Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020438 (hypercalciuria)
 2,502 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
vitamin D-dependent calcium binding protein calbindin 13.6
CLDN19 12.8
SLC34A3 12.7
claudin 16 12.7
chloride channel CLC-5 12.6
CLCN5 12.6
Claudin-16 12.6
claudin-19 12.4
CLC-5 11.8
kinesin family member 3B 11.6
NPT-1 11.6
TRPV5 protein 11.6
SLC34A1 11.4
formin binding protein 21 11.3
ClC-5 11.1
SLC12A1 11.0
KCNJ1 10.9
TRPV5 10.8
sodium phosphate transporter 10.6
GalNAc transferase 3 10.5
ATP6V0A4 10.4
claudin-14 10.4
NPT2 10.3
OCRL-1 10.3
ATP6V1B1 10.3
CLCN4 10.2
CLCNKB 10.1
OCRL 10.1
OCRL1 10.0
CLDN10 10.0
barttin 9.9
Oculocerebrorenal syndrome of Lowe 9.9
epithelial calcium channel 9.9
AVP-NPII 9.8
bumetanide-sensitive Na-K-2Cl cotransporter 9.8
TRPV6 protein 9.7
A4GALT 9.7
CaT2 9.6
TGM5 9.5
INPP5B 9.5
calcium-sensing receptor 9.4
CLCN3 9.3
KLHL3 9.3
claudin-10 9.2
NCCT 9.2
25-hydroxyvitamin D3-1alpha-hydroxylase 9.2
transient receptor potential melastatin 6 9.2
NKCC2 9.2
ABCA13 9.2
VDDR 9.1
ENaCalpha 9.1
ROMK 9.1
TRPV6 9.0
TRPM6 9.0
WNK4 9.0
FHH 9.0
Na/Pi-cotransport 8.9
polycystin 2 8.8
ovarian cancer G protein-coupled receptor 1 8.8
ECaC2 8.8
ECaC 8.8
NEDD4-2 8.8
parathyroid hormone receptor 1 8.7
phosphatonin 8.7
SLC12A3 8.6
TRPP2 8.5
PHEX 8.5
calcium sensing receptor 8.5
AP17 8.5
MCD4 8.5
ClC-K2 8.4
CYP24A1 8.4
SLC34A2 8.4
SPAK 8.4
SLC4A1 8.4
CLDN18 8.4
DGKH 8.4
CaSR 8.3
CaT1 8.2
NBCe2 8.2
more...
Disease
hypercalciuria 13.6
Familial hypomagnesaemia-hypercalciuria 13.6
Hypercalciuric rickets 13.6
Microscopic nephrocalcinosis 13.6
HHRH 13.4
SLC34A3, 13.3
Idiopathic hypercalciuria 13.2
Dent's disease 12.5
XLN 12.1
Pituitary microadenoma 12.1
hypophosphaturia 12.0
nephrocalcinosis 11.9
Renal magnesium wasting 11.8
Granulomatous uveitis 11.6
Bilateral hilar adenopathy 11.6
hyperoxaluria 11.3
sponge kidney 11.2
Distal RTA 11.1
Fatty acid deficiency 11.1
Renal tubular dysfunction 11.1
nephrolithiasis 10.9
Distal renal tubular acidosis 10.9
Chronic respiratory acidosis 10.8
glycinuria 10.6
Renal hemosiderosis 10.6
Bartter's syndrome 10.4
demineralization of bone 10.3
uricosuria 10.2
Medullary nephrocalcinosis 10.2
hypokalemic alkalosis 10.1
BSND 10.0
Hypervitaminosis D 9.9
Lymphocytic alveolitis 9.9
Walker carcinoma 256 9.9
cystinuria 9.9
VDD1 9.8
Autosomal recessive hypophosphatemic rickets 9.8
NHPT 9.8
Gitelman syndrome 9.8
urolithiasis 9.8
FBH1 9.8
renal tubular acidosis 9.6
Idiopathic osteoporosis 9.5
Familial hyperparathyroidism 9.5
phosphaturia 9.5
Lowe syndrome 9.5
Gordon's syndrome 9.5
disorders of calcium metabolism 9.4
aminoaciduria 9.4
renal glycosuria 9.3
Enteric hyperoxaluria 9.3
urethrorrhagia 9.3
HVDRR 9.2
familial hypophosphatemia 9.2
hypercalcemia 9.2
Familial hypocalciuric hypercalcemia 9.2
rickets 9.1
Nephrotic range proteinuria 9.1
hyperchloremia 9.0
hypoparathyroidism 8.9
VDDR 8.8
primary hyperparathyroidism 8.8
metabolic alkalosis 8.7
hypermagnesemia 8.6
primary hyperoxaluria 8.6
Granulomatous interstitial nephritis 8.4
HYP 8.4
Fanconi syndrome 8.4
lupus pernio 8.3
APRT deficiency 8.3
hypochloremia 8.3
Burnett 8.3
hereditary anemia 8.2
crystal arthropathy 8.2
ureterolithiasis 8.2
Acute poststreptococcal glomerulonephritis 8.2
osteomalacia 8.2
tetany 8.0
hyperparathyroidism 8.0
hypervitaminosis 8.0
more...
