Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
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Target Concepts:
Gene/Protein
Disease
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Query: UMLS:C0020505 (
hyperphagia
)
6,116
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Rapid growth of a transplantable insulinoma in rats over a 14 day period results in
hyperphagia
together with a selective increase in the weight and enteroglucagon (
GLI
) concentration of the small intestine. Measurement of serotonin concentrations by an HPLC/fluorometric method demonstrated an increase in blood (91%; p less than 0.05) and in extracts of colon (22%; p less than 0.05) but no change in extracts of the small intestine and caecum. The data support the hypothesis that the rise in enteroglucagon is related directly to the growth of the small intestine and is not a non-specific effect of
hyperphagia
.
...
PMID:Effect of a transplantable insulinoma upon serotonin concentrations in the intestine of the rat. 282 10