Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020440 (hypercapnia)
 7,939 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CO2 2044
Sep 581
hemoglobin 133
MRI 125
Mol 123
ATP 116
COPD 105
CBF 94
carbonic anhydrase 70
nitric oxide synthase 66
REM 54
She 52
GABA 50
cage 48
ATPase 47
insulin 45
Phox2b 45
CSF 43
NMR 41
renin 39
ANOVA 35
MAC 32
substance P 30
Mal 28
cytokine 27
MAP 27
cyclooxygenase 27
angiotensin II 26
Pol 26
superoxide dismutase 25
albumin 25
tyrosine hydroxylase 22
c-fos 22
ASA 22
orexin 21
ADP 20
vasopressin 20
arginine vasopressin 19
CA1 19
CPAP 19
opioid receptor 18
beta-endorphin 18
Gen 18
serum albumin 17
bradykinin 17
5-hydroxytryptamine 17
FEV 17
endothelin-1 16
creatine kinase 16
P50 16
erythropoietin 16
P100 15
catalase 14
neuronal nitric oxide synthase 14
NMDA receptor 14
TASK-1 14
gut 13
axonal 13
reserved 13
olfactory 13
adenosine receptor 12
tumor necrosis factor 12
NADH 12
ionotropic 12
lipopolysaccharide 11
ASL 11
SAP 11
AMP 11
calcitonin 11
leptin 11
phosphodiesterase 10
SIDS 10
NHE3 10
growth hormone 10
IL-6 10
Orexin 10
NTS 9
calcium channel 9
homeobox 9
muscarinic receptor 9
ATA 9
DMO 9
glutamate receptor 9
P2X 9
ICP 9
tryptophan hydroxylase 9
GABA(A) receptor 9
thyroid hormone 9
proximal tubule 9
collagen 9
inducible nitric oxide synthase 8
Na(+)/K(+)-ATPase 8
caspase-3 8
ET-1 8
interleukin-6 8
prolactin 8
P2X2 8
myoglobin 8
P10 8
glutathione peroxidase 8
inward rectifier 8
parathyroid hormone 7
Net 7
cardiac muscle 7
5-HT1A 7
ABG 7
NHE1 7
LPS 7
ACTH 7
TNF 7
MAPK 7
Ang II 7
atrial natriuretic peptide 7
Spin 7
guanylate cyclase 7
carp 7
Bcl-2 7
P12 7
JAMA 7
PGF 7
glial fibrillary acidic protein 6
P15 6
calmodulin 6
p38 6
collecting duct 6
endothelial nitric oxide synthase 6
adenosine deaminase 6
PKC 6
vascular endothelial growth factor 6
myosin 6
Kir4.1 6
vascular endothelium 6
penumbra 6
EPI 6
glucagon 6
C-reactive protein 6
Carbonic anhydrase 6
dilute 6
lactate dehydrogenase 6
AMP-activated protein kinase 6
soluble adenylyl cyclase 6
HO-2 6
COX-2 5
cyclooxygenase-2 5
CBD 5
galanin 5
PRA 5
acetylcholinesterase 5
heme oxygenase-1 5
TNF-alpha 5
Kir6.2 5
NHE2 5
Kir5.1 5
ryanodine receptor 5
DM1 5
alkaline phosphatase 5
somatostatin 5
CCA 5
5-HT2 receptor 5
cytochrome 5
more...
