Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020440 (hypercapnia)
 7,939 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In metabolic alkalosis, a compensatory decrease in alveolar ventilation with hypercapnia has been noted only rarely. We recently managed a patient with gastric outlet obstruction from a duodenal ulcer who survived after arriving in the emergency room comatose with severe hypochloremic metabolic alkalosis, compensatory hypoventilation, and hypercapnia. We know of no report in the English literature of a patient with gastric outlet obstruction having a respiratory acidosis or hypochloremia as severe as that in our patient. Proper understanding of the pathophysiology of primary metabolic alkalosis due to gastric losses is necessary to correct the acid-base abnormalities quickly and to restore normal alveolar ventilation.
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PMID:Marked hypochloremic metabolic alkalosis with severe compensatory hypoventilation. 376 30

A 72-year old lady suffering from coronary heart disease was admitted with acute abdominal pain. Laparoscopy was performed and revealed perforation of a duodenal ulcer. The surgeon decided to suture the perforation via laparoscope. After an uncomplicated start he had to finish the laparoscopic procedure because of a massive hypercapnia and a developing subcutaneous emphysema. Laparotomy showed an iatrogenic perforation of the right diaphragm. A chest drain was inserted; after suturing of the perforated ulcer the abdomen was closed. The further hospital stay was uneventful. The possible causes for the increasing hypercapnia are discussed. We suggest close monitoring of patients during laparoscopy including capnometry and the anaesthesist should be aware of rare complications.
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PMID:[Capnothorax and subcutaneous emphysema in attempted laparoscopic suture of duodenal ulcer]. 794 6