Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020505 (
hyperphagia
)
6,116
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Serum tyrosine concentration, Phe/Tyr scores and psychomotor/mental development scores were analysed in 32 children with
phenylketonuria
(
PKU
) and 39 with mild hyperphenylalaninaemia. Observation period included the first 6 years of life. Tendency to tyrosine deficiency was observed; stronger in dietary treated
PKU
patients than in those with mild hyperphenylalaninaemia. Statistically significant differences between patient groups were found only in 3 and 6 years old children (lower tyrosine values in
PKU
patients). It was observed that evaluation of Phe/Tyr score value might be usefull in differentiation between
PKU
and mild hyperphenylalaninaemia. Moreover, the above score may help in the evaluation of hypo- and
hyperalimentation
state in the course of dietary treatment. The level of tyrosine deficiency in the analysed patient groups did not influence their normal intellectual development.
...
PMID:[Serum tyrosine in children with phenylketonuria and mild hyperphenylalaninemia]. 1101 57
