Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020473 (hyperlipidemia)
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Human Gene/Protein
acetyl-Coenzyme A acetyltransferase 2 11.0
FLJ20584 11.0
ATP synthase mitochondrial F1 complex assembly factor 1 11.0
neutrophil cytosol factor 2 10.0
carboxylesterase 1A1 10.0
serologically defined colon cancer antigen 3 10.0
LSR protein 9.6
Crumbs homolog 2 9.4
Apolipoprotein A-I binding protein 9.4
Transmembrane protein 98 9.4
aminocarboxymuconate semialdehyde decarboxylase 9.4
ABCG8 protein 9.4
HSP90BB 9.4
CD81 antigen 9.4
Upstream transcription factor 1 9.4
ALSS 9.4
LMNA protein 9.0
C12orf49 9.0
hydroxysteroid (17-beta) dehydrogenase 4 9.0
UXS1 8.6
PRKWNK4 8.6
ACOT9 8.6
mitochondrial solute carrier protein 8.6
sPLA(2)-IIE 8.6
PBX4 8.5
1-acylglycerol-3-phosphate O-acyltransferase 2 8.5
apolipoprotein B48 receptor 8.4
ANGPTL3 protein 8.4
GAPT 8.4
SET and MYND domain containing 3 8.4
SLC25A40 8.4
OSBPL10 8.4
5-hydroxytryptamine (serotonin) receptor 2C 8.2
HSPA12A 8.2
Apolipoprotein O 8.2
LDLB 8.2
CREB3L3 8.2
HTGL 8.0
carnitine O-octanoyltransferase 8.0
OSBPL9 8.0
C12orf51 8.0
Low-density lipoprotein receptor-related protein 6 7.9
EH domain-binding protein 1 7.8
ORP10 7.8
Apolipoprotein E3 7.8
nbr 7.8
LPGAT1 7.8
protein tyrosine phosphatase mu 7.8
apolipoprotein A-V 7.8
Angiopoietin-like 3 7.8
HLP 7.7
ATP-binding cassette transporter-1 7.7
ADCK4 7.7
HSFA 7.6
CILP2 7.6
COPS8 7.6
HC9 7.6
G0S2 protein 7.6
peroxisomal biogenesis factor 7.6
ZFP161 7.6
CHOD 7.6
ACAT1 protein 7.5
MYO1F 7.5
OSBPL2 7.5
anion transporter 1 7.5
HCCR-1 7.5
Aquaporin-7 7.5
Lipolysis-stimulated lipoprotein receptor 7.4
hepatic lipase 7.4
inosine monophosphate dehydrogenase 2 7.4
HCLS1-associated protein X-1 7.4
sterol regulatory element binding protein-2 7.4
apolipoprotein E3 7.3
GATAD2B 7.3
SEIPIN 7.3
AKAP10 7.3
Niemann-Pick C1-like 1 7.3
apolipoprotein CII 7.2
Microsomal triglyceride transfer protein 7.2
GPIHBP1 7.2
more...
