Gene/Protein
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Drug
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Pivot Concepts:
Gene/Protein
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Target Concepts:
Gene/Protein
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Query: UMLS:C0020538 (
hypertension
)
170,190
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Adrenal cortical tumour
-induced malignant hypertension is rare, except for some documented aldosterone-producing adenomas.
Hypertension
is a common feature of Cushing's syndrome, whereas malignant hypertension is rarely seen. This case in Taiwan is only the second reported case with malignant hypertension secondary to a cortisol-secreting adrenal tumour. The immunohistochemical study of the excised tumour showed strong positive staining of interleukin (IL)-6. IL-6 can trigger inflammatory vascular damage, which is typical in the malignant phase of
hypertension
. We hypothesise that IL-6 may have played an important role in this case.
...
PMID:Malignant hypertension secondary to cortisol-secreting adrenal tumour. 1593 32
