Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020473 (hyperlipidemia)
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A discussion of which risk factors have been established as significant in prescribing O.C.s (oral contraceptives) is presented. The estrogen component of O.C.s influences the vitamin K dependent coagulation factors II, VII, IX, and X and causes disturbances in hemodynamics, leading to such illnesses as thromboembolism and myocardial infarction. 5% of O.C. users develop hypertension in the first 5 years of use. Previous cardiovascular illness, hypertension, vascular disorders, and other conditions are considered contraindications to O.C. use. Women who smoke, get migrane headaches, or who are over 35 years of age more often develop cardiovascular illness during O.C. use. Obesity, diabetes and hyperlipidemia are among the various risk factors that are related to developing cardiovascular illness or hypertension during O.C. use. O.C. users also can develop gall bladder illnesses; cholcystitis and cholelithiasis are contraindications to O.C. use. Post-pill amenorrhea occurs in .8-1% of O.C. users. O.C. users should undergo gynecological and medical checkups every six months; special consideration should be given if any of the risk factors are present.
Med Welt 1980 May 02
PMID:[Contraception in female risk patients]. 740 70