Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020505 (hyperphagia)
 6,116 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
insulin 961
leptin 610
Sep 370
neuropeptide Y 245
ghrelin 155
gut 130
Leptin 120
beta-endorphin 116
Mol 112
leptin receptor 110
growth hormone 97
glucagon 96
proopiomelanocortin 95
cholecystokinin 81
agouti 81
ACTH 76
ART 72
orexin 71
NPY 70
Neuropeptide Y 65
She 64
prolactin 52
albumin 50
melanocortin-4 receptor 47
oxytocin 43
melanin-concentrating hormone 40
GABA 40
opioid receptor 39
Ghrelin 39
uncoupling protein 1 38
uncoupling protein 37
epididymal 37
peptide YY 35
serum albumin 33
CCK 33
CB1 33
galanin 33
5-hydroxytryptamine 33
MRI 32
5-HT1A 32
somatostatin 31
cytokine 30
brain-derived neurotrophic factor 29
melanocortin 4 receptor 29
cocaine- and amphetamine-regulated transcript 28
adiponectin 27
melanocortin receptor 27
ATP 26
STAT3 25
AMP-activated protein kinase 25
olfactory 25
GDP 25
MC3 24
lipoprotein lipase 24
insulin receptor 23
Gen 23
MC4R 23
vasopressin 21
Orexin 21
mTOR 20
bombesin 19
collagen 19
cannabinoid receptor 19
HDL 18
cage 18
amylase 18
hemoglobin 18
STZ 17
corticotropin-releasing factor 17
ghrelin receptor 17
dynorphin 17
c-fos 16
UCP2 16
GLP-1 16
transferrin 16
tumor necrosis factor 16
thyroid hormone 16
Y5 receptor 16
fatty acid synthase 15
GHRP 15
IL-6 15
5-HT2C 14
Brain-derived neurotrophic factor 14
reserved 14
5-HT2A 14
Prolactin 14
MSH 14
5-HT1B 14
CRH 14
peroxisome proliferator-activated receptor 14
rat) 14
TPN 13
adrenocorticotropic hormone 13
glucose transporter 13
pancreatic polypeptide 13
glucocorticoid receptor 13
signal transducer and activator of transcription 3 13
OFQ 12
UCP3 12
short form 12
calcitonin 12
axonal 12
TNF 12
GLP-1 receptor 12
alkaline phosphatase 12
gastrin 12
tyrosine hydroxylase 12
neurotensin 12
SNRPN 12
IRS-1 12
ARC 12
superoxide dismutase 11
interleukin-6 11
AMPK 11
prealbumin 11
lipopolysaccharide 11
CSF 11
endoplasmic reticulum 11
insulin-like growth factor 11
lipase 11
glucokinase 11
aspartate aminotransferase 11
suppressor of cytokine signaling 3 11
MAGEL2 10
phosphoenolpyruvate carboxykinase 10
PWS 10
IGF-1 10
ANOVA 10
GLUT4 10
ferredoxin 9
nitric oxide synthase 9
thyrotropin-releasing hormone 9
CCK-A 9
CO2 9
dopamine D2 receptor 9
casein 9
B12 9
AKT 9
acetyl-CoA carboxylase 9
Growth hormone 9
C-reactive protein 9
adipokine 9
chronic renal failure 9
amylin 9
phosphatase 9
Pol 9
STAT 9
catalase 8
PPAR 8
JAMA 8
IgA 8
Y2 receptor 8
5-HT receptor 8
substance P 8
microsomal 8
Proopiomelanocortin 8
threonine 8
retinol-binding protein 8
estrogen receptor 8
alanine aminotransferase 8
more...
