Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020505 (
hyperphagia
)
6,116
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Night eating syndrome (NES) is an
eating disorder
characterised by the clinical features of morning anorexia, evening
hyperphagia
, and insomnia with awakenings followed by nocturnal food ingestion. The core clinical feature appears to be a delay in the circadian timing of food intake. Energy intake is reduced in the first half of the day and greatly increased in the second half, such that sleep is disrupted in the service of food intake. The syndrome can be distinguished from bulimia nervosa and binge eating disorder by the lack of associated compensatory behaviours, the timing of food intake and the fact that the food ingestions are small, amounting to repeated snacks rather than true binges. NES also differs from sleep-related
eating disorder
by the presence of full awareness, as opposed to parasomnic nocturnal ingestions. NES is of importance clinically because of its association with obesity. Its prevalence rises with increasing weight, and about half of those diagnosed with it report a normal weight status before the onset of the syndrome. The recognition and effective treatment of NES may be an increasingly important way to treat a subset of the obese population. Treatment of the syndrome, however, is still in its infancy. One clinical trial has reported efficacy with the SSRI sertraline. Other treatments, such as the anticonvulsant topiramate, phototherapy and other SSRIs, may also offer future promise.
...
PMID:Night eating syndrome : diagnosis, epidemiology and management. 1633 42
Eating disorders
represent a continuum in the pathological feeding behaviour with anorexia and severe malnutrition as one extreme and with psychogenic
overeating
and atypical forms of
Eating disorders
accompanied with obesity as the second extreme. World-wide epidemical spread of obesity and consequences of obesity frequently results in neglection of eating disorders problems and in apprehension of obesitologists that the
Eating disorders
prevention could challenge their efforts in the prevention of obesity. Because the scientific approach can enrich both fields, possibilities to improve cooperation between them in the fields of clinical and preventive care are studied. They are based on the recognition of common risk factors and in the more effective and aimed prevention and therapy. Some new discoveries in this field are discussed.
...
PMID:[New questions and their solution in eating disorders]. 1663 74
A preliminary exploration of the etiological factors that may contribute to the relationship between
eating disorder
symptoms and personality disorder traits is reported based on a general-population twin sample of 221 pairs. Symptoms of
eating disorder
, assessed using the Health Information Questionnaire (HIQ), formed 3 factors: Concern for
Overeating
, Purging, and Body Mass Index (BMI). Modest genetic influences were observed on Concern for
Overeating
, possible non-additive genetic effects on Purging, and substantial additive genetic effects for BMI. Substantial nonshared environmental effects occurred with the Concern with
Overeating
and Purging scales, and common environmental effects were noted for the Concern with
Overeating
scale. Personality disorder traits were assessed using the Dimensional Assessment of Personality Pathology-Basic Questionnaire (DAPP-BQ). Phenotypic, genetic, and environmental correlations between the HIQ scales and higher-order personality disorder factors were modest. The strongest relationship was between Concern with
Overeating
and Emotional Dysregulation. Relationships among DAPP-BQ basic trait scales and
eating disorder
symptoms were modest and relatively non-specific. The strongest relationships were with the Concern with
Overeating
scale. Purging also showed a modest relationship with affective lability and self-harm.
...
PMID:Etiological relationships between eating disorder symptoms and dimensions of personality disorder. 1686 29
The study examined to what extent emotional eating, restrained eating, and bulimic tendencies are found together in naturally occurring groups, and whether these groups differ in terms of the psychological characteristics relevant to eating disorders. One hundred twenty-seven normal-weight women filled in The Dutch Eating Behavior Questionnaire, The Eating Attitudes Test, The
Eating Disorder
Inventory, and five measures of psychological well-being. Cluster analysis revealed three dieter subgroups (Normal Dieters, Emotional Dieters, and Bulimic Dieters) and one nondieter group. The results showed that only some restrained eaters were emotional eaters and that only some emotional eaters had bulimic tendencies. In addition, emotional and bulimic dieters differed from nondieters more strikingly in terms of
eating disorder
psychopathology and low psychological well-being than normal dieters did. The results suggest that emotional eating is not responsible for
overeating
only but may, in concert with chronic dieting, also relate to the general psychopathology found to underlie eating disorders.
...
PMID:Emotional eating and eating disorder psychopathology. 1686 44
This study examined the clinical significance of the loss of control
over eating
as a key component of eating disorders. It investigated the association of eating-related psychopathology and general psychopathology with objective bulimic episodes (OBEs; experiencing a loss of control while consuming large amounts of food) and subjective bulimic episodes (SBEs; experiencing a loss of control while consuming small/moderate amounts). A community sample of 81 women with a range of disordered eating was recruited: binge-
eating disorder
, bulimia nervosa, subclinical eating disturbances, or no eating disorders. They were interviewed using the
Eating Disorder
Examination and completed measures of eating-related and general psychopathology. Both OBE and SBE frequencies correlated significantly with measures of eating-related and general psychopathology, and no significant differences were found between the magnitudes of the correlations with either binge episode type. SBE frequency significantly and independently predicted global
eating disorder
psychopathology. The loss of control
over eating
, without consuming large amounts of food, was as closely associated with specific
eating disorder
psychopathology and general mental health as were traditionally defined OBEs. SBEs may be an important target of treatment and should be considered for future diagnostic classifications of eating disorders.
