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Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

One third of 160 operatives working in a permanently noisy industrial environment, within the range of 63-8000 Hz and intensity of sound of about 100 db, were found to suffer from a syndrome of neurocirculatory asthenia and 8.1% from arterial hypertension. Study of the ECG according to the criteria of the Minnesota code showed an increased frequency of upward deflection of ST segment (index 9-2) in 20.6% of the cases, depression of the ST segment with an ascending orientation in 50.62% of the cases and left ventricular hypertrophy (index 3-1 and 3-3) in 20% of the cases. Audiometry revealed loss of hearing at frequencies of 4000 CS in 16.1% of the cases. The results obtained suggest that the detrimental effects are not restricted only to hearing, but also that the alterations detected might evolve towards organic cardiac disorders.
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PMID:Study of cardiovascular and auditory pathophysiological implications in a group of operatives working in noisy industrial surroundings. 40 53

The paper is concerned with the implication of vertebral complaints in connection with cardiac neurosis and the reinforcement mechanism which maintains the symptom pattern. 31 psychiatric patients with cardiac symptoms and 10 patients with solely vertebral symptoms were examined neuro-orthopedically as well as by clinical and psychological tests. The results indicated that patients with distinct organic signs as muscle hypertension, blocked vertebrae and tenderness on pressure appear to be more anxious, tensed and irritated in the paper pencil tests. This leads to the hypothesis that the organic patients are more sensitive to external and internal stimuli, which causes a higher inclination for muscle tension and therefore vertebral alteration. These alterations again are responsible for internal stimuli like pain and discomfort in the cardiac region. So a cycle is established which can be interrupted by different therapeutic steps, especially cognitive behavioral approach.
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PMID:[Somatic disorders in cardiac phobia]. 45 74

1. In thirty six patients with various circulatory diseases, the influence of exercise on myocardial carbohydrate metabolism was observed by use of coronary sinus catheterization. Bicycle ergometry was performed in supine position at a level of fifty watts for fifteen minutes. 2. The myocardial carbohydrate metabolism was not significantly affected by the manipulations with coronary sinus catheterization. 3. At resting state, there was no significant difference among disease groups except that myocardial lactate extraction ratio showed lower values in some cases of the patients with coronary heart disease. 4. During exercise, in cases of neurocirculatory asthenia and hypertension without coronary insufficiency, the myocardial carbohydrate usage was increased with the increase in coronary blood flow and the arterial concentration, maintaining of the carbohydrate extraction ratio. In cases of hypertensive coronary failure, the myocardial carbohydrate usage was maintained chiefly with remarkable increase in the arterial concentration in spite of no significant change of coronary blood flow and the carbohydrate extraction ratio. In normotensive coronary heart disease, the myocardial carbohydrate usage decreased or slightly increased, chiefly due to strong decrease in the extraction ratio and to the lowest increase in coronary blood flow. In many cases the carbohydrate release out of the heart muscle was observed. For the most of the cases of the other heart diseases, the latent disturbance of myocardial carbohydrate metabolism was revealed by exercise in spite of the good response of coronary circulation. 5. The myocardial uptake, extraction ratio and usage of lactate were significantly lower in the ischemic ECG positive group than in the negative group, in spite of significantly higher increase in the arterial concentration in the positive group. The myocardial metabolism of pyruvate during exercise was similar to that of lactate, but the myocardial metabolism of glucose was not clearly correlated with ECG changes.
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PMID:[Study on myocardial carbohydrate and energy metabolism during exercise in patients with circulatory diseases (author's transl)]. 115 95

Neurocirculatory asthenia (NCA) is a fairly common functional disorder often encountered among military recruits. Symptoms in NCA tend to appear in waves, and are believed to disappear completely with the passage of time. Elevated arterial pressure is known to occur as part of the various haemodynamic manifestations of NCA. However, the exact prevalence of hypertension, as well as its long-term prognosis, is still unknown. The present case-control study was designed to address these two issues. The target population consisted of 370 patients with NCA representing two separate cohorts: patients diagnosed in 1979, 10 years prior to this study, and patients diagnosed in 1983-84, 5 years prior to the study. An overall 20% prevalence rate of mild hypertension at diagnosis was calculated for the entire study population. In total, 100 patients representing equal numbers of hypertensive and matched normotensive subjects from each cohort were re-evaluated. At follow-up, hypertension was present in 27% (1979 cohort) and 30% (1983-84 cohort) of patients originally considered to be hypertensive. Hypertension was either non-existent (1979 cohort) or limited to a single case (1983-84 cohort) among originally normotensive individuals. In parallel, resting heart rate was higher in the hypertensive subjects of the 1979 cohort both at presentation (85.5 +/- 3.2 vs. 73.7 +/- 2.4 beats min-1; P less than 0.005) and at follow-up (79.6 +/- 3.2 vs. 70.0 +/- 2.5 beats min-1; P less than 0.01). These results indicate that hypertension complicates the diagnosis of NCA in 20% of patients and that, contrary to common belief, it cannot be regarded as another transient manifestation of this condition. Thus hypertension in this context is, as in the younger members of the population in general, a major risk factor for lifelong hypertension, rather than an inconsequential phenomenon.
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PMID:Neurocirculatory asthenia revisited: elevated arterial pressure at presentation is a marker for subsequent hypertension. 160 87

Adaptation to periodic hypoxia (decompression 490 mm Hg) in a multiplace medical pressure chamber of patients with hypertension, cardial neurocirculatory asthenia, coronary heart disease produced a persistent hypotensive effect with improvement of central and peripheral hemodynamics, oxygen homeostasis, electrolyte balance of blood. In patients with neurocirculatory asthenia associated with ventricular and supraventricular extrasystole positive hemodynamic changes accompanied a persistent antiarrhythmic effect. In addition to the latter, CHD patients experienced improvement in myocardial contractility. Clinical effect of baroadaptation to hypoxia manifesting in symptom relief permitted the physicians to diminish the intensity of chemotherapy and to abolish it in patients with neurocirculatory asthenia.
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PMID:[Experience in treating patients with cardiovascular diseases by means of adaptation to periodic barochamber hypoxia]. 916 53

The authors present the results of clinical, physiological and psychological examination of 31 patients with neurocirculatory asthenia with arterial hypertension syndrome. There was an increase in the levels of state and trait anxiety correlated with a number of physiological traits that confirmed a leading role of psycho-emotional sphere in the formation of hypertensive reactions. An evaluation of the efficacy of the drug Adaptol used in daily dosage 1500 mg during 8 weeks in the treatment of these patients revealed its high efficacy (the improvement was seen in 74% of cases) confirmed by the data of clinical and psychological studies.
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PMID:[Neurocirculatory asthenia: psychoautonomic features and treatment possibilities]. 2338 93