Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020505 (
hyperphagia
)
6,116
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Electrical stimulation of the ventral noradrenergic bundle (V-NA bundle) produced 3 types of responses in lateral hypothalamic neurons: IPSPs, a polysynaptic
EPSP
-IPSP sequence and antidromic spikes. The IPSPs were considered to be monosynaptic due to the fixed latencies seen at stimulus intensities. Iontophoretic application of an alpha-NA antagonist blocked only the presumed monosynaptic inhibition. Most of the glucose-sensitive neurons were inhibited by stimulation of the V-NA bundle. These results may account for the
hyperphagia
and obesity produced by selective lesions of the V-NA bundle.
...
PMID:Inhibitory action of the ventral noradrenergic bundle on the lateral hypothalamic neurons through alpha-noradrenergic mechanisms in the rat. 627 35