Disease
chronic obstructive pulmonary disease 459
respiratory failure 415
respiratory acidosis 384
depression 350
hypertension 301
obstructive sleep apnea 282
sleep apnea 246
stroke 220
ischemia 184
pulmonary hypertension 159
obesity 153
asthma 123
lung disease 111
ARF 110
COPD 105
emphysema 103
heart failure 100
alkalosis 96
pneumonia 94
SEM 93
polycystic ovary syndrome 81
cor pulmonale 81
cold 81
cerebral ischemia 78
sudden infant death syndrome 76
adult respiratory distress syndrome 73
pneumothorax 73
pulmonary edema 67
coma 54
sepsis 50
tumor 49
sepsis 46
metabolic alkalosis 46
diabetes 45
right heart failure 43
cystic fibrosis 39
malignant hyperthermia 39
Congenital central hypoventilation syndrome 38
hyperglycemia 38
cancer 35
respiratory disease 35
myopathy 34
hypoglycemia 33
anemia 33
bronchopulmonary dysplasia 33
NAME 32
Thorax 32
MAC 32
status asthmaticus 31
prematurity 31
cognitive impairment 30
chronic bronchitis 29
congestive heart failure 29
cardiovascular disease 28
lactic acidosis 28
myocardial ischemia 28
heart disease 28
Alzheimer's disease 28
subarachnoid hemorrhage 27
sleep disorders 26
migraine 25
hernia 25
pH increased 24
fits 23
ventricular hypertrophy 23
bronchospasm 23
immaturity 21
dementia 21
influenza 21
amyotrophic lateral sclerosis 19
bronchiolitis 19
DM1 18
Obesity hypoventilation syndrome 18
atherosclerosis 18
encephalopathy 18
hypothyroidism 18
ventricular fibrillation 17
scoliosis 17
panic attacks 17
panic disorder 17
muscular dystrophy 17
mole 16
mole 16
epilepsy 16
Parkinson's disease 15
moyamoya 15
Central sleep apnea 15
Duchenne muscular dystrophy 15
tension pneumothorax 15
myocardial infarction 14
Carotid body 14
Carotid body 14
Carotid body 14
vascular disease 14
polycythemia 14
renal failure 14
dehydration 13
malnutrition 13
coronary artery disease 13
intraocular pressure 13
Ondine's curse 13
raised intracranial pressure 13
Evans 13
Ondine's curse 13
sleep disturbances 12
mountain sickness 12
Syndrome 12
Schmidt 12
pulmonary tuberculosis 12
Thoracic 12
Diaphragm 12
pulmonary embolism 12
bronchitis 11
hyaline membrane disease 11
bronchitis 11
left ventricular failure 10
gastroesophageal reflux disease 10
dysphagia 10
morbid obesity 10
bends 10
bronchiectasis 10
cardiomyopathy 10
polio 10
tuberculosis 10
confusion 9
myasthenia gravis 9
type 2 diabetes 9
Brown 9
rare disease 9
hyperosmolality 9
metabolic syndrome 9
brain edema 9
vascular dilation 9
retinopathy of prematurity 9
neuropathy 9
fluid overload 9
tetraplegia 9
ICP 9
cerebral vasospasm 8
glaucoma 8
renal disease 8
muscular atrophy 8
carcinoma 8
neurological disease 8
respiratory infection 8
Esophageal 8
pulmonary fibrosis 8
plaque 7
infectious diseases 7
virus infection 7
AMD 7
delirium 7
cornea 7
aggression 7
hyperbilirubinemia 7
acute myocardial infarction 7
bacterial infection 7
disinhibition 7
genetic disorder 7
autonomic neuropathy 7
more...
