Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020505 (hyperphagia)
 6,116 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

From December 1986 through July 1987, forty-one Groshong catheters were inserted in 38 patients with invasive gynecologic cancer for a cumulative total of 4170 days of patient use. (mean catheter indwelling time: 93 days; range: 3-300 days). A supraclavicular approach was used to cannulate the brachiocephalic vein in 31 patients. In 6 patients, the subclavian vein was cannulated via an infraclavicular approach, while 4 patients had the catheters placed via external jugular venous cutdown. Thirty-seven catheters were inserted at the bedside without fluoroscopy using the Seldinger technique and a peel-away catheter introducer sheath. A chest x-ray was used to confirm the right atrial position of the catheter. Major complications included two pneumothoraces, and three catheter-related cases of sepsis. A unique feature of the Groshong catheter is a pressure-sensitive two-way valve at the intravascular end, minimizing the potential for air embolism and back-bleeding. This eliminates the need for a heparin flush or external clamping, but permits blood sampling. Catheter insertion and maintenance procedures at bedside are simple, time saving, and cost effective. With the increasing use of continuous chemotherapy infusion protocols, use of vesicant drugs, hyperalimentation, and the need for outpatient therapy, we recommend early placement of the Groshong catheter in the oncology patient.
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PMID:Vascular access in gynecologic cancer using the Groshong right atrial catheter. 272 54

In order to clarify the clinical characteristics along with the practical care of home hospice care for gynecological cancer patients, we analyzed 37 terminally-ill gynecological cancer patients who died at home from July 1, 2003 through June 30, 2010, and these patients were compared with 762 non-gynecology cancer patients. The range of patients' ages with gynecological malignancies was statistically younger(p<0. 05)than that of the control patients, whereas the duration of home care and home death ratio did not show significant differences. As for medical treatment, the frequency of the management of nephrostomy was significantly higher in cases with gynecological malignancies. However, the frequencies of the usage of strong opioids, home oxygen therapy, home parenteral hyperalimentation, management of central venous port and indwelling bladder catheter showed no significant differences. There were patients, who needed special treatments by a gynecologist, with vesicovaginorectal fistula in one case, subcutaneous abscess probably caused by rectocutaneous fistula in one case, vaginal bleeding in one case and acute urinary retention treated by an emergent bladder puncture. By analyzing the focus problem lists of the total suffering at each clinical phase, in patients living longer than 15 days at home,(Kawagoe's classification in 1991)this did not show significant difference against the control group. In conclusion, gynecologic cancer patients were significantly younger than those with non-gynecologic malignancies, though not statistically significant, showing the tendency of short duration. Thus, in cases of gynecologic malignancies, it is important to take these characteristics into consideration.
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PMID:[Home hospice care for the patients with gynecological malignancies]. 2218 25