Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020473 (
hyperlipidemia
)
15,891
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
insulin
2556
HDL
1216
Sep
979
lipoprotein lipase
452
Mol
396
apolipoprotein
361
LDL receptor
337
apolipoprotein B
325
HMG-CoA reductase
289
apoE
268
albumin
238
reductase
233
hemoglobin
227
leptin
223
apolipoprotein E
197
fibrinogen
189
peroxisome proliferator-activated receptor
184
C-reactive protein
183
superoxide dismutase
183
tumor necrosis factor
173
gut
172
adiponectin
171
She
159
Lp(a)
140
hepatic lipase
134
TNF
133
cytokine
132
lipase
132
collagen
126
A-I
125
chronic renal failure
119
glucagon
118
catalase
118
aspartate aminotransferase
117
alanine aminotransferase
111
GSH
109
endoplasmic reticulum
109
ATP
103
glutathione peroxidase
101
renin
100
IL-6
94
fatty acid synthase
94
serum albumin
90
AMP-activated protein kinase
88
apoB-100
86
low-density lipoprotein receptor
86
peroxisome proliferator-activated receptor gamma
86
PPAR
84
HDL2
80
calcineurin
79
mTOR
79
interleukin-6
79
alkaline phosphatase
77
epididymal
76
AST
73
AMPK
72
Pol
71
proprotein convertase subtilisin/kexin type 9
71
cholesteryl ester transfer protein
70
MRI
68
plasminogen activator inhibitor-1
67
creatine kinase
66
amylase
65
ACE
64
growth hormone
64
thrombin
63
CYP7A1
62
angiotensin II
62
protease inhibitor
61
lactate dehydrogenase
61
SOD
59
cytochrome P450
57
lipopolysaccharide
56
LDLR
56
CD36
55
apolipoprotein A-I
54
acetyl-CoA carboxylase
53
vascular endothelium
53
glucose-6-phosphatase
53
LPL
51
more...
Disease
hyperlipidemia
15891
diabetes
4598
hypertension
4271
obesity
2714
atherosclerosis
2576
cardiovascular disease
1398
hyperglycemia
1196
hypercholesterolemia
1169
type 2 diabetes
1040
coronary artery disease
963
metabolic syndrome
831
stroke
764
coronary heart disease
753
dyslipidemia
677
myocardial infarction
610
fatty liver
545
cancer
532
renal disease
531
proteinuria
424
hyperinsulinemia
422
glucose intolerance
404
myocardial ischemia
345
nephrotic syndrome
341
plaque
302
heart failure
294
vascular disease
280
HIV
229
pancreatitis
219
ischemia
218
renal failure
211
depression
206
heart disease
205
hyperlipoproteinemia
195
osteoporosis
189
tumor
181
arteriosclerosis
179
cirrhosis
176
anemia
176
hyperuricemia
172
glomerulosclerosis
170
chronic renal failure
168
acute pancreatitis
166
liver disease
164
hypothyroidism
161
acute myocardial infarction
161
diabetic nephropathy
149
lipodystrophy
136
hypoglycemia
135
dementia
131
Nonalcoholic fatty liver
125
Alzheimer's disease
123
hepatocellular carcinoma
121
congestive heart failure
120
essential hypertension
111
GSH
109
systemic lupus erythematosus
106
type 1 diabetes
99
alcoholic fatty liver
97
AIDS
96
ventricular hypertrophy
96
myopathy
94
metabolic disorder
93
peripheral vascular disease
93
xanthoma
92
lipid disorder
91
atherosclerotic cardiovascular disease
90
gallstones
89
chronic obstructive pulmonary disease
87
immunodeficiency
86
renal insufficiency
85
retinopathy
84
gout
83
erectile dysfunction
83
cardiomyopathy
82
cognitive impairment
82
hyperhomocysteinemia
81
abdominal obesity
80
HDL2
80
malnutrition
77
SEM
73
more...
Symptom
overweight
281
angina
207
pain
153
hepatomegaly
88
abdominal pain
76
chest pain
76
fatigue
72
headache
69
weakness
68
diarrhea
63
vomiting
48
nausea
41
hypoproteinemia
38
anesthesia
37
hepatosplenomegaly
35
dyspnea
34
seizures
34
constipation
33
myalgia
29
vertigo
25
anorexia
25
flushing
20
dizziness
19
cough
19
cachexia
18
starvation
17
polyuria
15
dysarthria
15
discomfort
15
splenomegaly
15
shortness of breath
15
numbness
15
discomfort
14
respiratory distress
14
ataxia
14
collapse
14
insomnia
14
sleepiness
14
syncope
13
spasm
13
tremor
13
back pain
13
thinning
12
polydipsia
12
snoring
11
arthralgia
11
ketonuria
9
memory loss
9
hunger
8
erythema
8
menopausal symptoms
8
hypothermia
8
tinnitus
8
asthenia
8
nausea and vomiting
8
exertional dyspnea
8
hemiplegia
8
emaciation
7
lethargy
7
epigastric pain
7
Cushingoid
7
regurgitation
7
dysuria
6
cerebellar ataxia
6
shoulder pain
6
cyanosis
6
Ill
6
Cushingoid
6
paresis
5
leg pain
5
exertional angina
5
chyluria
5
oliguria
5
bloating
5
apathy
5
livedo
5
functional recovery
5
paresthesia
4
pallor
4
abdominal discomfort
4
more...
