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Query: UMLS:C0020505 (hyperphagia)
 6,116 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Elemental enteral alimentation (EEA) is an alternative to parenteral nutrition in patients with a functioning gastrointestinal tract and increased caloric requirements or in whom regular oral feeding is impossible or impractical. EEA is given by nasogastric, jejunostomy, or gastrostomy tube. It is useful in cases of short-gut syndrome, pancreatic disease, partial intestinal obstruction, colitis, neuropsychiatric cachexia, trauma, fistula, vascular insult, and renal and liver disease, as well as in patients being prepared for surgery or requiring hyperalimentation after surgery or abdominal irradiation. Strict attention must be paid to fluid and electrolyte status and to blood and urine glucose levels in patients receiving EEA. With use of a nasogastric tube, infection of the middle ear is a possible but uncommon complication.
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PMID:Meeting exceptional nutritional needs. 2. Elemental enteral alimentation. 10 Jul 74

Five newborn girls presented with small intestinal obstruction and microcolon and a giant bladder (megacystis). Organic causes of obstruction were not found, and the gastrointestinal tract failed to function after appropriate diversion. Two died in the postoperative period, two lived several months on central venous hyperalimentation, and one died at 34 months of age following chronic though intermittent hyperalimentation. Pathologic studies showed an abundance of ganglion cells in both dilated and narrowed areas of intestine; the combined small bowel-colon length was one-third of normal in the absence of an evident obstructive or vascular insult. The five patients represent the most severe manifestation of defective intestinal peristalsis in a larger group of distended newborns in whom organic gastrointestinal obstruction is not found. Treatment with central venous hyperalimentation may sustain life, and some patients eventually recover gastrointestinal function. The hypoperistalsis is largely refractory to pharmacologic treatment; its cause is unknown.
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PMID:Megacystis-microcolon-intestinal hypoperistalsis syndrome: a new cause of intestinal obstruction in the newborn. Report of radiologic findings in five newborn girls. 17 39

Superior mesenteric artery syndrome is a rare cause of upper intestinal obstruction in both adults and children. Sixteen children with severe traumatic brain injury and spastic quadriparesis developed small intestinal obstruction while undergoing a rehabilitation programme between 1981 and 1990. Five patients met the roentgenographic diagnostic criteria. The presenting symptom was post-prandial bilious vomiting. The mean age was 13 (10-16) years. The mean time clapsed from injury to diagnosis was 53 days and from rehabilitation admission to diagnosis 22 days. The mean delay in diagnosis after onset of symptoms was 4 days. All patients were of disproportionately lower body weight in relation to height, with a mean weight loss of 7 kg. The mean percentile for weight was 18 and height 58, with a difference of 30 between height and weight percentiles. The patients were receiving nasogastric or gastrostomy tube feedings at the onset of the symptoms. All patients were treated non-surgically with gastric aspiration, nasojejunal or gastrojejunal feeding by passing a feeding tube distal to obstruction. No patient required intravenous hyperalimentation. There was no recurrence in any patient during the follow-up period of 1-5 years. Though rare, superior mesenteric artery syndrome can develop in brain-injured children with spastic quadriparesis, prolonged recumbency and recent weight loss. Increased awareness of occurrence of this condition and timely management will decrease morbidity and complications that may interfere with recovery.
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PMID:Superior mesenteric artery syndrome: an unusual cause of intestinal obstruction in brain-injured children. 163 68

Superior mesenteric artery (SMA) syndrome is a rare cause of small bowel obstruction in both adult and pediatric populations. Of 14 patients with the diagnosis from 1979 to 1987, eight had confirmatory upper gastrointestinal studies and were able to be followed for an average of 32 months. All eight were of similar age (range, 14.2 to 19 years), body build (asthenic), and clinical presentation. The presentation included nausea and intermittent, voluminous, bile-stained vomiting, despite intervening periods of normal appetite and bowel sounds. The average delay in diagnosis was five days. Nasogastric drainage and intravenous fluids were the mainstay of treatment and were successful in every case. Fifty percent of the patients had more than one episode requiring treatment; each episode resolved with simple treatment. Two of three patients with body casts required cast removal. No patient required intravenous hyperalimentation, removal of spinal instrumentation, or abdominal surgery to relieve the obstruction. Three of the eight patients had not had spinal surgery or cast immobilization.
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PMID:Superior mesenteric artery syndrome in pediatric orthopedic patients. 229 37

This conference concerns economic, psychosocial, preventive, and medical aspects of the care of an indigent, unemployed, 22-year-old mother of three who died of an invasive, large cell, nonkeratinizing cervical cancer 35 months after her last Pap smear, 19 months after the onset of vaginal discharge, 12 months after consulting a physician, 10 months after an exploratory laparotomy, nine months after initiation of radiation therapy, five months after performance of a colostomy, four months after initiation of chemotherapy, and three months after treatment of small bowel obstruction with hyperalimentation and resection. We discuss the cost effectiveness of preventive programs.
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PMID:Cervical cancer. 309 98

