Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020440 (
hypercapnia
)
7,939
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
This paper reviews the effects of exercise and
hypercapnia
on blood flow to the splanchnic circulation. Brief struggling behaviours are known to decrease blood flow to the gut (
GBF
). Likewise, prolonged swimming in unfed fish has been shown to reduce
GBF
in proportion to the increased oxygen uptake. Therefore, the normal postprandial increase in
GBF
theoretically should be impaired whenever fish are active. However, indirect evidence suggests that
GBF
is spared to some degree when fed fish swim continuously but at a cost (10-15%) to their critical swimming speed. Severe respiratory acidosis can be created by the new intensive aquaculture settings that use oxygen injection into re-circulated water. The only study so far to examine the effects of severe
hypercapnia
on
GBF
and its regulation showed that routine
GBF
and alpha-adrenergic control of
GBF
remained normal in unfed white sturgeon (Acipenser transmontanus). However, severe
hypercapnia
produced a hyperactive state and increased sensitivity of
GBF
to struggling. As a result, routine
GBF
was maintained for a short period of time. Thus, environmental changes such as severe
hypercapnia
can indirectly impact
GBF
through altered struggling behaviour, but the implications of the overall reduction in
GBF
to food assimilation have yet to be established.
...
PMID:Gut blood flow in fish during exercise and severe hypercapnia. 1124 44