Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020440 (hypercapnia)
7,939 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CO2 2044
Sep 581
hemoglobin 133
MRI 125
Mol 123
ATP 116
COPD 105
CBF 94
carbonic anhydrase 70
nitric oxide synthase 66
REM 54
She 52
GABA 50
cage 48
ATPase 47
insulin 45
Phox2b 45
CSF 43
NMR 41
renin 39
ANOVA 35
MAC 32
substance P 30
Mal 28
cyclooxygenase 27
cytokine 27
MAP 27
Pol 26
angiotensin II 26
superoxide dismutase 25
albumin 25
tyrosine hydroxylase 22
c-fos 22
ASA 22
orexin 21
vasopressin 20
ADP 20
CA1 19
CPAP 19
arginine vasopressin 19
opioid receptor 18
Gen 18
beta-endorphin 18
bradykinin 17
FEV 17
serum albumin 17
5-hydroxytryptamine 17
P50 16
erythropoietin 16
endothelin-1 16
creatine kinase 16
P100 15
NMDA receptor 14
neuronal nitric oxide synthase 14
TASK-1 14
catalase 14
olfactory 13
reserved 13
gut 13
axonal 13
ionotropic 12
tumor necrosis factor 12
NADH 12
adenosine receptor 12
lipopolysaccharide 11
SAP 11
AMP 11
ASL 11
calcitonin 11
leptin 11
IL-6 10
NHE3 10
growth hormone 10
phosphodiesterase 10
SIDS 10
Orexin 10
proximal tubule 9
ATA 9
homeobox 9
calcium channel 9
more...
Disease
chronic obstructive pulmonary disease 459
respiratory failure 415
respiratory acidosis 384
depression 350
hypertension 301
obstructive sleep apnea 282
sleep apnea 246
stroke 220
ischemia 184
pulmonary hypertension 159
obesity 153
asthma 123
lung disease 111
ARF 110
COPD 105
emphysema 103
heart failure 100
alkalosis 96
pneumonia 94
SEM 93
cold 81
polycystic ovary syndrome 81
cor pulmonale 81
cerebral ischemia 78
sudden infant death syndrome 76
adult respiratory distress syndrome 73
pneumothorax 73
pulmonary edema 67
coma 54
sepsis 50
tumor 49
sepsis 46
metabolic alkalosis 46
diabetes 45
right heart failure 43
cystic fibrosis 39
malignant hyperthermia 39
hyperglycemia 38
Congenital central hypoventilation syndrome 38
cancer 35
respiratory disease 35
myopathy 34
anemia 33
bronchopulmonary dysplasia 33
hypoglycemia 33
MAC 32
NAME 32
Thorax 32
status asthmaticus 31
prematurity 31
cognitive impairment 30
congestive heart failure 29
chronic bronchitis 29
cardiovascular disease 28
Alzheimer's disease 28
heart disease 28
lactic acidosis 28
myocardial ischemia 28
subarachnoid hemorrhage 27
sleep disorders 26
migraine 25
hernia 25
pH increased 24
bronchospasm 23
fits 23
ventricular hypertrophy 23
immaturity 21
influenza 21
dementia 21
bronchiolitis 19
amyotrophic lateral sclerosis 19
atherosclerosis 18
DM1 18
Obesity hypoventilation syndrome 18
encephalopathy 18
hypothyroidism 18
muscular dystrophy 17
panic attacks 17
panic disorder 17
scoliosis 17
more...
Symptom
hypercapnia 7939
anesthesia 620
hypocapnia 471
hyperoxia 344
dyspnea 220
respiratory distress 187
fatigue 134
hypothermia 117
weakness 103
pain 92
seizures 86
collapse 73
analgesia 71
cough 66
sleepiness 62
tachypnea 53
headache 48
discomfort 43
discomfort 43
snoring 43
breath holding 34
cyanosis 31
acidity 23
exhaustion 23
stridor 20
hunger 20
muscle rigidity 18
vomiting 18
agitation 16
overweight 14
Sedation 14
hypotonia 13
spasm 12
twitching 11
CSR 11
wheezing 10
regurgitation 10
nausea and vomiting 10
shortness of breath 10
sinus pressure 10
dizziness 9
diarrhea 9
functional recovery 8
tremor 8
nausea 8
bradypnea 8
lethargy 8
exertional dyspnea 8
syncope 7
abnormal breathing 7
hypersomnia 7
hemoptysis 7
insomnia 7
Anoxia 6
Periodic breathing 6
sneezing 6
Gasping 5
ophthalmoplegia 5
orthopnea 5
flushing 5
chest pain 5
Postoperative pain 4
acute stress 4
hoarseness 4
hemiplegia 4
labored breathing 4
ataxia 4
starvation 4
sore throat 4
angina 3
oliguria 3
tonic-clonic seizure 3
rales 3
myalgia 3
constipation 3
thinning 3
abdominal pain 3
cachexia 3
eds 3
Biot's breathing 2
more...
