence of a discrete mitral diastolic fluttering during echocardiographic examination. Supra-sigmoid aortic angiography confirms the diagnosis of severe aortic regurgitation. In order to explain the non-perception of the murmur, they invoke the alteration of the transmission secondary to an air cushion (3 cases the association of another valvulopathy with murmur (1 case) and mainly the decrease of the leakage by increase of the left ventricular telediastolic pressure and the decrease of the diastolic aortic pressure, with diminution of the turbulences. The advantage of knowing this entity rests on the possibility of valve replacement, even at the stage of myocardial failure, since the satisfactory long-term post-operative evolution in 4 patients stands in contrast with the dangerous nature of a spontaneous evolution.
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PMID:[Silent aortic insufficiency mimicking dilated cardiomyopathy]. 359 58

The authors report three patients with systemic lupus erythematosus (S.L.E.) who developed primary retinal vasculitis. All patients showed evidence of four American Rheumatism Association diagnostic criteria for S.L.E. The first case consisted of a woman with retinal central vein occlusion. Auto-immunization against retinal S antigen was present. She improved under heparin therapy. In the second case, a young girl had chronic optic disk vasculitis for seven years. In the third case, retinal arterial occlusive disease was present with optic nerve involvement. The differential diagnosis with multiple sclerosis is discussed. S.L.E. is considered as autoimmune disease where circulating immune complexes play a major role in the pathogenesis. The ocular complications are probably a manifestation of the widespread systemic disease in patients without arterial hypertension. The authors summarize the ocular findings in S.L.E.: venous obstruction, constriction of retinal arteries, capillary vasculitis and disc neuritis. In some cases, there may be the first manifestations of the disease.
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PMID:[Retinal vasculitis in systemic lupus erythematosus]. 674 12

Clinical and pathogenetic peculiarities of cerebral strokes in patients suffering from rheumatism were studied. Comparative data (little described in literature) on certain peculiarities of the manifestations of acute cerebral circulation disorders in patients of different age, as well as in patients with rheumatism-accompanying cerebral atherosclerosis and arterial hypertension are presented. A considerable incidence of hemorrhagic strokes and their clinical heterogeneity are noted. Problems of the pathogenesis of the cerebrovascular disorders are discussed.
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PMID:[Features of the clinical picture and pathogenesis of strokes complicating rheumatism among patients in the older age groups]. 706 11

The study investigated the Taiwanese elderly in two different ethnic groups (Paiwan and Min-Nan) regarding their multifunctional status. The purpose was to make known and compare the subjective and objective health status of these two groups. The results for the objective measurements indicated that an elderly Paiwanese had 2.74 kinds of diseases on average. The most prevalent diseases among the Paiwan elderly were arthritis (rheumatism), circulation troubles in arms or legs, high blood pressure, stomach or intestinal disorders or gall bladder problems, cataract, heart trouble, emphysema (chronic bronchitis), skin disorder (leg ulcers or severe burns), asthma, and digestive system ulcers. Of all disease, five (arthritis, circulation trouble, emphysema, skin disorder, and tuberculosis) were statistically more prevalent among the Paiwan elderly than among the Min-Nan elderly. In terms of health scoring, the two groups were comparable except in the following two aspects: (1) more Paiwan elderly were unable to take medicine by themselves, and (2) the Paiwan elderly had lower cognitive ability ratings. In the subjective arena, the Paiwan elderly had a lower score in self-rating health status. Condensed, the health status of the Paiwan was worse than that of the Min-Nan elderly both in objective and subjective measurements.
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PMID:[A comparison on health status between Paiwan and Min-Nan elderly]. 808 76

In pre-colonial times, health in some Pacific countries was good compared with that of Europe. Illnesses such as scrofula, rheumatism, and filariasis often received herbal treatment. More recently, however, traditional diet throughout the region have been replaced by canned fish, biscuit, white flour products, and sugar-laden food. New illnesses and diseases have emerged in Pacific countries since European intrusion. Though malaria is still the primary cause of death in Vanuatu, diabetes, hypertension, obesity, and coronary heart disease are prime health concerns in most Pacific countries. In Kiribati, health educators use materials in discussion groups and schoolteachers use special materials on AIDS in their teaching, Calendars are produced in cooperation with national nutrition and family planning (FP) groups and agencies that highlight health topics such as AIDS and vitamin-A deficiency. Material produced by the Vanuatu health education unit features nutrition, the environment, FP, and AIDS and other sexually transmitted diseases. The government's Women's Affairs Department the International Labor Organization and other agencies are involved in FP and family life education. In Fiji and the Solomon Islands, nutrition has been highlighted in health education campaigns. In both countries surveys indicated alarming levels of diet-related disease. Another important nutrition project in the Solomon Islands is the village education program. At a training center, trainers conduct 15 practical courses for mobile workers, community workers, and village resource persons. Under this program, 60 village-level workshops are held each year focusing on nutrition, cooking, and gardening. Nutrition is now a major focus of health in the Pacific. The health, nutrition, education, fisheries, and agricultural sectors work with other agencies for success through community participation and through an integrated approach.
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PMID:Popular participation in community health programmes. 818 58