Disease
hyperphagia 6116
obesity 2195
diabetes 585
hyperglycemia 225
hyperinsulinemia 210
depression 197
binge eating 191
cancer 163
malnutrition 144
type 2 diabetes 142
sepsis 136
eating disorder 135
bulimia nervosa 130
metabolic syndrome 123
sepsis 120
addiction 112
glucose intolerance 110
hypertension 108
cold 99
tumor 93
hypogonadism 87
anorexia nervosa 84
morbid obesity 73
disinhibition 72
hypoglycemia 70
fatty liver 63
hyperlipidemia 62
genetic disorder 57
Syndrome 54
Evans 49
cardiovascular disease 47
dyslipidemia 44
mental retardation 42
developmental delay 39
carcinoma 38
mental retardation 38
malabsorption 38
Kleine-Levin syndrome 36
failure to thrive 36
dementia 35
hypothyroidism 35
hypersexuality 35
mental illness 33
major depressive disorder 33
SAD 33
aggression 32
cognitive impairment 31
overnutrition 31
substance abuse 30
anemia 29
renal failure 29
hypercholesterolemia 29
type 1 diabetes 28
alcoholism 28
growth hormone deficiency 26
Alzheimer's disease 26
pancreatitis 26
short bowel syndrome 25
autism 25
dehydration 24
hyperthyroidism 24
pneumonia 24
SEM 23
epilepsy 22
peritonitis 22
hypercortisolism 22
schizophrenia 22
chronic disease 21
sleep disorders 21
drug abuse 21
acute renal failure 21
renal disease 21
fungemia 21
atherosclerosis 21
Crohn's disease 21
Brown 21
infectious diseases 20
bacteremia 20
drug addiction 20
bowel obstruction 19
infertility 19
coma 18
substance use disorders 17
psychosis 17
Infection 17
cirrhosis 17
encephalopathy 17
candidiasis 17
substance use 16
dysphagia 16
hyperprolactinemia 16
stroke 16
respiratory failure 16
fungal infection 15
psychological stress 15
chronic renal failure 15
craniopharyngioma 15
diabetes insipidus 15
acute pancreatitis 14
abdominal obesity 14
chylothorax 14
tumor growth 14
endophthalmitis 14
sleep apnea 14
confusion 14
NAME 13
Bardet-Biedl syndrome 13
bipolar disorder 13
heart disease 13
Angelman syndrome 13
leukemia 13
diabetic ketoacidosis 13
pneumothorax 13
ileus 13
liver disease 13
endocarditis 12
compulsion 12
myocardial infarction 12
anxiety disorders 12
cystic fibrosis 12
cholestasis 12
gallstones 12
Cushing's syndrome 12
neuropathy 12
adrenal insufficiency 12
ketosis 12
wasting 11
ADHD 11
ulcerative colitis 11
cardiomyopathy 11
hepatitis 11
alcohol abuse 11
lymphoma 11
pica 11
Hypothalamic obesity 10
Wernicke's encephalopathy 10
congestive heart failure 10
gastric cancer 10
ischemia 10
neutropenia 10
social stress 10
insulinoma 10
hydrocephalus 10
osteomyelitis 10
hypogonadotropic hypogonadism 10
proteinuria 10
gastroesophageal reflux disease 10
moderate obesity 10
metabolic disorder 10
coronary artery disease 10
osteoporosis 10
ARC 10
arthritis 10
hypopituitarism 9
acute lymphoblastic leukemia 9
adenoma 9
emotional distress 9
compulsive overeating 9
affective disorder 9
delusions 9
more...
