Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020440 (hypercapnia)
 7,939 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Poliomyelitis can affect patients with severe hypoxia and hypercapnia. Historically, most of these patients were supported by mechanical ventilation via tracheostomy. However, this procedure can lead to serious complications. Subsequently, non-invasive alternative procedures have been introduced that provide mechanical respiratory support; these include negative pressure ventilators and positive pressure ventilation via a nasal, oral, and oronasal interface. Although these ventilators are effective, various limitations have been noted. The strapless oronasal interface positive pressure ventilator appears to have the fewest limitations, and through the use of advanced dental techniques and improved dental materials, this ventilator is easily fabricated and has been noted by patients to be more comfortable.
Mil Med 1995 Jun
PMID:Comparison of different mechanical ventilators for patients with poliomyelitis. 765 27

Severe acute respiratory syndrome (SARS) is a highly infectious, rapidly progressive, emerging disease. Early diagnosis and preventive measures are key for treatment and minimization of secondary spread. In the context of the armed forces, aggressive containment measures are essential to prevent an outbreak. In this study, we present the first reported case, to our knowledge, of SARS in a naval diver. The special physical requirements for divers and the potential complications associated with deep sea diving necessitate extensive investigation before certification of fitness for diving after SARS. In the early recovery period, potential problems during diving are caused by inadequate lung ventilation in relation to exercise level and increased breathing resistance attributable to weak respiratory muscles, with corresponding risk of hypoxia and hypercapnia, as well as decreased ability to respond to nonrespiratory problems during diving. Problems in the late recovery period include increased risk of diving complications (such as pulmonary barotrauma) resulting from fibrosis and scarring within the lung parenchyma, which are known complications of SARS. From our experience, we suggest that computed tomographic scans of the thorax, lung function tests, and careful follow-up monitoring should play a vital role in the assessment of patients during the convalescent period, before certification of fitness to dive.
Mil Med 2006 Jun
PMID:Severe acute respiratory syndrome in a naval diver. 1680 26