The study covered mortality among a cohort of geologists working in North-Western Russia. The cohort included 3911 geologists, geophysicists and drillers, whose life was followed during 1977-1992. The standardized relative mortality risk with all death causes equalled 0.58 in general. Risk of mortality with hypertension in the male geologists was 21.7 times higher and for the female ones-25.4 times higher than for general population. Definite dependence between the stronger effects and the longer length of service was seen. The highest standardized relative mortality risk appeared among the drillers. Occupational risk factors for geologists reliably increase risk of mortality with active rheumatism, diseases involving arteries, veins and lymphatic vessels. The male geophysicists tend to have higher incidence of prostatic cancer, and female ones-higher incidence of uterine carcinoma.
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PMID:[Mortality of geologists in relation to occupational activities]. 870 38

The aim of the investigation was microalbuminuria evaluation as an early symptom of renal involvement in systemic lupus erythematosus (SLE). Thirty patients aged 18 to 66 years (mean: 39,4 years) with mean duration of SLE of 6,3 years (range: 0,5 to 22 years) were examined. All of them fulfilled the preliminary criteria of the American Rheumatism Association for the classification of SLE. During the study none of patients had clinical or laboratory symptoms of nephropathy, hypertension, diabetes mellitus and heart failure. Microalbuminuria was measured by immunoturbidimetric method and the urine microalbumin concentration was expressed as the ratio microalbumin-creatinine concentration in 24 hour urine [equation: see text] Ratio I was 3,36 (+/- 2,76) in patients suffering from SLE comparing to I = 1,35 (+/- 0.89) in normal controls (p < 0.001). There was no correlation between increasing microalbuminuria and patients age and duration of disease. There was also no correlation between microalbuminuria and erythrocyte sedimentation rate or immunological activity parameters (i.e. antinuclear antibodies, anti dsDNA antibodies, levels of C3 and C4 components of complement).
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PMID:[Microalbuminuria in patients with systemic lupus erythematosus]. 912

The purpose of the National Exposure Registry is to assess the long-term health consequences to a general population from long-term, low-level exposures to specific substances in the environment. This study investigates the health outcomes of 1,143 persons (1,127 living, 16 deceased) living in south central Texas who had documented environmental exposure to benzene (up to 66ppb) in tap water. As with all subregistries, face-to-face interviews were used to collect self-reported information for 25 general health status questions. Using computer-assisted telephone interviewing, the same health questions were asked 1 year (Followup 1, F1) and 2 years later (Followup 2, F2). The health outcome rates for Baseline and Followup 1 and 2 data collections for the Benzene Subregistry were compared with national norms, that is, the National Health Interview Survey (NHIS) rates. For at least one of the three reporting periods, specific age and sex groups of the Benzene Subregistry population reported more adverse health outcomes when compared with the NHIS population, including anemia and other blood disorders, ulcers, gall bladder trouble, and stomach or intestinal problems, stroke, urinary tract disorders, skin rashes, diabetes, kidney disease, and respiratory allergies. Statistically significant deficits for the Benzene Subregistry population overall were found for asthma, emphysema, or chronic bronchitis; arthritis, rheumatism, or other joint disorders; hearing impairment; and speech impairment. No statistically significant differences between the two populations were seen for the outcomes hypertension; liver disease; mental retardation; or cancer. These results do not identify a causal relationship between benzene exposure and adverse health effects; however, they do reinforce the need for continued followup of registrants.
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PMID:The National Exposure Registry: analyses of health outcomes from the benzene subregistry. 956 45

Sixty-eight Nigerians were seen, investigated and treated for soft tissue rheumatism. Most of the subjects had capsulitis of the shoulder, commonly associated with Diabetes mellitus and Hypertension. Other diagnostic groups were however seen. The treatment modalities were basically intra articular steroids, analgesics and physiotherapy.
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PMID:Soft tissue rheumatism among Nigerians. 1045 66

791 patients aged 15-44 years with different forms of cerebral stroke that accounted for 9.4% from all the patients hospitalized because of stroke were treated. Ischemic stroke (IS) was diagnosed in 477 patients (60.3%), hemorrhagic stroke (HS) in 293 patients (37.3%), thromboses of the sinuses and veins of the brain in 19 patients (2.4%). IS to HS was 1.6:1; cerebral strokes were observed in men twice as frequently as in women. The main causes of HS (180 men, 115 women) were anomalies of cerebral vessels and arterial hypertension. Intracerebral and subarachnoidal hemorrhage occured with the same frequency. 38% of the patients died. The main causes of IS in 477 patients (285 men, 192 women) were arterial hypertension, rheumatism and atherosclerosis of cerebral and precerebral arteries. Embolic strokes occurred 4,5 times more frequently in women, than in men. 6.7% of the patients died. Among the patients with disorders of venous cerebral circulation (13 women, 6 men) 2 women with thrombosis of upper longitidinal sinus died. According to authors' data pregnancy and delivery are a significant risk factor for development of all forms of cerebral stroke.
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PMID:[Cerebral strokes at young age]. 1066 80


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