Symptom
overweight 337
hunger 225
polydipsia 189
anorexia 167
polyuria 132
hypotonia 113
vomiting 92
hypersomnia 83
diarrhea 82
fatigue 82
pain 78
starvation 75
hypothermia 41
seizures 39
abdominal pain 36
sleepiness 36
cachexia 35
lethargy 30
insomnia 27
nausea 23
weakness 23
anesthesia 21
apathy 20
ataxia 16
analgesia 16
dyspnea 15
hypoproteinemia 13
respiratory distress 13
discomfort 12
emaciation 12
aphagia 12
agitation 11
discomfort 11
chest pain 10
distraction 10
constipation 9
Ill 8
hepatomegaly 8
headache 8
acute stress 7
stigma 7
memory loss 6
cough 6
adipsia 6
hopelessness 6
ketonuria 6
decreased appetite 6
nausea and vomiting 6
regurgitation 6
erythema 5
back pain 5
colic 4
bloating 4
ophthalmoplegia 4
hyperemesis gravidarum 3
leg edema 3
thirsty 3
Depressive symptoms 3
dysarthria 3
shortness of breath 3
heartburn 3
hypercapnia 3
bitter taste 3
paresthesia 3
enuresis 3
Catch 3
abdominal discomfort 3
Wind 3
hypertonia 3
collapse 3
incoordination 2
bone pain 2
physical appearance 2
loss of taste 2
inanition 2
stridor 2
cyanosis 2
angina 2
hyperemesis 2
myoclonus 2
corpulence 2
numbness 2
hemiplegia 2
neck pain 2
Cushingoid 2
oliguria 2
myalgia 2
consciousness disturbance 2
dry eye 2
phosphatemia 2
epigastric pain 2
flank pain 2
low back pain 2
Cushingoid 2
wheezing 1
prostration 1
Osler's nodes 1
thinning 1
ENT 1
hoarseness 1
hot flashes 1
acute abdomen 1
personality change 1
Neuropathic pain 1
paraparesis 1
hyperesthesia 1
Mucosal hyperplasia 1
snoring 1
photophobia 1
Roth spots 1
physical exhaustion 1
splenomegaly 1
stomach pain 1
Pain and tenderness 1
exertional dyspnea 1
skin irritation 1
tense 1
Decreased activity 1
chronic constipation 1
nipple discharge 1
eds 1
Psychiatric symptoms 1
infant diarrhea 1
nipple discharge 1
tenesmus 1
syncope 1
intestinal bleeding 1
anosmia 1
despair 1
catatonia 1
hepatosplenomegaly 1
dysuria 1
dysesthesia 1
tinnitus 1
feeling depressed 1
arthralgia 1
pallor 1
dysosmia 1
bradykinesia 1
eye discharge 1
acidity 1
Fluctuation 1
forgetfulness 1
nasal congestion 1
sore throat 1
right upper quadrant pain 1
abdominal fullness 1
blurred vision 1
dry skin 1
chorea 1
spasticity 1
auditory hallucination 1
Skin symptoms 1
fever of unknown origin 1
excessive sweating 1
stomach distension 1
vertigo 1
tingling 1
muscle rigidity 1
Hyposexuality 1
more...
Drug
Cardiovasc 20
Nephron 13
CSF 13
Dermatol 10
Growth hormone 9
Glucagon 8
lysine 8
caffeine 8
Leaf 8
Portal 7
Growth hormone 7
ascorbate 6
EE2 6
Sulpiride 6
citric acid 5
Dial 5
vitamin E 5
Modafinil 5
Histamine 4
Diurnal 4
DHT 4
Serum albumin 4
Liraglutide 4
Dexfenfluramine 4
ICI 4
DHT 4
Rimonabant 4
PTH 4
Asn 3
lactose 3
GHRP 3
Monosodium glutamate 3
9-THC 3
Albumin 2
Fluconazole 2
AmBisome 2
Spectrum 2
PPA 2
Nephron 2
niacin 2
ENT 2
Monit 2
Cimetidine 2
Clonidine 2
Gel 2
Vitamin B12 2
Glycerol 2
Fructose 2
Periactin 2
ROS 2
Cimetidine 2
CTX 2
Lantus 1
Triad 1
Zonisamide 1
Amoxapine 1
Anafranil 1
Ranitidine 1
Omeprazole 1
Dexon 1
ABC 1
DBS 1
Luteinizing 1
Morphine sulfate 1
CMNX 1
Sandostatin 1
HCH 1
Insulin detemir 1
Namenda 1
Itraconazole 1
Mazindol 1
NVP 1
7-Nitroindazole 1
LMOX 1
Trilostane 1
Estrogens 1
Alanine 1
linolenate 1
Humulin 1
EPA 1
Sodium propionate 1
Potassium carbonate 1
Naprosyn 1
Sandostatin 1
Brofaromine 1
Spectrum 1
MAP 1
Methylprednisolone 1
Anafranil 1
L-tyrosine 1
DPA 1
Ramipril 1
Frontal 1
ampicillin 1
Everolimus 1
Tao 1
Agomelatine 1
Zaltoprofen 1
IPM 1
Terramycin ophthalmic 1
Corn oil 1
RAL 1
CMX 1