Symptom
hypercapnia 7939
anesthesia 620
hypocapnia 471
hyperoxia 344
dyspnea 220
respiratory distress 187
fatigue 134
hypothermia 117
weakness 103
pain 92
seizures 86
collapse 73
analgesia 71
cough 66
sleepiness 62
tachypnea 53
headache 48
discomfort 43
snoring 43
discomfort 43
breath holding 34
cyanosis 31
exhaustion 23
acidity 23
hunger 20
stridor 20
vomiting 18
muscle rigidity 18
agitation 16
overweight 14
Sedation 14
hypotonia 13
spasm 12
CSR 11
twitching 11
regurgitation 10
shortness of breath 10
wheezing 10
nausea and vomiting 10
sinus pressure 10
diarrhea 9
dizziness 9
nausea 8
functional recovery 8
tremor 8
exertional dyspnea 8
bradypnea 8
lethargy 8
hypersomnia 7
insomnia 7
syncope 7
hemoptysis 7
abnormal breathing 7
Periodic breathing 6
Anoxia 6
sneezing 6
flushing 5
ophthalmoplegia 5
Gasping 5
orthopnea 5
chest pain 5
starvation 4
hoarseness 4
sore throat 4
ataxia 4
Postoperative pain 4
labored breathing 4
hemiplegia 4
acute stress 4
rales 3
angina 3
cachexia 3
oliguria 3
thinning 3
abdominal pain 3
tonic-clonic seizure 3
myalgia 3
constipation 3
eds 3
numbness 2
nasal congestion 2
paresthesia 2
hepatomegaly 2
chest tightness 2
productive cough 2
asthenia 2
presyncope 2
hypoproteinemia 2
back pain 2
vertigo 2
shoulder pain 2
lightheadedness 2
Biot's breathing 2
spasticity 2
ENT 2
paresis 2
clonus 2
clubbing 2
chronic cough 2
phosphatemia 2
muscle cramps 2
bloating 2
dysarthria 2
Organ failure 2
bedwetting 1
rundown 1
blurred vision 1
bigeminal 1
pallor 1
memory loss 1
sighing 1
Hudson 1
breakthrough pain 1
Action myoclonus 1
aphonia 1
arthralgia 1
ketonuria 1
acute abdominal pain 1
Hoover's sign 1
leg edema 1
blackout 1
emaciation 1
retching 1
Postoperative nausea 1
Apneusis 1
Jaw stiffness 1
Postoperative nausea and vomiting 1
acute pain 1
distraction 1
hypertonia 1
incoordination 1
Dyspnea at rest 1
Neuropathic pain 1
Respiratory symptoms 1
cerebellar ataxia 1
Paroxysmal hypertension 1
acute abdomen 1
apathy 1
chorea 1
Lung hyperinflation 1
Respiratory abnormalities 1
physical appearance 1
tense 1
myoclonus 1
Chronic hypoventilation 1
general problem 1
Acute dyspnea 1
splenomegaly 1
chronic back pain 1
Poor sleep 1
alexithymia 1
neuralgia 1
Orthostasis 1
Increased work of breathing 1
rhinorrhea 1
Stiffness 1
asterixis 1
neurological disability 1
Induced hypothermia 1
Diaphragmatic weakness 1
more...
Drug
Cardiovasc 45
CSF 43
MAP 34
caffeine 32
Indomethacin 22
nitroglycerin 17
Monit 16
NADH 12
Propofol 11
Nephron 11
Fentanyl 10
Amiloride 9
Dial 8
Helium 8
Asthma 8
Theophylline 8
Amiloride 8
lysine 7
Clonidine 6
Atropine 6
EPI 6
Histamine 6
CPR 5
DM1 5
NH3 5
SF6 5
Ethanol 5
Portal 4
ENT 4
Domperidone 4
ascorbate 4
Diamox 4
MgSO4 4
Angiotensin II 4
Frontal 3
FeCl3 3
ICI 3
IPD 3
DHT 3
Doxapram 3
vitamin E 3
Sodium nitroprusside 3
Heme 3
Phosphoramidon 3
Nitric Oxide 3
ROS 3
Bupivacaine 3
Methylene blue 2
Papaverine 2
Reserpine 2
Kainic acid 2
citric acid 2
Carbenoxolone 2
Ammonium chloride 2
CTX 2
LCBF 2
Arfonad 2
Butorphanol 2
Arfonad 2
Phentolamine 2
9-THC 2
ETA 2
Dantrolene sodium 2
Thiopentone 2
Ouabain 2
Digitalis 2
Innovar 2
SBT 2
HCH 2
DHT 2
Salbutamol 2
CoCl2 2
Albumin 2
Diurnal 2
CoCl2 2
Sinemet 2
Ringer's solution 2
Viagra 1
CTX 1
NaI 1
Iloprost 1
NaI 1
Morphine sulfate 1
Fluorescein 1
Rosiglitazone 1
ABC 1
Asn 1
Enoximone 1
Zonisamide 1
7-Nitroindazole 1
Fraction 1
Aramine 1
Piracetam 1
Pentothal 1
Forskolin 1
Adenosine triphosphate 1
ETS 1
CaCl2 1
Oxaliplatin 1
PFA 1
Lugol's solution 1
Nephron 1
Methohexitone 1
MRC 1
Adenosine deaminase 1
2-Methoxyestradiol 1
DPA 1
NaI 1
Hypaque 1
Fenoldopam 1
Serum albumin 1
Sodium acetate 1
Prulifloxacin 1
Phenytoin 1
ROC 1
Dormicum 1
ampicillin 1
Ipratropium bromide 1
Fluorescein 1
CDP 1
Dakar 1
Bumetanide 1
Leaf 1
Flurazepam 1
Prozac 1
Vectarion 1
Dimexidum 1
Cibenzoline 1
TTC 1
Depo-Provera 1
IL-2 1
CAM 1
Pentamorphone 1
FLP 1
Triflocin 1
Ranitidine 1
Ritanserin 1
Acacia 1
Glutathione 1
EE2 1
CFX 1
CTX 1
Hypaque 1
Triazolam 1
C3H6 1
Indocyanine green 1
CaCl2 1
EPA 1
Aramine 1
Magnesium sulfate 1
Viagra 1
CaCl2 1
Aminoguanidine 1
Pregabalin 1
Timolol 1
metformin hydrochloride 1
Ketoconazole 1
PCB 1
NaI 1
uPA 1
more...
