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Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Benign intracranial hypertension (pseudotumor cerebri) is a syndrome of intracranial hypertension that classically presents with headaches and visual disturbance. Physical examination discloses papilledema. Diagnosis is confirmed by a normal cranial computed tomographic scan or magnetic resonance image and the presence of a markedly increased opening pressure on lumbar puncture. Treatment is directed to underlying causes, hypertension, and withdrawal of offending medications. Repeated lumbar puncture, diuretic therapy, and surgery are occasionally used. Careful follow-up and visual testing are imperative.
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PMID:Benign intracranial hypertension. 240 1

Idiopathic intracranial hypertension is a diagnosis most frequently made in young, overweight women. The chief hazard to the patient is permanent visual loss due to chronic papilledema. After the diagnosis has been clearly established using lumbar puncture and imaging techniques, the neurologist is involved in helping to lower the intracranial pressure, control the headaches, and encourage weight loss. Careful vision monitoring is essential and should be done in collaboration with an ophthalmologist. Visual fields, fundus photographs, intraocular pressure measurement, and visual acuity should be performed at each follow-up visit. The use of visual evoked response and repeated measurement of intracranial pressure by lumbar puncture do not provide data that help to guide therapeutic decisions. Indications for surgery are loss of visual field or decline in visual acuity in the fact of medical therapy, persistent headache, or the inability to perform visual-function studies. Optic nerve sheath fenestration and lumbar peritoneal shunt both appear to be effective surgical means to reduce the pressure on the optic disc. A neurologist and an ophthalmologist working together provide the evidence on which to base rational decisions in the care of the patient with idiopathic intracranial hypertension.
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PMID:The rational management of idiopathic intracranial hypertension. 267 6

The concepts of serous meningitis, pseudotumour cerebri, hypertensive meningeal state and otitic hydrocephalus have not been considered historically as synonyms nor can they be superimposed on what is currently known as Benign Intracranial Hypertension (BIH). BIH is a syndrome of intracranial hypertension with no clinical, radiological or analytical evidence for the existence of focal or general neurological lesions or hydrocephalus, and which has a self-limiting "benign" development. At present, the diagnostic criteria usually accepted are: 1. Symptoms and signs of intracranial hypertension. 2. Absence of focal neurological symptoms and signs. 3. Absence of radiologically verified cerebral lesion. 4. C.S.F. of normal composition and high pressure. The requirement of other criteria for the diagnosis of BIH, such as angiography, to eliminate the possibility of thrombosis of venous sinuses, or continuous monitoring of C.S.F. pressure, is controversial.
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PMID:[Historical and current concept of benign intracranial hypertension]. 269 89

Benign intracranial hypertension with papilloedema developed in a 18-year-old woman following Minocycline administration. Tetracycline therapy was prescribed for acne vulgaris. One month after the beginning of the treatment, she presented with headache, nausea and vomiting; there were no visual symptoms. Visual acuity and visual field were normal, fundus examination showed bilateral papilloedema. After Minocycline was discontinued and steroid therapy was administrated, symptoms rapidly resolved and papilloedema disappeared. Minocycline is known to penetrate into the central nervous system more effectively and to have a greater lipoid solubility than the other antibiotics of the same group. However the pathogenesis of benign intracranial hypertension after Minocycline therapy remains unknown.
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PMID:[Papilledema caused by minocycline: apropos of a case]. 297 95

Nineteen patients affected by Pseudotumor Cerebri and treated in the Neurosurgical Department of U.S.L. 10/D of Florence, are considered by Authors. Patients age varied from 4 to 14 years and their selection was made following Boddie, Banna and Bradley criteria published in 1974. Plain X Ray of the Skull was positive in 5 cases while ventriculography (when executed) were always normal. Quite normal were Angiography and CT scan. There were no pathological findings in CSF. The series of patients is considered analyzing somatic features, sex and possible aetiologic noxae. An interesting data is the presence of fever (39 degrees C) from 7 to 20 days before the onset of cranial hypertension. The possibility of blood-brain barrier alteration following infectious disease which causes an interstitial edema is considered and proposed by authors as a starting point for future research.
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PMID:[Pseudotumor cerebri: 19 cases in childhood]. 378 86

A 35 year-old caucasian man suffered from paroxysmal nocturnal haemoglobinuria (PNH) or Marchiafava-Micheli's disease diagnosed in 1976 and complicated by several thrombotic episodes. He developed a benign intracranial hypertension. A digitalized intravenous angiography showed occlusion of both lateral sinuses. Partial improvement followed lombo-peritoneal shunting and steroid therapy. Cerebral venous thrombosis is a well-known complication of PNH but only a few cases have been radiologically and/or pathologically proven. It usually involves the superior longitudinal sinus and/or cortical veins resulting in hemorrhagic infarction of poor outcome. Benign intracranial hypertension due to a venous occlusion is rare. In 3 published cases, as in our own, the neurologic outcome was good. Steroid therapy seems useful. The risks of anticoagulant therapy are discussed.
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PMID:[Benign intracranial hypertension and Marchiafava-Micheli disease]. 382 10

Pseudotumor cerebri, or benign intracranial hypertension, is relatively rare in children. A 12-year-old girl with Hashimoto hyperthyroidism and hypovitaminosis A is described, who fulfilled the diagnostic criteria for pseudotumor cerebri.
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PMID:Pseudotumor cerebri associated with hypovitaminosis A and hyperthyroidism. 383 56

Pseudotumor cerebri or benign intracranial hypertension is a syndrome characterized by increased intracranial pressure without focal signs of neurologic dysfunction. The clinical manifestations of this syndrome are usually headache and/or disturbance of vision. Although tinnitus, hearing loss, and vertigo have been described in association with intracranial hypertension, otologic symptomatology as the presenting manifestation of this syndrome has not been previously reported. In this article we report the otologic symptoms and findings of two pseudotumor cerebri patients, one of whom presented with pulsatile tinnitus. The pathogenesis of the otologic symptoms, diagnostic workup, and management of these patients are discussed.
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PMID:Otologic symptoms and findings of the pseudotumor cerebri syndrome: a preliminary report. 392 38

A 22-year-old patient with hemoglobin SC disease developed benign intracranial hypertension during two successive pregnancies; both resulted in uncomplicated vaginal deliveries of healthy male infants. Benign intracranial hypertension in pregnancy and its management are discussed.
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PMID:Recurrent benign intracranial hypertension associated with hemoglobin SC disease in pregnancy. 394 68

Five patients with serious ocular complications of benign intracranial hypertension are described. Optic nerve sheath fenestration resulted in resolution of papilloedema with, in three instances, improvement in vision. Benign intracranial hypertension may not always be benign for vision and fenestration operations may prevent or reverse visual deterioration by an effect on the optic nerve rather than by reducing intra-cranial pressure.
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PMID:Benign intracranial hypertension: visual loss and optic nerve sheath fenestration. 395 37


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