Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020505 (
hyperphagia
)
6,116
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Vascular accidents represent one of the most important causes of morbidity and mortality in France at the present time, and factors increasing the risk of such lesions are well documented: hypertension, smoking, and metabolic disorders (lipids, glucides, uric acid). Though genetic factors are definitely involved, most of them are acquired and related to our way of life, our type of civilisation, and, more particularly, to
overeating
and a sedentary life. Regular physical exercise of sufficient degree can considerably reduce the various factors which increase risk and, at the same time, diminish the frequency of these very serious vascular accidents.
Sem
Hop
PMID:[Athletic activities and prevention of vascular risk factors]. 21 96
Parenteral
hyperalimentation
and complete bowel rest reduce fistula output, and permit sufficient caloric and nitrogen intakes needed for healing. It corrects metabolic and nutritional deficiencies due to digestive fistulas, and allows spontaneous closure of fistulas in two out of three patients. If spontaneous healing is not obtained after six weeks of parenteral alimentation, surgical treatment may be undertaken more safety, as the patient will be in better nutritional condition.
Sem
Hop
PMID:[Parenteral hyperalimentation in the treatment of esophageal, gastric and intestinal fistulas (author's transl)]. 22 1
Too often neglected, dosage of phosphatemia should yet be kept on mind. The role of phosphorus in bone mineralization and regulation of acid-base balance is well known. Phosphorus is also an energy purveyor during numerous biologic reactions, and deep deprivation may lead to a lot of pathologic situations, sometimes severe. Mild hypophosphatemia is not rare and occurs in various clinical or therapeutic circumstances; deep hypophosphatemia is rather uncommon, occuring chiefly during
hyperalimentation
or realimentation of starving patients, especially alcoholics. Deep hypophosphatemia (by depletion or transfer) mainly induces clinical and pathological manifestations; they are subsequent to alterations of glucose metabolism, leading to a failure in ATP and 2,3 DPG synthesis. These metabolic events particularly explain muscular and hematological manifestations of hypophosphatemia. Phosphorus loading per os, or in severe cases intravenously corrects the biological abnormalities and improves clinical manifestations.
Sem
Hop
PMID:[Hypophysphatemia (author's transl)]. 624 3
Twenty-five patients with various forms of dyskinesia were given tiapride for three months. Maximal dosage was 900 mg per day. A double-blind trial of tiapride versus placebo showed significantly better results in the group given tiapride. The forms of dyskinesia which responded best to tiapride were the following: iatrogenic dyskinesia, tics (Gilles de la Tourette syndrome), and chronic chorea (Huntington disease). Patients with complex dyskinesia resulting from neonatal encephalopathy or vascular disease were not improved. The protocol used in l-dopa-induced dyskinesia is described. Changes in dyskinesia and "on-off" effect following variations in tiapride and l-dopa dosage are detailed. An unequivocal, although minor, tiapride-induced parkinson syndrome was recorded in a few patients. No instances of tiapride-induced dyskinesia or akathisia were seen. The other side-effects were either psychic (depression, drowsiness, agitation) or endocrinologic (menstrual disorders,
overeating
, galactorrhea).
Sem
Hop
1982 Mar 25
PMID:[Clinical trial of tiapride in patients with dyskinesia (author's transl)]. 628 45
This is a general survey of pertinent topics concerning female sterilization in France in question and answer format. Sterilization is not outdated as a result of modern contraception because now more women desire efficient contraception. There is no French law against female sterilization, but the case for men is not as clear. Examples of gynecologic, obstetrical, medical, genetic, psychosocial, and extramedical indications were listed. 5 types of tubal sterilization and 4 routes were described: mini-laparotomy and celioscopy are popular in France, but colpotomy and the inguinal route are rare. Sterilization is preferred immediately after delivery or in the puerperium. Failures range from 1:2000 for Irving procedure, to a maximum in those sterilized just after delivery. Hysterectomy is not recommended because of risk of neurosis. Tubal sterilization can be reversed in 27-75% of cases. Much discussion was devoted to psychological sequelae of sterilization in French women, such as frigidity, depression, guilt, regret, nervousness, cancerophobia,
overeating
, some of which occur in half of the patients. These frustrations were blamed on cultural and religious taboos. French physicians were urged not to sterilize women under 30, with fewer than 3 children, of Moslem, Jewish or Catholic faith, with poor acceptance of feminity, excessive maternal instinct, or poor marital adjustment. Male sterilization was not recommended, because the side effects of impotence and depression are unacceptable.
Sem
Hop
Paris 1972 Jun 20
PMID:[Female surgical sterilization]. 1233 4