Symptom
urethralgia 12.1
carpopedal spasm 9.1
vaginal itching 8.5
polyuria 8.5
renal colic 8.0
polydipsia 7.4
generalized abdominal pain 7.0
bedwetting 7.0
phosphatemia 6.9
enuresis 6.8
Acute urinary retention 6.7
bone pain 6.5
dysuria 6.5
nocturnal polyuria 6.4
flank pain 6.1
Extrapyramidal symptoms 6.0
urinary frequency 5.1
muscle cramps 4.8
stomach pain 4.7
arm pain 4.7
hyperemesis gravidarum 4.5
decreased appetite 4.4
chronic back pain 4.1
colic 4.0
livedo 3.9
oliguria 3.8
leg pain 3.6
hepatosplenomegaly 3.5
productive cough 3.5
abnormal gait 3.5
abdominal pain 3.5
vomiting 3.4
splenomegaly 3.4
pallor 3.3
myalgia 3.3
hepatomegaly 3.1
abdominal discomfort 2.9
weakness 2.9
back pain 2.9
sneezing 2.7
hypotonia 2.7
fever of unknown origin 2.6
skin irritation 2.6
acidity 2.6
rhinorrhea 2.5
paresthesia 2.4
tachypnea 2.3
constipation 2.3
asthenia 2.3
anorexia 2.2
sore throat 2.2
knee pain 2.2
lethargy 2.2
diarrhea 1.9
arthralgia 1.8
cyanosis 1.8
overweight 1.8
seizures 1.7
nausea 1.7
hypercapnia 1.7
hemiplegia 1.7
dyspnea 1.7
agitation 1.7
apathy 1.6
cough 1.4
numbness 1.3
shortness of breath 1.3
thinning 1.2
cachexia 1.2
fatigue 1.0
vertigo 0.8
pain 0.8
ataxia 0.7
tremor 0.5
syncope 0.5
dizziness 0.4
Ill 0.2
discomfort 0.2
discomfort 0.1
sleepiness -0.0
more...
Drug
Lithostat 13.6
Calcibind 13.6
Potassium citrate 10.9
Uralyt 10.6
Tacalcitol 10.5
Carbetimer 10.3
Bendrofluazide 10.2
Sodium borate 10.2
Metolazone 9.6
Bonefos 9.5
Benazepril hydrochloride 9.5
Lotrel 9.5
Alfacalcidol 9.1
Hydrochlorothiazide 8.6
Cinacalcet 8.5
Chlorothiazide 8.2
Rocaltrol 8.1
Aredia 8.0
PTH 8.0
CTZ 7.9
Tiopronin 7.5
Deflazacort 7.2
Clodronate 6.6
Pyridoxal phosphate 6.5
Teriparatide 6.2
Deferasirox 6.0
Ethane 5.9
Talc 5.9
Ammonium chloride 5.8
EHDP 5.7
DMSA 5.7
Zmax 5.6
Nephron 5.4
Ergosterol 5.3
Auranofin 5.2
Prednisone 5.2
Bumetanide 4.9
Nephron 4.9
APD 4.8
DDAVP 4.7
DDAVP 4.7
Zoledronic acid 4.7
Ketoconazole 4.6
CPM 4.4
Vitamin B 4.3
Growth hormone 4.1
Amiloride 4.1
Growth hormone 4.1
Zoledronic acid 4.0
Indomethacin 3.8
Amiloride 3.8
Methylprednisolone 3.8
FLP 3.6
NAG 3.6
IL-11 3.5
Lactose 3.5
Azithromycin 3.4
Fluconazole 3.3
Vitamin K 3.2
Prednisolone 3.1
Dial 3.0
TAC 3.0
Glucagon 2.8
CTX 2.8
CTX 2.7
citric acid 2.7
Theophylline 2.7
CaCl2 2.6
CaCl2 2.6
CaCl2 2.5
DHT 2.5
Estrogens 2.5
DHT 2.5
pyridoxal phosphate 2.3
Fraction 2.3
ADM 2.0
lactose 1.9
CTX 1.9
MRC 1.9
caffeine 1.8
more...
