Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020473 (
hyperlipidemia
)
15,891
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
insulin
2556
HDL
1216
Sep
979
lipoprotein lipase
452
Mol
396
apolipoprotein
361
LDL receptor
337
apolipoprotein B
325
HMG-CoA reductase
289
apoE
268
albumin
238
reductase
233
hemoglobin
227
leptin
223
apolipoprotein E
197
fibrinogen
189
peroxisome proliferator-activated receptor
184
C-reactive protein
183
superoxide dismutase
183
tumor necrosis factor
173
gut
172
adiponectin
171
She
159
Lp(a)
140
hepatic lipase
134
TNF
133
lipase
132
cytokine
132
collagen
126
A-I
125
chronic renal failure
119
glucagon
118
catalase
118
aspartate aminotransferase
117
alanine aminotransferase
111
endoplasmic reticulum
109
GSH
109
ATP
103
glutathione peroxidase
101
renin
100
more...
Disease
hyperlipidemia
15891
diabetes
4598
hypertension
4271
obesity
2714
atherosclerosis
2576
cardiovascular disease
1398
hyperglycemia
1196
hypercholesterolemia
1169
type 2 diabetes
1040
coronary artery disease
963
metabolic syndrome
831
stroke
764
coronary heart disease
753
dyslipidemia
677
myocardial infarction
610
fatty liver
545
cancer
532
renal disease
531
proteinuria
424
hyperinsulinemia
422
glucose intolerance
404
myocardial ischemia
345
nephrotic syndrome
341
plaque
302
heart failure
294
vascular disease
280
HIV
229
pancreatitis
219
ischemia
218
renal failure
211
depression
206
heart disease
205
hyperlipoproteinemia
195
osteoporosis
189
tumor
181
arteriosclerosis
179
anemia
176
cirrhosis
176
hyperuricemia
172
glomerulosclerosis
170
more...
Symptom
overweight
281
angina
207
pain
153
hepatomegaly
88
chest pain
76
abdominal pain
76
fatigue
72
headache
69
weakness
68
diarrhea
63
vomiting
48
nausea
41
hypoproteinemia
38
anesthesia
37
hepatosplenomegaly
35
dyspnea
34
seizures
34
constipation
33
myalgia
29
vertigo
25
anorexia
25
flushing
20
cough
19
dizziness
19
cachexia
18
starvation
17
dysarthria
15
discomfort
15
numbness
15
polyuria
15
shortness of breath
15
splenomegaly
15
discomfort
14
ataxia
14
collapse
14
respiratory distress
14
insomnia
14
sleepiness
14
tremor
13
spasm
13
more...
Drug
Cardiovasc
336
niacin
98
Simvastatin
95
vitamin E
90
Dermatol
79
Nephron
56
Nephron
51
Dial
50
Gemfibrozil
43
Monit
42
Lovastatin
37
Pravastatin
37
ascorbate
37
ROS
34
Bezafibrate
30
lysine
28
Vitamin E
27
Rosuvastatin
26
Ezetimibe
24
caffeine
22
Tacrolimus
22
Ethanol
22
Fructose
21
nitroglycerin
21
EPA
19
Clofibrate
18
Glucagon
18
Albumin
17
Adriamycin
16
Vitamin A
15
Kenyan
13
Neoral
12
Propofol
12
Bifidobacterium
11
MAP
11
ADM
10
CTX
10
Estrogens
10
Colesevelam
10
PTH
10
more...
Enzyme
lipoprotein lipase
454
superoxide dismutase
240
alanine aminotransferase
234
lipase
228
aspartate aminotransferase
188
AMP-activated protein kinase
148
catalase
139
ACE
103
creatine kinase
101
glutathione peroxidase
101
renin
100
protein kinase
99
mitogen-activated protein kinase
94
calcineurin
81
alkaline phosphatase
78
AMPK
76
AST
73
AMPK
72
3-hydroxy-3-methylglutaryl coenzyme A reductase
69
lactate dehydrogenase
65
cholesterol acyltransferase
65
thrombin
64
acetyl-CoA carboxylase
58
CYP7A1
58
tissue plasminogen activator
54
glucose-6-phosphatase
53
ERK
51
LPL
51
peroxidase
46
gamma-glutamyl transpeptidase
39
reverse transcriptase
38
protein kinase C
38
CPT
37
lecithin:cholesterol acyltransferase
33
NADPH oxidase
32
3-hydroxy-3-methylglutaryl-CoA reductase
32
caspase-3
30
CAD
30
CAD
30
CAD
30
more...
Compound
glucose
2113
Clin
1534
Dec
1151
Cardiol
486
water
366
creatinine
354
calcium
351
oxygen
309
DNA
264
Cholesterol
250
sodium
234
nitric oxide
213
Insulin
212
ethanol
189
acetate
153
urea
139
TNF
133
nicotinic acid
119
phosphate
113
GSH
110
GSH
110
salt
109
nitrogen
106
homocysteine
106
arginine
106
nicotinic acid
105
ATP
103
glycerol
101
nicotinic acid
99
nicotinic acid
99
CoA
95
sulfate
95
His
91
Atorvastatin
81
potassium
81
iron
73
palmitic acid
73
Triton
71
galactose
63
Triton WR-1339
61
more...