Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020473 (hyperlipidemia)
 15,891 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We developed a latex turbidometric immunoassay(LTIA) for elastase 1. The precisions were 1.0-2.8% intra-run and 1.2-2.9% inter-day. The dilution test showed good linearity between 80-4000 ng/dl. There was interference by bilirubin, hemoglobin, lipemia or rheumatoid factor. Serum and plasma elastase 1 measured by LTIA(y) showed significant correlations with those by RIA(x) (serum: y = 0.98x--18, r = 0.980, n = 64, plasma: y = 0.96x--19, r = 0.976, n = 61). It was confirmed that the values were elevated in patients with pancreatic disease compared to the normal level. These results demonstrate that the determination of elastase 1 in plasma or serum by this method is useful, simple and time-saving, when compared with that by RIA.
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PMID:[Determination of elastase 1 in plasma or serum by latex turbidometric immunoassay with automatic analyzer]. 1201 17