...
PMID:Loss of control over eating reflects eating disturbances and general psychopathology. 1722 99
Night eating syndrome (NES), an
eating disorder
that has been linked to obesity, was first described in 1955. It occurs when the normally synchronous patterns of energy intake and sleep become disrupted; the result of this dysynchrony is a relative phase delay between the disordered eating patterns and the normal sleep-wake cycles. Although specific criteria for NES have not yet been validated, the characteristic associated behaviors are evening
hyperphagia
, morning anorexia, and insomnia. This article reviews NES prevalence, behavioral and neurohormonal manifestations of this disorder, criteria for its differential diagnosis, and current treatment options.
...
PMID:Night eating syndrome. 1772 63
Individuals with Prader-Willi syndrome have
hyperphagia
, a characteristic
eating disorder
defined by a marked delay in the satiety response when compared to controls. This
eating disorder
has been particularly difficult to control. The authors taught and evaluated effectiveness of regular exercise alone, regular exercise plus healthy eating, and mindfulness-based strategies combined with exercise and healthy eating to an adolescent with this syndrome. Mindfulness-based strategies included mindful eating, visualizing and labeling hunger, and rapidly shifting attention away from hunger by engaging in Meditation on the Soles of the Feet. On average, when compared to baseline levels, there were decreases in weight with regular exercise and exercise plus healthy eating, but the most consistent and sustained changes were evidenced when mindfulness training was added to exercise and healthy eating. The adolescent continued using the mindfulness health wellness program and further reduced his weight during the 3-year follow-up period.
...
PMID:A mindfulness-based health wellness program for an adolescent with Prader-Willi syndrome. 1828 4
A summary of the epidemiology, etiology and therapy of obesity is given with special emphasis on psychosomatic aspects. Overweight and obesity are widespread and go hand in hand with an increased health risk. The etiology of obesity is multifactorial based on gene/environment interactions;
hyperalimentation
and physical inactivity, as an expression of the rapid technical advancements within the past decades, have, however, had a decisive influence on the pandemic spreading of obesity. The prevalence of mental disorders is increased particularly in obese women. Although phylogenetically of relevance, an environment that associates slimness with beauty, health, physical and mental proficiency leads to a stigmatization of the obese. The results are mental symptoms and disorders. On the contrary, mental problems up to and including the full clinical picture of mental disorders may lead to changes in eating and exercise behaviour, the result of which may be a sustained positive energy balance with overweight and obesity. The success of conservative weight reduction measures in obesity is inadequate. Surgical measures are more successful, but they are only indicated for severe obesity. The psychosomatic and psychotherapeutic approach to overweight and obesity is multifactorial and indispensable. Obesity is not an
eating disorder
; it may, however, be the result of
hyperalimentation
into which pathogenetic and mental factors have been incorporated.
...
PMID:[Obesity is more than an eating disorder--the multidimensional perspective of a pandemia]. 1832 41
This study was designed to document
eating disorder
symptoms in a well-defined sample of patients with bipolar disorder and to evaluate the relationship of current loss of control
over eating
(LOC) to demographic and clinical features hypothesized to characterize bipolar patients at risk for disordered eating. Eighty-one patients enrolled in the Bipolar Disorder Center for Pennsylvanians provided demographic information and completed the Structured Clinical Interview for DSM-IV Axis I Disorders. The
Eating Disorder
Examination was administered by independent clinicians to evaluate current and lifetime
eating disorder
symptomatology. Twenty-one percent of participants met DSM-IV criteria for a lifetime
eating disorder
, and 44% reported a history of LOC. Patients who endorsed weekly LOC during the past six months (n=18) were heavier, had more atypical depressive symptoms, and were more likely to have a lifetime substance use disorder compared to patients in the rest of the sample (n=63). These findings indicate that
eating disorder
symptoms are prevalent in patients with bipolar disorder and are associated with obesity and other psychiatric morbidity. Screening for eating disorders in bipolar patients is warranted, as intervention may minimize distress and improve treatment outcome.
...
PMID:Prevalence and correlates of eating disorder co-morbidity in patients with bipolar disorder. 1878 43
This study examined the association between loss of control and
eating disorder
psychopathology in a community sample of women of Hispanic origin. Seventy-seven monolingual Spanish-speaking Latinas recruited from the community were administered the Spanish language version of the
Eating Disorders
Examination (S-EDE). Latinas who reported regular (at least once weekly) loss of control-through objective bulimic episodes (OBEs) and/or subjective bulimic episodes (SBEs)-were compared with Latinas who did not report regular loss of control. Latinas who reported LOC did not differ significantly from Latinas who denied LOC in age, current body mass index, or highest adult weight. Latinas who reported LOC had significantly more frequent weight cycling and significantly higher scores on all S-EDE subscales. The findings suggest that regular loss of control
over eating
-regardless of the amount of food consumed-may be a marker for the presence of
eating disorder
psychopathology.
...
PMID:Loss of control over eating is associated with eating disorder psychopathology in a community sample of Latinas. 1892 15
<< Previous
1
2
3
4
5
6
7
8
9
10
Next >>