Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020473 (hyperlipidemia)
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Human Gene/Protein
FLJ20584 11.0
acetyl-Coenzyme A acetyltransferase 2 11.0
ATP synthase mitochondrial F1 complex assembly factor 1 11.0
carboxylesterase 1A1 10.0
serologically defined colon cancer antigen 3 10.0
neutrophil cytosol factor 2 10.0
LSR protein 9.6
Crumbs homolog 2 9.4
ALSS 9.4
ABCG8 protein 9.4
aminocarboxymuconate semialdehyde decarboxylase 9.4
Apolipoprotein A-I binding protein 9.4
HSP90BB 9.4
Transmembrane protein 98 9.4
CD81 antigen 9.4
Upstream transcription factor 1 9.4
C12orf49 9.0
hydroxysteroid (17-beta) dehydrogenase 4 9.0
LMNA protein 9.0
UXS1 8.6
ACOT9 8.6
mitochondrial solute carrier protein 8.6
sPLA(2)-IIE 8.6
PRKWNK4 8.6
1-acylglycerol-3-phosphate O-acyltransferase 2 8.5
PBX4 8.5
SET and MYND domain containing 3 8.4
ANGPTL3 protein 8.4
GAPT 8.4
apolipoprotein B48 receptor 8.4
OSBPL10 8.4
SLC25A40 8.4
Apolipoprotein O 8.2
CREB3L3 8.2
5-hydroxytryptamine (serotonin) receptor 2C 8.2
HSPA12A 8.2
LDLB 8.2
HTGL 8.0
carnitine O-octanoyltransferase 8.0
C12orf51 8.0
more...
Disease
Xanthoma tuberosum 11.0
Chronic adhesive pericarditis 11.0
hyperlipidemia 11.0
HMSNO 11.0
filiform wart 11.0
Combined hyperlipidemia 10.7
Secondary hyperlipidemia 10.6
Lipemia retinalis 10.5
Pure hypercholesterolemia 10.0
Progressing stroke 10.0
virus related cancer 10.0
Subclavian Steal 10.0
Type IIb hyperlipidemia 10.0
Severe toxemia 10.0
Familial combined hyperlipidemia 9.8
Eruptive xanthomas 9.7
Zieve's syndrome 9.6
sensory nerve disorder 9.4
Fat redistribution 9.4
Postmenopausal symptoms 9.4
Focal vasculitis 9.4
Gallbladder mucocele 9.4
Recurrent proteinuria 9.4
Postoperative pulmonary edema 9.4
Type V hyperlipidemia 9.4
familial hypertriglyceridemia 9.4
familial hyperlipidemia 9.3
FHBL2 9.2
Type V hyperlipoproteinemia 9.1
Necrobiotic xanthogranuloma with paraproteinemia 9.0
Primary hypercholesterolemia 9.0
Reclus 9.0
endometrial dysplasia 9.0
Type III hyperlipoproteinemia 8.9
lipoprotein disorder 8.9
hyperchylomicronemia 8.7
Alimentary obesity 8.6
Hydrallantois 8.6
Tendon xanthoma 8.6
Idiopathic acute pancreatitis 8.6
more...
Symptom
Homan's sign 8.4
cardiovascular disability 8.2
jaundice of the skin 7.0
Upper abdominal pain 6.6
unable to sleep 6.4
hypoproteinemia 6.1
Cushingoid 6.0
Sudden deafness 5.8
Cushingoid 5.7
chyluria 5.7
musculoskeletal impairment 5.6
Acute chest pain 5.4
Amaurosis fugax 5.3
exertional chest pain 5.2
ketonuria 5.0
facial droop 5.0
hepatomegaly 4.9
intestinal angina 4.9
corpulence 4.7
adipsia 4.4
overweight 4.4
generalized abdominal pain 4.4
angina 4.3
pedal edema 4.2
No adverse effect 4.2
cardiovascular impairment 4.2
glossodynia 4.2
Visual disturbances 4.1
polymyalgia 4.1
Macula 4.1
astasia 4.0
hepatosplenomegaly 4.0
arm pain 4.0
lightheadedness 4.0
Signs and Symptoms 3.8
nocturnal polyuria 3.8
exertional angina 3.7
emaciation 3.7
autodigestion 3.7
atypical chest pain 3.6
more...