Disease
hyperlipidemia 11.0
Chronic adhesive pericarditis 11.0
HMSNO 11.0
filiform wart 11.0
Xanthoma tuberosum 11.0
Combined hyperlipidemia 10.7
Secondary hyperlipidemia 10.6
Lipemia retinalis 10.5
Type IIb hyperlipidemia 10.0
Pure hypercholesterolemia 10.0
Subclavian Steal 10.0
Severe toxemia 10.0
virus related cancer 10.0
Progressing stroke 10.0
Familial combined hyperlipidemia 9.8
Eruptive xanthomas 9.7
Zieve's syndrome 9.6
Fat redistribution 9.4
Focal vasculitis 9.4
Gallbladder mucocele 9.4
Postoperative pulmonary edema 9.4
Type V hyperlipidemia 9.4
sensory nerve disorder 9.4
Postmenopausal symptoms 9.4
Recurrent proteinuria 9.4
familial hypertriglyceridemia 9.4
familial hyperlipidemia 9.3
FHBL2 9.2
Type V hyperlipoproteinemia 9.1
endometrial dysplasia 9.0
Primary hypercholesterolemia 9.0
Necrobiotic xanthogranuloma with paraproteinemia 9.0
Reclus 9.0
Type III hyperlipoproteinemia 8.9
lipoprotein disorder 8.9
hyperchylomicronemia 8.7
Tendon xanthoma 8.6
Hydrallantois 8.6
Alimentary obesity 8.6
Xanthelasma palpebrarum 8.6
Achilles tendon thickening 8.6
Idiopathic acute pancreatitis 8.6
Migratory polyarthritis 8.6
Chronic pericarditis 8.4
hyperheparinemia 8.4
Generalized osteopenia 8.4
Simple obesity 8.4
Cellular blue nevus 8.4
Ischemic cerebral infarction 8.2
Gastric xanthelasma 8.2
Retinal artery occlusion 8.1
Cheiro-oral syndrome 8.0
hypoalphalipoproteinemia 7.9
xanthomatosis 7.9
GSD IX 7.9
hyperlipoproteinemia 7.9
GSD I 7.8
lipid disorder 7.8
metabolic syndrome X 7.8
Acquired generalized lipodystrophy 7.8
Pseudocholinesterase deficiency 7.8
hypolipoproteinemia 7.7
Endocrine pancreas 7.6
Non-Q wave myocardial infarction 7.6
Endocrine pancreas 7.6
lipoproteinemia 7.6
xanthoma 7.6
HLP 7.6
cholesterol ester storage disease 7.5
Branch retinal vein occlusion 7.5
Diabetic macroangiopathy 7.5
Infected pancreatic necrosis 7.5
cigarette abuse 7.5
arcus senilis 7.5
Familial defective apolipoprotein B-100 7.4
Atherosclerotic occlusive disease 7.4
Xanthoma disseminatum 7.4
Subcortical vascular dementia 7.4
Mitochondrial neurogastrointestinal encephalopathy 7.4
Alstrom syndrome 7.3
more...
Symptom
Homan's sign 8.4
cardiovascular disability 8.2
jaundice of the skin 7.0
Upper abdominal pain 6.6
unable to sleep 6.4
hypoproteinemia 6.1
Cushingoid 6.0
Sudden deafness 5.8
Cushingoid 5.7
chyluria 5.7
musculoskeletal impairment 5.6
Acute chest pain 5.4
Amaurosis fugax 5.3
exertional chest pain 5.2
ketonuria 5.0
facial droop 5.0
hepatomegaly 4.9
intestinal angina 4.9
corpulence 4.7
adipsia 4.4
overweight 4.4
generalized abdominal pain 4.4
angina 4.3
pedal edema 4.2
No adverse effect 4.2
cardiovascular impairment 4.2
glossodynia 4.2
Visual disturbances 4.1
polymyalgia 4.1
Macula 4.1
astasia 4.0
hepatosplenomegaly 4.0
arm pain 4.0
lightheadedness 4.0
Signs and Symptoms 3.8
nocturnal polyuria 3.8
exertional angina 3.7
emaciation 3.7
autodigestion 3.7
atypical chest pain 3.6
frequent urination 3.6
livedo 3.5
scaly skin 3.5
Poor sleep 3.5
polydipsia 3.4
chronic back pain 3.4
eye pain 3.4
rectal pain 3.4
giddiness 3.3
giddiness 3.3
polyuria 3.3
menopausal symptoms 3.3
rales 3.2
leg edema 3.2
muscle cramps 3.1
myalgia 3.1
chest pain 3.1
orthopnea 3.1
ACHE 3.1
heel pain 3.1
dysarthria 3.0
chest tightness 3.0
snoring 2.9
Decreased activity 2.9
clumsiness 2.9
rigors 2.9
dark urine 2.8
vertigo 2.8
bedwetting 2.8
night sweats 2.7
neck stiffness 2.7
constipation 2.7
cachexia 2.7
flushing 2.6
thirsty 2.6
asthenia 2.6
Physical findings 2.6
bloating 2.6
right upper quadrant pain 2.6
numbness 2.5
more...
