Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020440 (
hypercapnia
)
7,939
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Despite widespread prevalence of
sleepwalking
, its etiology and pathophysiology are not well understood. However, there is some evidence that
sleepwalking
can be precipitated by sleep-disordered breathing. A hypothesis is proposed that serotonergic system may be a link between sleep-disordered breathing and
sleepwalking
. Serotonergic neurons meet basic requirements for such a role because they are activated by
hypercapnia
, provide a tonic excitatory drive that gates afferent inputs to motoneurons, and the activity of serotonergic neurons can be dissociated from the level of arousal. This paper discusses also drug-induced
somnambulism
and co-occurrence of
sleepwalking
and other disorders such as migraine and febrile illness.
...
PMID:Serotonergic hypothesis of sleepwalking. 1553 5
