Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020505 (hyperphagia)
 6,116 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Urinary incontinence affects up to 43 per cent of acute care patients. Toileting is a function of intact bladder, sphincters, and nervous system. Five types of incontinence are stress, urge, reflex, total, and functional. Problems affecting patients in acute care are: 1. Diagnostic studies 2. Treatments--for example, intravenous fluids, hyperalimentation, medications, catheters 3. Bedrest 4. Restraints 5. Pain 6. Iatrogenic conditions 7. Environment Assessment includes a specific history and physical examination, focused on previous episodes of incontinence, functional ability, and cognitive status. Management includes scheduled fluid intake and toileting, manipulation of the environment, and attention to orientation and psychological factors. The treatment of fecal incontinence in the hospital elderly includes: 1. Assessment of incontinence and contributing factors; 2. Bowel regimen and environmental assists for persons with periodic incontinence; 3. Treatment of diarrhea or constipation; and 4. Protection of perineal skin from stool exposure.
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PMID:Continence issues in acute care. 277 95

A case of traumatic sacro-iliac disruption with severe perineal rupture and ano-rectal incontinence by total unilateral laceration of the levator ani muscle is reported. The use of parenteral hyperalimentation as a "medical colostomy" has been successfully applied maintaining the patient's nutritional status while healing of the wound occurred. This gives the surgeon an option for the management of such a severe sphincter's laceration: without resorting to preliminary colostomy. The general management of patients with perineal and rectal trauma is reviewed. The prerequisite of bone fracture consolidation prior soft tissue repair is emphasized. Progressive recovery of ano-rectal continence is demonstrated by repeated ano-rectal manometry.
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PMID:[Perineal rupture and anorectal incontinence with traumatic sacroiliac dislocation. Treatment and functional results]. 641 17

We report a kindred with three cases of dementia. The proband presented with forgetfulness and personality changes at age 56, followed shortly thereafter by behavioral dyscontrol, hyperphagia, hypersexuality, delusions, illusions, disinhibition and double incontinence. Neuroimaging studies were consistent with frontotemporal dementia (FTD). In one allele, an arginine insertion at codon 352 in the presenilin 1 (PSEN1) gene was identified; no mutation was identified in the amyloid precursor protein or tau genes. We conclude that the clinical features of the Kluver-Bucy syndrome and FTD can be associated with PSEN1 mutations. Furthermore, presenilin analyses may be helpful to characterize kindreds with familial dementing illnesses regardless of the phenotype, particularly if no tau mutation is present.
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PMID:Familial frontotemporal dementia associated with a novel presenilin-1 mutation. 1205 27