Enzyme
retinoid isomerase 8.3
5-oxoprolinase 7.2
oxalate decarboxylase 6.9
1-hydroxylase 6.5
arachidonate 5-lipoxygenase 6.4
prostaglandin synthetase 5.8
citrate lyase 5.5
fumarylacetoacetate hydrolase 5.5
nucleotide pyrophosphatase 5.1
AGT 5.0
biotinidase 5.0
dihydropyrimidine dehydrogenase 5.0
prolidase 4.7
alkaline phosphatase 4.6
HK2 4.5
cysteine synthase 4.3
tissue kallikrein 4.3
phytase 4.3
phytase 4.3
CPM 4.2
glutathione synthetase 4.2
glycerol kinase 4.1
sucrase-isomaltase 3.9
urease 3.8
cathepsin K 3.8
urease 3.8
renin 3.7
diacylglycerol kinase 3.7
calcium pump 3.7
carbonic anhydrase 3.4
heparinase 3.3
ACE 3.3
PRA 2.9
lactase 2.6
ADH 2.5
ATPase 2.5
N-acetyltransferase 2.4
sucrase 2.4
asparaginase 2.2
acid phosphatase 2.0
pyruvate dehydrogenase 1.9
pyruvate dehydrogenase 1.9
lactate dehydrogenase 1.6
PAH 1.5
gamma-glutamyl transpeptidase 1.5
CD10 1.4
invertase 1.4
ceruloplasmin 1.3
lysozyme 1.2
pyruvate dehydrogenase 1.2
kallikrein 1.1
creatine kinase 1.0
adenylate cyclase 1.0
caspase-9 0.8
glucose-6-phosphate dehydrogenase 0.7
reverse transcriptase 0.7
xanthine oxidase 0.6
calcineurin 0.6
lipoxygenase 0.5
cytochrome oxidase 0.5
plasmin 0.5
collagenase 0.5
alcohol dehydrogenase 0.5
endonuclease 0.5
transcriptase 0.4
glutathione reductase 0.4
NADPH oxidase 0.3
NADPH oxidase 0.2
protein kinase C 0.0
luciferase -0.0
thromboplastin -0.1
trypsin -0.1
peroxidase -0.4
DNA polymerase -0.4
phosphodiesterase -0.6
aspartate aminotransferase -0.8
glutathione peroxidase -0.8
ERK -0.9
alanine aminotransferase -1.1
protein kinase -1.1
more...
Compound
Thiazide 9.6
Doxercalciferol 9.5
Trichlormethiazide 9.5
Dihydrotachysterol 9.4
B 37 9.1
Succinimide 9.1
oxalate 8.7
Paricalcitol 8.5
Magnesium hydroxide 8.3
Chlorthalidone 8.2
A-14 8.1
Hydrochlorothiazide 8.0
25-dihydroxycholecalciferol 7.7
Vitamin D3 7.3
vitamin D 7.3
Vitamin D3 7.3
Deoxypyridinoline 7.2
NCD 7.1
Aluminum hydroxide 7.0
Tanakan 7.0
Mithramycin 6.9
Triamterene 6.9
Uric acid 6.7
Tolazoline 6.7
Tamsulosin 6.7
Pamidronate 6.6
25-hydroxycholecalciferol 6.3
oxalic acid 6.3
Vitamin D 6.2
Pyridoxine 6.1
5-oxoproline 6.1
5-oxoproline 6.1
calcium 6.0
creatinine 5.9
Cystine 5.9
5-oxoproline 5.9
Ethacrynic acid 5.9
phosphorus 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
oxalic acid 5.8
Inactin 5.8
oxalic acid 5.8
Alendronate 5.6
DMT 5.5
5-oxoproline 5.5
NMN 5.5
Chlorambucil 5.5
Alendronate 5.4
Topiramate 5.4
Salix 5.4
CIT 5.3
Calcitonin 5.3
Celastrol 5.3
Cystine 5.2
HPT 5.2
HPP 5.1
BMD 5.1
phosphate 5.1
DLT 5.1
EHDP 4.9
sodium chloride 4.9
SP-1 4.8
Octreotide 4.7
PSP 4.7
Ketoconazole 4.7
VMA 4.6
DEC 4.6
more...