Drug
Ibrolipim 11.0
Xenalipin 11.0
Monatepil maleate 10.0
Clinofibrate 10.0
Dioscorea rhizome 9.6
Asperlin 9.4
Choloxin 9.0
Furazabol 9.0
Colestimide 9.0
Schisandra fruit 8.6
Colesevelam 8.6
Halofenate 8.4
Colestid 8.4
Propylene glycol alginate 8.4
Lexiva 8.4
Lifibrol 8.3
Gemfibrozil 8.0
Cerivastatin sodium 8.0
Geodon 7.8
Bezafibrate 7.8
Niceritrol 7.7
Duolip 7.7
Aquavan 7.6
Torisel 7.6
Mepartricin 7.5
Geodon 7.5
Ciprofibrate 7.5
Lescol 7.4
Avasimibe 7.4
Muromonab-CD3 7.4
Psyllium husk 7.4
Fosamprenavir calcium 7.3
Lescol 7.2
Longgu 7.2
Tesaglitazar 7.1
Fangfeng 7.1
Carnauba wax 7.1
Omacor 7.1
Rosuvastatin calcium 7.0
Cellcept 7.0
Cellcept 7.0
Tazorac 7.0
Colestipol 6.9
Compazine 6.9
Muraglitazar 6.9
Rosuvastatin 6.8
Simvastatin 6.8
Agenerase 6.8
Ezetimibe 6.7
Fosamprenavir 6.7
Myo-Inositol 6.6
Ziprasidone hydrochloride 6.6
Pravastatin 6.5
Micardis 6.5
Magnolia bark 6.4
Suloctidil 6.4
Compazine 6.4
Estulic 6.4
Bexarotene 6.3
Cinnamon bark 6.3
CS-514 6.3
Poloxamer 6.3
Cardura 6.3
Hakka 6.3
Tora 6.2
Berberine chloride 6.2
Red ginseng 6.1
Tham 6.1
Zithromax 6.0
Clofibrate 6.0
NAH 6.0
Imagent 6.0
Peanut oil 5.9
Lovastatin 5.8
Questran 5.8
Pyridoxamine 5.8
Lipitor 5.8
Lipitor 5.8
Torcetrapib 5.8
Vitamin-E 5.7
more...
Enzyme
carnitine O-octanoyltransferase 7.6
citryl-CoA lyase 7.5
lipoprotein lipase 7.0
CYP7A1 6.9
indole 2,3-dioxygenase 6.6
creatinine iminohydrolase 6.6
3-hydroxy-3-methylglutaryl coenzyme A reductase 6.6
EC 1.1.1.38 6.5
LPL 6.2
cholesterol acyltransferase 6.0
ACAT 5.9
rhamnulose-1-phosphate aldolase 5.9
3-hydroxy-3-methylglutaryl-CoA reductase 5.8
leucine aminotransferase 5.8
lecithin:cholesterol acyltransferase 5.8
aminocarboxymuconate-semialdehyde decarboxylase 5.7
proprotein convertase 5.5
CYP27A1 5.5
acetyl-CoA carboxylase 5.3
monoacylglycerol acyltransferase 5.3
RPH 5.3
fatty-acid synthase 5.3
acyl-CoA oxidase 5.1
glucose-6-phosphatase 5.1
diacylglycerol acyltransferase 5.1
GP-I 5.1
3-hydroxyanthranilic acid oxygenase 5.0
calpain 10 5.0
amylomaltase 4.9
malonyl-CoA decarboxylase 4.8
dimethylarginine dimethylaminohydrolase 4.7
E-2 4.7
cholesterol esterase 4.7
citrate cleavage enzyme 4.6
hormone-sensitive lipase 4.6
lipase 4.6
bile salt hydrolase 4.6
AST 4.6
AMPK 4.5
AMP-activated protein kinase 4.5