Enzyme
carbonic anhydrase 71
ATPase 48
renin 39
NO synthase 34
MAP 27
superoxide dismutase 26
tyrosine hydroxylase 22
creatine kinase 22
catalase 17
protein kinase C 16
protein kinase 16
ERK 14
mitogen-activated protein kinase 12
NOS 10
phosphodiesterase 10
acetylcholinesterase 10
tryptophan hydroxylase 9
AMP-activated protein kinase 9
guanylate cyclase 8
peroxidase 8
ACE 8
glutathione peroxidase 8
lactate dehydrogenase 7
caspase-3 7
adenosine deaminase 6
complex I 6
adenosine deaminase 6
heme oxygenase 6
cholinesterase 5
PRA 5
alkaline phosphatase 5
CPR 5
aspartate aminotransferase 5
AMPK 4
phospholipase C 4
choline acetyltransferase 4
phosphofructokinase 4
prostaglandin synthetase 4
endothelin-converting enzyme 4
citrate synthase 4
cytochrome oxidase 4
alcohol dehydrogenase 4
AMPK 4
focal adhesion kinase 4
ADH 4
MIP 3
adenylate cyclase 3
CPT 3
luciferase 3
alanine aminotransferase 3
urokinase-type plasminogen activator 3
glutamine synthetase 3
CD10 3
phospholipase A2 3
hyaluronidase 3
proteasome 3
hyaluronidase 3
lipoxygenase 3
elastase 3
CaMKII 3
xanthine oxidase 3
monoamine oxidase 3
lysozyme 3
CCS 3
pyruvate dehydrogenase 2
adenosine kinase 2
glutathione S-transferase 2
thrombin 2
thromboplastin 2
AST 2
glucose-6-phosphate dehydrogenase 2
tissue plasminogen activator 2
CDH 2
NADPH oxidase 2
hexokinase 2
pyruvate dehydrogenase 2
PKG 2
NADPH oxidase 2
arginase 2
trypsin 2
ornithine decarboxylase 2
chalcone synthase 2
SPT 2
CPT 2
glutaminase 2
pyruvate dehydrogenase 2
SPT 2
reverse transcriptase 2
alpha-glucosidase 2
CPT 2
kallikrein 2
15-hydroxyprostaglandin dehydrogenase 1
gamma-glutamyl transpeptidase 1
tauropine dehydrogenase 1
MsrB 1
glyceraldehyde-3-phosphate dehydrogenase 1
PPH 1
Alternating 1
succinate dehydrogenase 1
transcriptase 1
FAST 1
PAT 1
aldehyde dehydrogenase 1
papain 1
ATP synthase 1
pyruvate carboxylase 1
demethylase 1
RNA polymerase 1
glyceraldehyde-3-phosphate dehydrogenase 1
pyruvate kinase 1
aldolase 1
p100 1
glyceraldehyde-3-phosphate dehydrogenase 1
prolyl hydroxylase 1
caspase-7 1
glycerol-3-phosphate dehydrogenase 1
glucose oxidase 1
NADPH-diaphorase 1
phosphorylase 1
Tpa 1
isocitrate dehydrogenase 1
diaphorase 1
deaminase 1
BAL 1
CAO 1
NADH dehydrogenase 1
IKK 1
type III procollagen 1
meprin 1
glycerol-3-phosphate dehydrogenase 1
