Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020500 (hyperoxaluria)
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Human Gene/Protein
Sulfate anion transporter 1 15.1
L-alanine:glyoxylate aminotransferase 12.9
alanine-glyoxylate aminotransferase 12.6
SLC26A6 12.5
CFEX 12.4
GRHPR 12.4
sulfate anion transporter 12.3
AGXT 12.3
PH1 11.6
PRODH2 11.6
SAT-1 11.5
serine:pyruvate aminotransferase 11.2
Alanine-glyoxylate aminotransferase 11.1
Alanine:glyoxylate aminotransferase 11.1
NaDC-1 11.1
CFHR4 11.0
alanine:glyoxylate aminotransferase 11.0
major histocompatibility class II antigen 10.8
nuclear pore complex protein 10.7
hydroxypyruvate reductase 10.6
fetuin B 10.6
RASSF7 10.4
Kynurenine aminotransferase 10.3
DTDST 10.3
PH2 10.2
SLC26A5 10.0
glycolate oxidase 9.5
Glycolate oxidase 9.5
AGT1 9.4
NaSi-1 9.1
bikunin 9.1
VDDR 9.0
ATP6V1B1 8.9
PAT1 8.9
PH3 8.8
inter-alpha 8.7
CLC-5 8.6
GOX 8.5
LRRC8A 8.5
PolB 8.5
X-linked adrenoleukodystrophy 8.5
PEX2 8.4
PEX1 8.4
CFHR1 8.4
anion transporter 8.3
OCRL 8.3
AGT 8.3
OCRL1 8.2
A transferase 8.1
tenascin-X 8.0
AO2 7.9
SAT1 7.8
HSPG 7.8
OPN 7.7
LRC 7.5
p38 protein 7.5
gastric lipase 7.4
anion exchanger 7.4
ALD 7.2
NRK 7.2
KIM-1 7.2
NADPH oxidase 1 7.2
ED1 7.1
msrA 7.1
DCD 7.1
HPT 7.1
HK2 7.0
UTI 7.0
FSGS 6.9
HYP 6.9
Tamm-Horsfall glycoprotein 6.9
MASCOT 6.8
oxoglutarate 6.7
TCTP 6.7
osteopontin 6.7
BSC-1 6.6
prestin 6.6
intestine, liver 6.6
BMPR2 6.6
EXP 6.5
GLA 6.5
DNA polymerase gamma 6.5
NOX1 6.4
translationally controlled tumor protein 6.3
beta-lyase 6.3
TIS) 6.3
nuclear factor (erythroid-derived 2)-like 2 6.3
fructokinase 6.3
AMBP 6.3
pentraxin 3 6.2
alpha-enolase 6.1
Kelch-like ECH-associated protein 1 6.1
HUS 6.1
CgA 6.1
NALP3 6.1
ARB 6.1
Peroxisome proliferator-activated receptor 6.1
proximal tubule 6.0
TRAIL-R2 6.0
PSF 6.0
HPR 6.0
non-active 6.0
LIM domain 5.9
ARNT 5.9
RTA 5.9
acyl-CoA oxidase 5.9
alpha-ketoglutarate dehydrogenase 5.8
HC1 5.8
inorganic pyrophosphatase 5.8
transketolase 5.8
CD206 5.8
matrix Gla protein 5.7
ATG7 5.7
complement factor H 5.7
PKD2 5.6
PK1 5.6
chronic renal failure 5.6
PXR 5.6
N-acetyl-beta-glucosaminidase 5.6
leukocyte common antigen 5.5
INI1 5.5
POP 5.5
Transporter 5.5
DCF 5.4
N-acetyl-beta-D-glucosaminidase 5.4
BMP-7 5.4
GFR 5.4
p47phox 5.3
EGR-1 5.3
transporter 1 5.3
gamma-glutamyl transpeptidase 5.3
GBM 5.3
TNF-related apoptosis-inducing ligand 5.2
parathormone 5.2
Glutathione peroxidase 5.2
S100A9 5.2
Phospholipase A2 5.2
glutamate pyruvate transaminase 5.1
CPD 5.1
Superoxide dismutase 5.1
purinergic receptor 5.1
PKD1 5.1
annexin II 5.1
carbonic anhydrase II 5.0
NOX4 4.9
ASC 4.9
CX3CR1 4.9
NOX2 4.9
renal amyloidosis 4.9
TNFR2 4.9
parathyroid hormone 4.9
MCP-1 4.9
Smad7 4.9
version 3 4.9
AT1R 4.8
Klotho 4.8
NRF2 4.8
lactate dehydrogenase 4.8
CD95L 4.8
TTP 4.8
more...