glycerol kinase 4.4
nicotinamide N-methyltransferase 4.4
paraoxonase 4.4
palmitoyl-CoA hydrolase 4.4
glycerol-3-phosphate oxidase 4.3
EC 1.1.1.40 4.3
ketohexokinase 4.3
2,4-dienoyl-CoA reductase 4.3
alanine aminotransferase 4.1
sterol carrier protein 4.1
cholesterol oxidase 4.1
aspartate aminotransferase 4.1
DSR 4.1
carnosinase 4.0
nicotinamide phosphoribosyltransferase 4.0
CPT 4.0
SOR 4.0
11beta-hydroxysteroid dehydrogenase 4.0
PWD 3.9
farnesyltransferase 3.9
citrate lyase 3.8
paraoxonase 3.8
biliverdin reductase 3.8
CAD 3.8
hepsin 3.8
hepsin 3.8
CAD 3.8
CAD 3.7
glycerophosphate acyltransferase 3.7
asparaginase 3.7
glycine N-methyltransferase 3.7
oxoglutarate dehydrogenase 3.6
lecithin:retinol acyltransferase 3.6
AMPK 3.6
kynurenine aminotransferase 3.5
ACE 3.5
lysine acetyltransferase 3.5
creatine kinase 3.4
squalene epoxidase 3.4
furin 3.4
more...
Compound
Acroptilin 11.0
Asperlin 9.4
C8H12O4 9.4
Prunin 9.0
Eburicoic acid 9.0
8,9-DiHETrE 8.8
1-phenyl-2-propen-1-one 8.8
1,2,3-butanetriol 8.6
Mahanimbine 8.6
Soriatane 8.6
Vitamin U 8.4
Triton WR-1339 8.3
Gardenin 8.2
2,3,4-trihydroxybutanoic acid 8.2
Eriocitrin 8.2
5-fluoro-1H-indole 8.2
methyl dihydrogen phosphate 8.2
Guggulsterone 8.0
ML 1024 7.8
4-methyl-1,3-thiazole 7.8
Alstonine 7.6
Fenofibrate 7.6
Ebelactone B 7.5
Pantethine 7.4
Dicentrine 7.4
2,4,6-octatrienoic acid 7.4
Tiadenol 7.4
Loganic acid 7.4
Atorvastatin 7.2
Compazine 7.1
Gelsemine 7.0
Swertiamarin 7.0
5,6-DHET 7.0
1'-Acetoxychavicol acetate 7.0
Colestipol 6.9
Probucol 6.9
AHCT 6.9
Rhaponticin 6.9
Pravastatin 6.8
NAMS 6.7
Taurodeoxycholic acid 6.7
Fluvastatin 6.7
Campesterol 6.7
Lovastatin 6.6
glutaryl-CoA 6.5
dimethyl malate 6.4
Cuminaldehyde 6.4
Vindoline 6.4
PTMS 6.4
Ronicol 6.4
Isoorientin 6.4
Cholesteryl oleate 6.4
Cynaropicrin 6.4
DHA ethyl ester 6.4
Statin 6.4
Cholesteryl oleate 6.3
Tetrahydrocurcumin 6.3
C10H16 6.3
Jatrorrhizine 6.2
M 14 6.2
CPIB 6.2
Glycochenodeoxycholic acid 6.2
Biguanide 6.2
Cerivastatin 6.1
Clofibrate 6.1
Oleoyl-CoA 6.1
Glimepiride 6.1
Berberine chloride 6.1
Cynaropicrin 6.1
nicotinic acid 6.1
HMG-CoA 6.1
nicotinic acid 6.0
nicotinic acid 6.0
Gentiopicroside 6.0
Terazosin 6.0
Glycitein 6.0
Moxonidine 6.0
Tectorigenin 6.0
Monoolein 5.9
Salvianolic acid A 5.9
more...