Drug
Ibrolipim 11.0
Xenalipin 11.0
Clinofibrate 10.0
Monatepil maleate 10.0
Dioscorea rhizome 9.6
Asperlin 9.4
Colestimide 9.0
Choloxin 9.0
Furazabol 9.0
Schisandra fruit 8.6
Colesevelam 8.6
Lexiva 8.4
Colestid 8.4
Halofenate 8.4
Propylene glycol alginate 8.4
Lifibrol 8.3
Gemfibrozil 8.0
Cerivastatin sodium 8.0
Geodon 7.8
Bezafibrate 7.8
Duolip 7.7
Niceritrol 7.7
Aquavan 7.6
Torisel 7.6
Geodon 7.5
Mepartricin 7.5
Ciprofibrate 7.5
Lescol 7.4
Avasimibe 7.4
Psyllium husk 7.4
Muromonab-CD3 7.4
Fosamprenavir calcium 7.3
Lescol 7.2
Longgu 7.2
Tesaglitazar 7.1
Fangfeng 7.1
Carnauba wax 7.1
Omacor 7.1
Rosuvastatin calcium 7.0
Cellcept 7.0
more...
Enzyme
carnitine O-octanoyltransferase 7.6
citryl-CoA lyase 7.5
lipoprotein lipase 7.0
CYP7A1 6.9
creatinine iminohydrolase 6.6
indole 2,3-dioxygenase 6.6
3-hydroxy-3-methylglutaryl coenzyme A reductase 6.6
EC 1.1.1.38 6.5
LPL 6.2
cholesterol acyltransferase 6.0
ACAT 5.9
rhamnulose-1-phosphate aldolase 5.9
3-hydroxy-3-methylglutaryl-CoA reductase 5.8
leucine aminotransferase 5.8
lecithin:cholesterol acyltransferase 5.8
aminocarboxymuconate-semialdehyde decarboxylase 5.7
proprotein convertase 5.5
CYP27A1 5.5
acetyl-CoA carboxylase 5.3
monoacylglycerol acyltransferase 5.3
RPH 5.3
fatty-acid synthase 5.3
acyl-CoA oxidase 5.1
glucose-6-phosphatase 5.1
diacylglycerol acyltransferase 5.1
GP-I 5.1
3-hydroxyanthranilic acid oxygenase 5.0
calpain 10 5.0
amylomaltase 4.9
malonyl-CoA decarboxylase 4.8
dimethylarginine dimethylaminohydrolase 4.7
E-2 4.7
cholesterol esterase 4.7
citrate cleavage enzyme 4.6
hormone-sensitive lipase 4.6
lipase 4.6
bile salt hydrolase 4.6
AST 4.6
AMPK 4.5
AMP-activated protein kinase 4.5
more...
Compound
Acroptilin 11.0
Asperlin 9.4
C8H12O4 9.4
Eburicoic acid 9.0
Prunin 9.0
1-phenyl-2-propen-1-one 8.8
8,9-DiHETrE 8.8
Mahanimbine 8.6
Soriatane 8.6
1,2,3-butanetriol 8.6
Vitamin U 8.4
Triton WR-1339 8.3
Eriocitrin 8.2
methyl dihydrogen phosphate 8.2
5-fluoro-1H-indole 8.2
2,3,4-trihydroxybutanoic acid 8.2
Gardenin 8.2
Guggulsterone 8.0
4-methyl-1,3-thiazole 7.8
ML 1024 7.8
Alstonine 7.6
Fenofibrate 7.6
Ebelactone B 7.5
Pantethine 7.4
Loganic acid 7.4
Dicentrine 7.4
Tiadenol 7.4
2,4,6-octatrienoic acid 7.4
Atorvastatin 7.2
Compazine 7.1
Gelsemine 7.0
5,6-DHET 7.0
1'-Acetoxychavicol acetate 7.0
Swertiamarin 7.0
Colestipol 6.9
Probucol 6.9
Rhaponticin 6.9
AHCT 6.9
Pravastatin 6.8
NAMS 6.7
more...