glyceraldehyde-3-phosphate dehydrogenase 1
ceruloplasmin 1
PHT 1
phosphoglucose isomerase 1
lysyl oxidase 1
isocitrate dehydrogenase 1
RNase 1
ricin 1
collagenase 1
ACS 1
histidine decarboxylase 1
dimethylarginine dimethylaminohydrolase 1
caspase-7 1
pepsin 1
NQO2 1
C3 convertase 1
heparinase 1
PARP 1
DOPA decarboxylase 1
PAH 1
glyceraldehyde-3-phosphate dehydrogenase 1
soluble epoxide hydrolase 1
peroxiredoxin 1
RNase 1
AMP-activated kinase 1
Compound
CO2 2752
oxygen 1639
Dec 552
water 381
Clin 328
sodium 272
carbonate 163
nitric oxide 156
Cereb 148
glucose 139
calcium 133
ATP 116
hydrogen 96
arginine 87
potassium 77
nitrogen 75
HCO 63
glutamate 63
5-HT 54
GABA 52
GABA 51
noradrenaline 51
N2O 48
cyanide 45
ammonia 38
prostacyclin 35
acetate 34
HCl 34
ethanol 33
caffeine 32
phosphate 32
phosphocreatine 31
ammonium 31
Naloxone 29
MAP 29
Acetazolamide 26
cAMP 26
His 26
salt 25
aldosterone 24
iron 24
Cardiol 23
ASA 23
Indomethacin 22
ADP 22
DNA 21
glutamine 20
ACh 20
ADP 20
ADP 20
alanine 19
MCA 18
MCA 18
Halothane 17
NH2 16
Adrenal 16
bromide 16
urea 16
phosphorus 16
Dopamine 15
Theophylline 15
sulfate 15
NMDA 14
AMP 14
cGMP 14
tyrosine 13
Morphine 13
gamma-aminobutyric acid 13
Nicotine 12
creatinine 12
NADH 12
DDVP 12
tryptophan 11
Propofol 11
DPG 11
DPG 11
nitrate 11
Neuronal 11
galactose 10
Muscimol 10
Tris 10
Gly 10
tryptophan 10
lysine 10
tryptophan 10
tryptophan 10
copper 10
Isoproterenol 10
Norepinephrine 10
ATA 9
methionine 9
DMO 9
prostaglandin F1 9
PGE2 9
2-hydroxyethyl 9
Adenosine 9
pyridine 9
Optimal 9
Retinal 9
Lactate 8
Amiloride 8
Phe 8
Dial 8
HEPES 8
H2O2 8
2,3-diphosphoglycerate 8
mercury 8
SO2 8
Mg2+ 8
Asp 8
Diazepam 8
TNF 7
aspartic acid 7
cysteine 7
prostaglandin E1 7
fluorine 7
Isoflurane 7
glutamic acid 7
PEG 7
AMPA 7
Histamine 7
Aminophylline 7
5-hydroxytryptophan 7
6-12 7
Pentobarbital 7
Bicuculline 7
acetic acid 6
ACTH 6
Droperidol 6
aspartic acid 6
Verapamil 6
aspartic acid 6
DMSO 6
carbonic acid 6
cadmium 6
Hypo 6
Progesterone 6
L-DOPA 6
Verapamil 6
Atropine 6
Lidocaine 6
aspartic acid 6
Sevoflurane 6
Maps 6
DIDS 6
Haloperidol 5
Sufentanil 5
A 3 5
Insulin 5
Xenon 5
Pentobarbital 5
carbonic acid 5
carbonic acid 5
Propranolol 5
DTPA 5
carbonic acid 5
carbonic acid 5
carbonic acid 5
carbonic acid 5
Dantrolene 5
more...