Sodium acetate 1
MOF 1
CDP 1
Ciglitazone 1
Ethanol 1
CET 1
Teduglutide 1
Kenyan 1
PCP 1
CPR 1
Vitamin K 1
Ritanserin 1
THF 1
Mirtazapine 1
CTX 1
DMI 1
Orphan 1
Coconut oil 1
Soybean oil 1
Bifidobacterium 1
CED 1
Butorphanol tartrate 1
Liposyn 1
Coumadin 1
Streptokinase 1
CCL 1
MIL 1
Adriamycin 1
Calcium gluconate 1
Award 1
Retinoic acid 1
Angiotensin II 1
IL-1ra 1
ROC 1
Penfluridol 1
Armodafinil 1
CTX 1
nitroglycerin 1
Kollidon 1
Ritalin 1
Metreleptin 1
ACT 1
Dihydro 1
Sandostatin LAR 1
Enprostil 1
Colombo 1
Prednisolone 1
Enzyme
AMP-activated protein kinase 35
lipoprotein lipase 25
protein kinase 20
mitogen-activated protein kinase 18
focal adhesion kinase 17
monoamine oxidase 17
alanine aminotransferase 16
superoxide dismutase 14
aspartate aminotransferase 13
alkaline phosphatase 12
lipase 12
AMPK 11
tyrosine hydroxylase 11
AMPK 11
glucokinase 11
ERK 10
acetyl-CoA carboxylase 10
phosphoenolpyruvate carboxykinase 10
phosphoenolpyruvate carboxykinase 10
phosphoenolpyruvate carboxykinase 10
cytochrome oxidase 9
catalase 9
trypsin 9
hormone-sensitive lipase 8
glucose-6-phosphatase 7
pyruvate kinase 7
BAT 7
ATPase 7
NO synthase 7
lactate dehydrogenase 7
renin 6
glutathione peroxidase 6
alpha-glucosidase 6
RNase 5
adenylate cyclase 5
DTA 5
hexokinase 5
RNase 5
11beta-hydroxysteroid dehydrogenase 5
CPT 4
glucose-6-phosphate dehydrogenase 4
ACE 4
cholinesterase 4
IKK 4
BIS 4
aldose reductase 3
ribonuclease 3
tryptophan hydroxylase 3
cholesterol acyltransferase 3
collagenase 3
phosphatidylinositol 3-kinase 3
ACS 3
LPL 3
asparaginase 3
furin 3
phosphorylase 3
phosphodiesterase 3
AST 3
complex I 3
alcohol dehydrogenase 3
diacylglycerol acyltransferase 3
reverse transcriptase 3
ribonuclease 3
ceruloplasmin 3
DNA methyltransferase 3
3-hydroxy-3-methylglutaryl-CoA reductase 3
sucrase 2
acetylcholinesterase 2
prolyl endopeptidase 2
ADH 2
pyruvate dehydrogenase 2
NOS 2
MAP 2
carbonic anhydrase 2
AMP-activated kinase 2
alpha-amylase 2
acyl-CoA oxidase 2
chalcone synthase 2
ornithine decarboxylase 2
guanylate cyclase 2
phosphofructokinase 2
NADPH oxidase 2
DOPA decarboxylase 2
glycerol-3-phosphate dehydrogenase 2
DAT 2
peroxidase 2
invertase 2
phosphoinositide 3-kinase 2
chymotrypsin 2
creatine kinase 2
ornithine transcarbamylase 2
NADPH oxidase 2
3-hydroxyacyl-CoA dehydrogenase 2
choline acetyltransferase 2
O-GlcNAc transferase 2
fatty-acid synthase 2
3-hydroxy-3-methylglutaryl coenzyme A reductase 2
glutathione S-transferase 2
glycerol-3-phosphate dehydrogenase 2
arginase 2
glutamate decarboxylase 1
xanthine oxidase 1
tyrosinase 1
glutathione reductase 1
TSO 1
acyl-CoA dehydrogenase 1
diamine oxidase 1
pepsin 1
pyruvate dehydrogenase 1
phenol hydroxylase 1
PRE 1
thyroid peroxidase 1
caspase-3 1
p-nitrophenylphosphatase 1
lysozyme 1
ALA synthase 1
CDP-diacylglycerol synthase 1
argininosuccinate synthetase 1
neuraminidase 1
proteasome 1
ATP synthase 1
tyrosine aminotransferase 1
PDK1 1
PRA 1
ACAT 1
CPT 1
MEK 1
glycerophosphate acyltransferase 1
protein phosphatase 2A 1
calcineurin 1
citrate synthase 1
Alternating 1
CYP7A1 1
glucose oxidase 1
thromboplastin 1
MDR 1
fatty acid desaturase 1
STR 1
proprotein convertase 1
subtilisin 1
GABA transaminase 1
aconitase 1
acyl-CoA dehydrogenase 1
monoacylglycerol lipase 1
PCP 1
CPN 1
Pla 1
deaminase 1
APC 1
plasmin 1
dopamine beta-hydroxylase 1
CPT 1
urokinase-type plasminogen activator 1
endonuclease 1
hyaluronidase 1
SST 1
carboxypeptidase E 1
ALDH 1
oligopeptidase B 1
protein kinase C 1
more...