Drug
Cardiovasc 45
CSF 43
MAP 34
caffeine 32
Indomethacin 22
nitroglycerin 17
Monit 16
NADH 12
Propofol 11
Nephron 11
Fentanyl 10
Amiloride 9
Asthma 8
Dial 8
Amiloride 8
Theophylline 8
Helium 8
lysine 7
EPI 6
Atropine 6
Histamine 6
Clonidine 6
DM1 5
SF6 5
Ethanol 5
NH3 5
CPR 5
Diamox 4
Angiotensin II 4
ascorbate 4
ENT 4
Portal 4
MgSO4 4
Domperidone 4
Doxapram 3
Heme 3
DHT 3
ICI 3
IPD 3
Phosphoramidon 3
Nitric Oxide 3
ROS 3
Sodium nitroprusside 3
Frontal 3
FeCl3 3
vitamin E 3
Bupivacaine 3
Papaverine 2
Thiopentone 2
CoCl2 2
HCH 2
Digitalis 2
Arfonad 2
Kainic acid 2
DHT 2
9-THC 2
Reserpine 2
citric acid 2
CoCl2 2
Ringer's solution 2
CTX 2
LCBF 2
Butorphanol 2
Methylene blue 2
Salbutamol 2
Phentolamine 2
Sinemet 2
Dantrolene sodium 2
ETA 2
Ouabain 2
Innovar 2
SBT 2
Ammonium chloride 2
Carbenoxolone 2
Arfonad 2
Albumin 2
Diurnal 2
Viagra 1
Depo-Provera 1
NaI 1
more...
Enzyme
carbonic anhydrase 71
ATPase 48
renin 39
NO synthase 34
MAP 27
superoxide dismutase 26
creatine kinase 22
tyrosine hydroxylase 22
catalase 17
protein kinase 16
protein kinase C 16
ERK 14
mitogen-activated protein kinase 12
acetylcholinesterase 10
NOS 10
phosphodiesterase 10
tryptophan hydroxylase 9
AMP-activated protein kinase 9
peroxidase 8
glutathione peroxidase 8
ACE 8
guanylate cyclase 8
caspase-3 7
lactate dehydrogenase 7
adenosine deaminase 6
adenosine deaminase 6
complex I 6
heme oxygenase 6
alkaline phosphatase 5
CPR 5
PRA 5
aspartate aminotransferase 5
cholinesterase 5
phospholipase C 4
phosphofructokinase 4
focal adhesion kinase 4
AMPK 4
alcohol dehydrogenase 4
choline acetyltransferase 4
endothelin-converting enzyme 4
citrate synthase 4
prostaglandin synthetase 4
ADH 4
AMPK 4
cytochrome oxidase 4
elastase 3
proteasome 3
adenylate cyclase 3
lysozyme 3
monoamine oxidase 3
CD10 3
phospholipase A2 3
glutamine synthetase 3
alanine aminotransferase 3
CPT 3
hyaluronidase 3
hyaluronidase 3
luciferase 3
CaMKII 3
xanthine oxidase 3
MIP 3
lipoxygenase 3
urokinase-type plasminogen activator 3
CCS 3
pyruvate dehydrogenase 2
trypsin 2
ornithine decarboxylase 2
chalcone synthase 2
pyruvate dehydrogenase 2
CPT 2
SPT 2
arginase 2
alpha-glucosidase 2
hexokinase 2
glucose-6-phosphate dehydrogenase 2
pyruvate dehydrogenase 2
NADPH oxidase 2
tissue plasminogen activator 2
PKG 2
CDH 2
more...
Compound
CO2 2752
oxygen 1639
Dec 552
water 381
Clin 328
sodium 272
carbonate 163
nitric oxide 156
Cereb 148
glucose 139
calcium 133
ATP 116
hydrogen 96
arginine 87
potassium 77
nitrogen 75
HCO 63
glutamate 63
5-HT 54
GABA 52
noradrenaline 51
GABA 51
N2O 48
cyanide 45
ammonia 38
prostacyclin 35
HCl 34
acetate 34
ethanol 33
phosphate 32
caffeine 32
phosphocreatine 31
ammonium 31
MAP 29
Naloxone 29
Acetazolamide 26
cAMP 26
His 26
salt 25
iron 24
aldosterone 24
ASA 23
Cardiol 23
ADP 22
Indomethacin 22
DNA 21
ADP 20
glutamine 20
ADP 20
ACh 20
alanine 19
MCA 18
MCA 18
Halothane 17
urea 16
Adrenal 16
bromide 16
phosphorus 16
NH2 16
Dopamine 15
Theophylline 15
sulfate 15
AMP 14
NMDA 14
cGMP 14
tyrosine 13
gamma-aminobutyric acid 13
Morphine 13
DDVP 12
NADH 12
creatinine 12
Nicotine 12
DPG 11
nitrate 11
tryptophan 11
Propofol 11
DPG 11
Neuronal 11
lysine 10
galactose 10
more...