Disease
hyperoxaluria 15.1
Hyperoxalemia 14.5
Enteric hyperoxaluria 14.5
Secondary oxalosis 14.0
Oxalate nephropathy 13.7
primary hyperoxaluria 12.7
oxalosis 12.3
Peroxisomal disorders 11.9
hypercalciuria 11.3
VDD1 11.3
Henoch-Schoenlein nephritis 11.3
nephrocalcinosis 11.1
glycinuria 11.1
Proximal renal tubular acidosis 10.9
nephrolithiasis 10.9
cystinuria 10.9
urolithiasis 10.8
Rhizomelic chondrodysplasia punctata 10.5
Idiopathic hypercalciuria 10.1
sponge kidney 9.9
HP2 9.9
steatorrhea 9.9
Distal renal tubular acidosis 9.9
vitamin B6 deficiency 9.8
uricosuria 9.8
hypophosphaturia 9.7
Acute renal insufficiency 9.7
cystathioninuria 9.3
ureterolithiasis 9.1
blind loop syndrome 9.1
Refsum disease 8.9
Zellweger syndrome 8.9
renal tubular acidosis 8.9
Dent's disease 8.8
phosphaturia 8.7
HP1 8.7
Fitz-Hugh-Curtis syndrome 8.6
chronic urinary tract infection 8.4
tooth resorption 8.4
sprue 8.3
Pneumatosis cystoides intestinalis 8.2
MPGN 8.0
hyperglycinemia 7.9
malabsorption 7.9
staghorn calculus 7.8
Rasmussen encephalitis 7.7
tropical sprue 7.7
chondrodysplasia 7.6
Lowe syndrome 7.6
Malassez 7.5
Inborn errors of metabolism 7.4
ileocolitis 7.4
short bowel syndrome 7.4
ALD 7.3
Recurrent disease 7.3
interstitial nephritis 7.2
Bartter's syndrome 7.1
primary hyperparathyroidism 7.1
asthmatic bronchitis 7.1
radiculitis 7.0
MIN 7.0
MIN 7.0
morbid obesity 6.9
magnesium deficiency 6.9
cystinosis 6.9
osteodystrophy 6.8
urosepsis 6.7
pyuria 6.7
anuria 6.6
metabolic disorder 6.6
potassium deficiency 6.6
regional enteritis 6.5
renal failure 6.5
AMN 6.4
Lowe 6.4
thiamine deficiency 6.4
uropathy 6.3
chronic glomerulonephritis 6.3
enzyme deficiency 6.3
hyperuricemia 6.2
urinary tract infection 6.2
enteropathy 6.2
hypervitaminosis 6.1
EDA 6.1
polyarthralgia 6.0
recurrent urinary tract infection 6.0
CNF 6.0
Fanconi syndrome 6.0
excessive drinking 5.9
metabolic alkalosis 5.9
renal disease 5.9
hyperparathyroidism 5.9
HYP 5.8
Focal segmental glomerulosclerosis 5.8
tyrosinemia 5.8
tubular necrosis 5.8
Alport syndrome 5.8
hemangioendothelioma 5.7
failure to thrive 5.7
ATN 5.7
acute tubular necrosis 5.6
hyperphosphatemia 5.6
chronic renal failure 5.5
nephrosis 5.5
pancreatic insufficiency 5.5
Hyperplasia 5.5
CAN 5.5
osteomalacia 5.5
Wernicke's encephalopathy 5.5
multiple disorders 5.5
chronic pancreatitis 5.4
nephrosclerosis 5.4
acute renal failure 5.4
amaurosis 5.4
renal insufficiency 5.4
hypercalcemia 5.3
calcinosis 5.3
acute intermittent porphyria 5.3
renal hypertension 5.3
vitamin E deficiency 5.3
night blindness 5.2
leukodystrophy 5.2
hydronephrosis 5.2
Autosomal dominant polycystic kidney disease 5.2
HCA 5.2
maple syrup urine disease 5.2
zygomycosis 5.2
Crohn's disease 5.2
hepatorenal syndrome 5.1
membranous nephropathy 5.1
mild mental retardation 5.1
TAS 5.1
protein deficiency 5.0
gastrointestinal disease 5.0
dermatitis herpetiformis 5.0
glomerulosclerosis 5.0
hemolytic uremic syndrome 5.0
polycystic kidney 4.9
megacolon 4.9
vitamin B12 deficiency 4.9
carcinoid syndrome 4.8
renal osteodystrophy 4.7
proteinuria 4.7
Fanconi 4.7
nephritis 4.7
bacteriuria 4.6
ileus 4.6
porphyria 4.6
TTP 4.6
bone disease 4.5
pyelonephritis 4.5
renal impairment 4.5
folate deficiency 4.4
pathological fracture 4.4
hypovitaminosis 4.4
rickets 4.4
erythema nodosum 4.4
inflammatory bowel disease 4.3
neurogenic bladder 4.3
sensory neuropathy 4.3
more...
