Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020440 (hypercapnia)
 7,939 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Among the steadily increasing population of surgical older patients than 65 yr are the fast growing group about 85 yr and older. Postoperative averse effects on the cardiac, pulmonary, cerebral and urinary systems are the main concerns for elderly surgical patients who are at high risk. The function capacity of organs reduces with age, resulting in decreased reserve and ability to endure stress. The effect of anesthetics on postoperative delirium has been studied and a leasing hyposthesis has been that offending druha aggravate an age-associated central cholinergic insufficiency. In additional to being linked to narcotics, sedative, and anticholinergics, delirium has been associated with urinary tract infection, pneumonia, hypoxia or hypercarbia, fever, blood loss, and electrolyte disturbances. In this review, we document the incidence of postoperative averse outcomes and discuss way of improving perioperative anaesthesia care for this vulnerable surgical population. There is present possibility anaesthesia in elderly.
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PMID:[Surgery in the elderly]. 1633 36

Meropenam, a beta-lactam antibiotic has been used for severe infections of skin, tissue, intra- abdominal and urogenital infections in hospitalized patients. The common adverse effects reported are diarrhoea, vomiting, rashes and hypersensitivity reactions. Here we report two cases of meropenam induced hypokalemia, wherein, meropenam was prescribed for cellulitis and urinary tract infection in the first and second case respectively. Hypokalemia can manifest as muscular weakness, fatigue, muscle cramps, constipation, ileus, flaccid paralysis, hyporeflexia, hypercapnia, tetany, rhabdomyolysis or respiratory failure. Hence, it is necessary to make physicians aware of such an adverse effect which can develop with meropenam.
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PMID:Meropenem Induced Hypokalemia. 2896 83