Drug
Cardiovasc
336
niacin
98
Simvastatin
95
vitamin E
90
Dermatol
79
Nephron
56
Nephron
51
Dial
50
Gemfibrozil
43
Monit
42
Pravastatin
37
ascorbate
37
Lovastatin
37
ROS
34
Bezafibrate
30
lysine
28
Vitamin E
27
Rosuvastatin
26
Ezetimibe
24
Ethanol
22
caffeine
22
Tacrolimus
22
Fructose
21
nitroglycerin
21
EPA
19
Clofibrate
18
Glucagon
18
Albumin
17
Adriamycin
16
Vitamin A
15
Kenyan
13
Propofol
12
Neoral
12
MAP
11
Bifidobacterium
11
PTH
10
CTX
10
Colesevelam
10
Estrogens
10
ADM
10
IL-2
9
ROC
9
EE2
9
Angiotensin II
9
Isotretinoin
8
Asn
8
ABC
8
Orlistat
8
Leaf
8
Poloxamer
8
Rosiglitazone
8
ATV
7
Ciprofibrate
7
Retinoic acid
7
Everolimus
7
Bexarotene
7
Growth hormone
6
Histamine
6
Olive oil
6
Spectrum
6
Ginseng
6
Prednisolone
6
ENT
6
Troglitazone
6
Perindopril
6
NADH
6
citric acid
6
Rutin
5
Aloe
5
ALA
5
Growth hormone
5
CSF
5
Parkin
5
Parkin
5
Lipidex
5
CTX
5
Heme
5
CTA
5
CTX
5
Colestimide
4
more...
Enzyme
lipoprotein lipase
454
superoxide dismutase
240
alanine aminotransferase
234
lipase
228
aspartate aminotransferase
188
AMP-activated protein kinase
148
catalase
139
ACE
103
glutathione peroxidase
101
creatine kinase
101
renin
100
protein kinase
99
mitogen-activated protein kinase
94
calcineurin
81
alkaline phosphatase
78
AMPK
76
AST
73
AMPK
72
3-hydroxy-3-methylglutaryl coenzyme A reductase
69
cholesterol acyltransferase
65
lactate dehydrogenase
65
thrombin
64
acetyl-CoA carboxylase
58
CYP7A1
58
tissue plasminogen activator
54
glucose-6-phosphatase
53
LPL
51
ERK
51
peroxidase
46
gamma-glutamyl transpeptidase
39
reverse transcriptase
38
protein kinase C
38
CPT
37
lecithin:cholesterol acyltransferase
33
3-hydroxy-3-methylglutaryl-CoA reductase
32
NADPH oxidase
32
caspase-3
30
CAD
30
CAD
30
CAD
30
NO synthase
28
glucose-6-phosphate dehydrogenase
28
luciferase
28
focal adhesion kinase
28
APC
27
hormone-sensitive lipase
27
NADPH oxidase
26
proprotein convertase
25
ATPase
25
acetylcholinesterase
25
subtilisin
23
thromboplastin
23
xanthine oxidase
23
cholinesterase
23
alpha-glucosidase
21
phosphoenolpyruvate carboxykinase
21
phosphodiesterase
21
phospholipase A2
19
ACS
18
paraoxonase
18
asparaginase
17
CYP3A4
17
acyl-CoA oxidase
17
furin
17
glutathione reductase
16
diacylglycerol acyltransferase
15
paraoxonase
15
phosphoenolpyruvate carboxykinase
14
glucokinase
14
phosphoenolpyruvate carboxykinase
14
proteasome
14
glutathione S-transferase
13
CPT
13
MEK
12
aldehyde dehydrogenase
12
GSK
12
CYP27A1
12
CPT
12
cholesterol esterase
12
alcohol dehydrogenase
12
more...
Compound
glucose
2113
Clin
1534
Dec
1151
Cardiol
486
water
366
creatinine
354
calcium
351
oxygen
309
DNA
264
Cholesterol
250
sodium
234
nitric oxide
213
Insulin
212
ethanol
189
acetate
153
urea
139
TNF
133
nicotinic acid
119
phosphate
113
GSH
110
GSH
110
salt
109
homocysteine
106
arginine
106
nitrogen
106
nicotinic acid
105
ATP
103
glycerol
101
nicotinic acid
99
nicotinic acid
99
CoA
95
sulfate
95
His
91
Atorvastatin
81
potassium
81
iron
73
palmitic acid
73
Triton
71
galactose
63
alloxan
61
Triton WR-1339
61
Fenofibrate
58
palmitic acid
56
methionine
55
Statin
53
ADP
53
Dial
51
MDA
51
STZ
50
vitamin D
50
Estrogen
49
copper
49
HMG-CoA
48
hydrogen
48
FFA
47
Cyclosporine
46
CO2
44
cysteine
43
Rapamycin
43
ADP
41
aldosterone
40
ADP
40
zinc
39
tyrosine
39
retinol
38
cAMP
37
prostacyclin
36
PMA
36
lysine
35
leucine
35
Lovastatin
34
Metformin
33
Metformin
33
Vitamin E
32
Pravastatin
32
ASA
32
methanol
32
TSH
31
alanine
31
AMP
31
more...