Symptom
vaginal itching 10.0
phosphatemia 9.9
renal colic 8.2
vestibulitis 8.1
frequent urination 7.7
dysuria 6.4
flank pain 5.6
intestinal bleeding 5.4
enuresis 5.4
oliguria 5.2
polyuria 5.1
urinary frequency 5.0
dental pain 4.9
colic 4.5
epigastric pain 4.3
hip pain 4.3
polydipsia 4.0
Wind 3.7
diarrhea 3.7
acute abdomen 3.5
abdominal pain 3.5
agitation 3.1
overweight 3.0
acidity 2.8
hypotonia 2.6
myalgia 2.4
arthralgia 2.3
nausea and vomiting 1.9
constipation 1.8
sleepiness 1.4
exhaustion 1.4
anorexia 1.3
vomiting 1.1
weakness 0.9
angina 0.7
pain 0.7
dyspnea 0.3
analgesia 0.3
collapse 0.3
Drug
Glafenine 11.5
Potassium citrate 11.0
Calcium citrate 10.5
Stiripentol 9.3
Profenid 9.1
Pyridoxamine 8.9
Vitamin B 8.3
Ammonium chloride 7.2
Orlistat 6.5
pyridoxal phosphate 6.4
Clofibrate 6.0
Tocopherol 5.7
Carotenoid 5.6
DMSA 5.5
Nephron 5.4
Rosiglitazone 5.4
Xanthium 5.4
Bifidobacterium 5.2
Nephron 4.9
vitamin E 4.8
ascorbate 4.5
Vitamin E 4.4
citric acid 4.4
Tacrolimus 4.4
PTH 4.4
Diurnal 4.3
G418 4.0
Alanine 3.6
Dial 3.4
Fluorescein 3.2
ROS 3.2
Angiotensin II 2.8
Glutathione 2.7
Indomethacin 2.5
NADH 1.7
Asn 1.6
ampicillin 1.1
Monit -0.0
lysine -0.8
Dermatol -2.9
Enzyme
oxalyl-CoA decarboxylase 13.0
formyl-CoA transferase 12.4
glyoxylate reductase 11.6
glyoxylate reductase 11.6
glycolate dehydrogenase 11.3
oxalate decarboxylase 10.9
hydroxypyruvate reductase 10.2
2-oxoglutarate decarboxylase 10.2
hydroxypyruvate reductase 10.1
AGT 10.0
glycolate oxidase 9.4
BBE 9.3
oxalate oxidase 9.2
ketohexokinase 8.4
kynurenine aminotransferase 7.7
HK2 7.0
MsrA 6.7
transketolase 5.8
PAT 5.4
aldolase 5.3
acyl-CoA oxidase 5.2
urease 5.1
urease 5.0
NADPH oxidase 5.0
alpha-ketoglutarate dehydrogenase 4.8
NADPH oxidase 4.8
lactate dehydrogenase 4.7
xanthine oxidase 4.4
DCF 4.2
gamma-glutamyl transpeptidase 3.9
glucose-6-phosphate dehydrogenase 3.7
alkaline phosphatase 3.7
succinate dehydrogenase 3.7
glucose-6-phosphatase 3.5
catalase 3.5
isocitrate dehydrogenase 3.5
isocitrate dehydrogenase 3.3
superoxide dismutase 3.2
beta-glucuronidase 3.2
NADPH-diaphorase 3.2
proteinase K 3.1
cathepsin D 3.1
CAD 3.0
glutathione peroxidase 3.0
CAD 3.0
citrate synthase 3.0
CAD 2.9
malate dehydrogenase 2.9
glutathione reductase 2.9
phospholipase A2 2.9
dihydrofolate reductase 2.6
acid phosphatase 2.4
carbonic anhydrase 2.2
pepsin 2.0
complex I 2.0
alanine aminotransferase 2.0
renin 2.0
elastase 1.9
ACE 1.9
phospholipase C 1.9
urokinase-type plasminogen activator 1.7