Compound
glucose 783
Dec 403
Clin 361
water 269
galactose 110
Insulin 101
oxygen 94
nitrogen 94
5-HT 91
DNA 72
sodium 69
calcium 56
DSM 53
creatinine 50
glutamate 44
His 43
urea 43
arginine 42
STZ 41
GABA 40
GABA 40
noradrenaline 34
zinc 34
glycerol 31
ACTH 31
potassium 31
tyrosine 30
salt 29
nitric oxide 29
ethanol 28
Parenteral 27
ATP 26
GDP 26
phosphate 26
leucine 26
sulfate 25
acetate 24
methionine 22
tryptophan 21
tryptophan 21
silver 21
CO2 19
NH2 19
tryptophan 19
tryptophan 19
cAMP 18
Sucrose 18
iron 17
alloxan 17
alpha-MSH 16
glutamine 16
serine 16
phosphorus 16
Phe 16
Olanzapine 14
CoA 14
alanine 14
Dopamine 13
hydrogen 13
NADP 13
barium 13
Naltrexone 12
lysine 12
threonine 12
TNF 12
Thyroid 11
Norepinephrine 11
vitamin D 10
hydroxyindoleacetic acid 10
valine 10
Gly 10
DAMGO 10
FFA 9
AMP 9
copper 9
Nicotine 9
5-HIAA 9
5-hydroxytryptophan 9
nicotinamide 8
Glucagon 8
Ile 8
Fenfluramine 8
gamma-aminobutyric acid 8
Morphine 8
cysteine 8
Oxytocin 8
2-Deoxy-D-glucose 8
caffeine 8
palmitic acid 7
Cortisol 7
HCl 7
Corticosterone 7
nitrate 7
PEG 7
GSH 7
vanadium 7
ammonia 7
Neuronal 7
xylose 7
Cholesterol 7
aldosterone 7
GSH 7
Naloxone 7
DBA 7
Diazepam 7
isoleucine 6
Estradiol 6
DBA 6
AEA 6
L-DOPA 6
acetic acid 6
GTP 6
hydrazine 6
Diabetol 6
Cardiol 6
oxalate 6
DBA 6
isoleucine 6
SDS 6
palmitic acid 6
MSG 6
Topiramate 5
TCA 5
PAS 5
DMN 5
Resveratrol 5
Cocaine 5
TRH 5
Sodium 5
NAD 5
A 3 5
selenium 5
DTA 5
butyric acid 5
DOPAC 5
Retard 5
CPP 5
2,4-dichlorophenyl 5
butyric acid 5
malonyl-CoA 5
Acarbose 5
Adrenal 5
TSH 5
2,4-dichlorophenyl 5
carbonate 5
butyric acid 5
Estrogen 5
Metformin 5
pentose 5
cGMP 5
6-12 5
Estrogen 5
Dial 5
piperazine 5
PGE2 5
Metformin 5
Muscimol 4
Amphetamine 4
PMA 4
Amphetamine 4
more...