A 61-year-old black woman was admitted with intermittent small bowel obstruction following multiple therapies for recurrent ovarian carcinoma. Conservative enteric therapy with central hyperalimentation was begun prior to surgical intervention. After approximately 3 wk without resolution, surgical bypass of the obstructed area was performed for palliation. With the return of bowel function, continuous enteral feeding was utilized. During placement of enteral feeding tube, the proximal end spontaneously retracted into the patient's nasal cavity with associated patient distress. After some difficulty, the feeding tube was removed. Simple design modification of the proximal portion of the nasogastric feeding tube should prevent such complication. The addition of "wings" to the proximal end should be considered as a modification to prevent similar occurrences.
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PMID:Intranasal retraction of nasogastric feeding tube: case report and suggestion for design modification. 391 3

Meteorism might be a symptom of organic intestinal obstruction, which needs surgical treatment in most cases. However it is often a functional phenomenon. It may be produced by aerophagy, followed by sonor, non fetid flatulence. Large amounts of gas are produced by the contact of gastric acidity with alcaline pancreatic secretion and by enzymatic digestion of food. Most of these gases are absorbed by the intestine and exhaled. In the colon bacterial fermentation and putrefaction produce fetid gas which is expulsed as flatus. Overeating, bacterial invasion of the small intestin, inflammatory and circulatory disturbances of the small bowel and obstipation favour meteorism. The treatment depends of the origin of meteorism.
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PMID:[Pathogenetic basis and therapeutic management of meteorism (author's transl)]. 611 Mar 77

Seventy-three patients with small bowel obstruction due to metastatic carcinoma were seen in the years 1960 to 1979. Twenty-nine patients were seen in the first decade and 44 patients in the second. The most common primary tumor causing metastatic small bowel obstruction was colonic carcinoma, followed by gastric carcinoma. Plain x-ray examinations supplemented by an upper gastrointestinal series with small bowel follow-through were the most useful diagnostic tests. Seventy per cent (51/73) of these patients were initially treated with intravenous fluids and gastrointestinal decompression using a short (32/51) or long (19/51) tube. In eight of 51 patients, nasogastric decompression relieved the obstruction, but in all but one of these patients symptoms and signs of obstruction recurred promptly after tube removal. At laparotomy, the majority of patients underwent either a bypass procedure or resection. The mean survival for the patients bypassed varied from four to seven months; for those that had resection it varied from five to nine months. The mortality rate was high--41 per cent in the first decade and 25 per cent in the second. Of the last 12 patients, eight received hyperalimentation before and after surgery. The operative mortality rate was 12.5 per cent and the mean survival was eight months. It is concluded that: 1) Colonic carcinoma is the most common primary tumor causing metastatic small bowel obstruction. 2) Tube decompression is rarely effective and surgical relief is necessary in the vast majority of cases. 3) Operative mortality has been reduced, partially because of more vigorous support, i.e., hyperalimentation, but the mean duration of survival has not changed significantly.
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PMID:Surgical palliation of small bowel obstruction due to metastatic carcinoma. 616 83

The authors report a series of 16 total cystoprostatectomies with only one postoperative death. Eleven of these operations, performed with the intention of achieving a complete cure, were carried out after flash radiotherapy of 1.000 rads on the day before surgery and were completed by uretero-sigmoidostomy. The five palliative operations were completed by direct bilateral cutaneous ureterostomy, the patients having received preoperative radiotherapy of 5 to 6,000 rads. The authors attribute the low postoperative mortality to the value of the energy and protein provided by parenteral hyperalimentation which made it possible to administer to the patient from the day after surgery onwards 1,400 to 2,600 calories per day (60% as carbohydrate and 40% as lipids) and 1 gram/kilo of protein per day. Infusion catheters were inserted under strictly aseptic conditions on the day prior to surgery into the deep main veins by percutaneous puncture of a subclavian vein or cutdown of an external jugular vein, and were kept in place until such time as oral alimentation could ensure an equivalent intake. For the 11 patients undergoing curative surgery, weight loss at the time of discharge was no more than 1 to 2 kilos, a figure to be contrasted with the 7 to 8 kilos before the use of parenteral hyperalimentation. The only death occurred amongst the 5 patients undergoing palliative surgery. In the latter group, the authors were stuck by the uncomplicated postoperative course, and the control of complications such as intestinal obstruction or bacteraemia which was obviously better in veiw of the maintenance of the calorie reserves of the body. All parenteral hyperalimentation was administered in the form of commercial solutions and emulsions.
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PMID:[Parenteral hyperalimentation and cystoprostatectomy for carcinoma of the bladder (author's transl)]. 679 25

Two children with nonfamilial chronic intestinal pseudoobstruction are reported. Both had no family history. They had an exploratory laparotomy to rule out mechanical intestinal obstruction, and required long-term parenteral nutrition to obtain sufficient nutrients. These two children had dilatation of the whole length of the small intestine, which differs from short segmental dilatation (megaduodenum) in patients with familial chronic intestinal pseudoobstruction. There were also differences in the histology of the gastrointestinal tract between these two patients although they had similar clinical manifestations. Both patients died from cardiac arrest, one after 2 years and the other after 4 months on long-term parenteral hyperalimentation. At autopsy, heart examination was normal in one patient, and a small infarction (0.4 mm diameter) was found in the other. Although mild hypokalemia was found in one case, and mild hyperkalemia in the other, the cause of cardiac arrest in these two children is not known.
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PMID:Cardiac arrest in two children with nonfamilial chronic intestinal pseudoobstruction on total parenteral nutrition. 682 Nov 6


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