protein kinase C 1.5
beta-galactosidase 1.3
NO synthase 1.1
APC 1.1
peroxidase 1.1
DNA polymerase 1.0
calcineurin 1.0
creatine kinase 0.9
protein kinase 0.8
aspartate aminotransferase 0.7
glutathione S-transferase 0.6
reverse transcriptase 0.1
ATPase 0.1
caspase-3 -0.0
mitogen-activated protein kinase -1.5
Compound
Maltisorb 14.1
2,3,4-trihydroxybutanoic acid 12.3
Isocarboxazide 11.9
oxalate 11.2
Isocarboxazide 11.2
Succinimide 11.2
Hydroxypyruvate 10.6
Ethoxzolamide 10.2
POPOP 10.2
oxalic acid 10.0
Pyridoxine 9.9
Glycolate 9.8
PH2 9.7
Glyoxylate 9.3
Triamterene 9.3
Bergenin 9.2
Hexachlorobutadiene 9.2
oxalic acid 9.2
oxalic acid 9.2
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
oxalic acid 9.1
Ricinoleic acid 9.1
threonate 9.1
Trisodium phosphate 8.9
Pyridoxamine 8.9
butoxyacetic acid 8.8
D 3 8.6
Tamsulosin 8.1
Lupeol 7.8
1,3-butanediol 7.7
1,3-butanediol 7.6
DGE 7.4
Aspartame 7.4
DGE 7.4
DGE 7.4
Cystine 7.4
Uric acid 7.2
Deoxycholic acid 7.0
Calcium carbonate 6.9
Apocynin 6.9
Loperamide 6.8
Melamine 6.8
Cystine 6.7
glutaryl-CoA 6.7
HPT 6.7
PEG 6.5
Xylitol 6.4
4-hydroxyproline 6.3
4-hydroxyproline 6.3
4-hydroxyproline 6.3
4-hydroxyproline 6.3
4-hydroxyproline 6.3
4-hydroxyproline 6.3
Fucoidan 6.3
Lip 6.2
HPP 6.2
Ketoprofen 6.1
PEG 6.1
Hydroxyproline 6.0
PGJ2 5.9
Clofibrate 5.9
calcium 5.8
alpha-ketoisocaproate 5.7
Spironolactone 5.6
Losartan 5.6
Sorbitol 5.5
creatinine 5.5
PAT 5.5
DIDS 5.5
Formate 5.4
HCA 5.4
malonic acid 5.4
Acetazolamide 5.4
Enalapril 5.3
Octreotide 5.1
hippurate 5.1
Eosin 5.1
adipate 5.0
Atorvastatin 4.9
25-dihydroxycholecalciferol 4.9
octanoic acid 4.9
ASC 4.9
Linoleic acid 4.9
Eosin 4.8
POP 4.8
Lactic acid 4.7
CIT 4.7
Lactate 4.7
CIT 4.6
Oleic acid 4.6
2-oxoglutarate 4.6
DPA 4.5
DPA 4.5
DPA 4.5
DPA 4.5
DPA 4.5
AHA 4.5
8-OHdG 4.4
PLP 4.4
phosphate 4.4
Ang II 4.3
Carbachol 4.3
CCC 4.2
Pyruvate 4.2
ammonium 4.2
vitamin D 4.1
potassium 4.1
Vitamin E 4.1
N-acetylcysteine 4.0
CAT 4.0
CAT 4.0
Taurine 3.9
UTP 3.9
Sodium 3.9
GAL 3.9
CAT 3.9
Parenteral 3.8
phosphorus 3.8
Arachidonic acid 3.8
Hematoxylin 3.7
Alanine 3.7
proline 3.7
TTP 3.7
4-chlorophenyl 3.6
4-chlorophenyl 3.6
urea 3.6
Ascorbic acid 3.6
carbonate 3.6
nicotinic acid 3.5
nicotinic acid 3.5
nicotinic acid 3.5
Quercetin 3.5
nicotinamide 3.4
Vitamin D 3.4
Serine 3.4
Rapamycin 3.4
succinic acid 3.3
sodium 3.3
Dial 3.3
Verapamil 3.3
MgO 3.3
propylene glycol 3.2
PDB 3.2
alanine 3.2
Verapamil 3.2
salt 3.2
dUTP 3.2
propylene glycol 3.1
more...