Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020438 (hypercalciuria)
 2,502 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
parathyroid hormone 356
Sep 146
PTH 135
alkaline phosphatase 90
calcium-sensing receptor 64
X-linked 61
proximal tubule 59
CLCN5 54
AMP 47
insulin 46
Claudin-16 46
GFR 44
vitamin D receptor 43
chloride channel 42
parathormone 41
calcitonin 41
osteocalcin 39
renin 37
Mol 37
albumin 34
TRPV5 34
chronic renal failure 32
collecting duct 30
ClC-5 29
gut 29
She 29
ATPase 29
NKCC2 28
SLC34A3 27
calbindin 24
CLC-5 24
Pol 23
CYP24A1 23
X-linked recessive 22
growth hormone 21
ROMK 19
CLDN19 18
FGF23 18
claudin-19 17
brush border 16
collagen 16
Parathyroid hormone 14
CaSR 14
parathyroid hormone-related protein 13
CLC 13
TRPV6 13
SLC34A1 12
cytokine 11
vasopressin 11
WNK4 10
OCRL1 10
FHH 10
claudin 16 10
prolactin 9
BMD 9
OCRL 9
KCNJ1 9
megalin 9
SLC12A3 8
G protein-coupled receptor 8
SLC12A1 8
claudin-14 8
PHEX 8
ClC-2 8
Mal 8
RTA 8
calcium sensing receptor 8
IGF-1 8
osteopontin 8
Net 8
aquaporin 7
ATP 7
ATP6V1B1 7
N-acetyl-beta-D-glucosaminidase 7
barttin 7
Calcitonin 7
TRPM6 7
casein 6
bone) 6
VDR mRNA 6
LCD 6
calcium channel 6
carbonic anhydrase 6
cubilin 6
CLCNKB 6
HEK 6
SPAK 5
osteogenic 5
beta 2-microglobulin 5
ash 5
uromodulin 5
CO2 5
Klotho 5
atrial natriuretic peptide 5
transferrin 5
G-protein-coupled receptor 5
Walker 5
insulin-like growth factor 5
aquaporin 2 5
VDR 5
glucagon 5
lactate dehydrogenase 5
NCX1 5
phosphatase 5
TAL 5
IGF-I 5
Alkaline phosphatase 5
AE1 4
type I collagen 4
FK506 4
klotho 4
dentin matrix protein 1 4
peroxidase 4
Nei 4
ACTH 4
osteosarcoma 4
UTI 4
MRI 4
ALP 4
BGP 4
Growth hormone 4
hemoglobin 4
ATP6V0A4 4
NHE3 4
MIM 4
endoplasmic reticulum 4
acid phosphatase 4
WNK1 4
lysozyme 4
SLC4A1 4
JAMA 4
period 2 4
reserved 4
CLDN10 3
pseudoxanthoma elasticum 3
membrane protein 3
IL-6 3
VDDR 3
calcium-binding protein 3
solute carrier 3
PKA 3
transient receptor potential melastatin 6 3
lectin 3
NCCT 3
Polymerase 3
ERK 3
CD4 3
thyroid hormone 3
matrix protein 3
CTX 3
CYP27B1 3
member 1 3
adenylate cyclase 3
glycoprotein 3
bumetanide-sensitive Na-K-2Cl cotransporter 3
lipopolysaccharide 3
epithelial calcium channel 3
calcineurin inhibitor 3
dihydropyrimidine dehydrogenase 3
NKCC1 3
more...
Disease
hypercalciuria 2502
hypercalcemia 465
nephrocalcinosis 439
nephrolithiasis 409
urolithiasis 275
hyperparathyroidism 187
hyperoxaluria 184
osteoporosis 172
primary hyperparathyroidism 172
rickets 150
proteinuria 147
renal tubular acidosis 122
renal failure 112
Bartter's syndrome 107
hypoparathyroidism 99
hypertension 93
sarcoidosis 92
wasting 92
osteomalacia 73
renal disease 68
diabetes 67
Dent's disease 67
urinary tract infection 64
bone disease 60
metabolic alkalosis 57
Idiopathic hypercalciuria 48
cystinuria 47
renal insufficiency 45
Fanconi syndrome 43
Fanconi 42
chronic renal failure 42
adenoma 41
cancer 41
tumor 37
failure to thrive 34
phosphaturia 33
vitamin D deficiency 31
Gitelman syndrome 29
dehydration 27
sponge kidney 27
hyperphosphatemia 27
hyperuricemia 26
malabsorption 25
aldosteronism 25
obesity 23
aminoaciduria 22
SEM 21
hyperthyroidism 21
primary hyperoxaluria 20
Lowe syndrome 20
metabolic disorder 20
renal impairment 18
tetany 16
HYP 16
hypogonadism 16
nephrogenic diabetes insipidus 15
glomerulosclerosis 14
deafness 14
hypokalemic alkalosis 14
Best 14
nephrotic syndrome 13
hypophosphaturia 13
thalassemia 13
tuberculosis 13
glomerulonephritis 13
ureter 13
carcinoma 13
calcinosis 13
alkalosis 12
plaque 12
magnesium deficiency 12
genetic disorder 11
Distal renal tubular acidosis 11
depression 11
uricosuria 11
acute renal failure 11
psoriasis 11
azotemia 10
hypervitaminosis 10
arthritis 10
hyperglycemia 10
hypothyroidism 10
myopia 10
hypermagnesemia 10
hydronephrosis 10
OHD 10
acromegaly 10
multiple myeloma 9
BMD 9
rare disease 9
SLC34A3, 9
epilepsy 9
hypophosphatasia 9
PDB 9
nystagmus 9
microalbuminuria 9
malnutrition 9
lymphadenopathy 9
diabetes insipidus 9
essential hypertension 9
West 8
type 2 diabetes 8
dysplasia 8
lymphoma 8
Parathyroid 8
anemia 8
Proteus 7
interstitial nephritis 7
prematurity 7
multiple endocrine neoplasia 7
mental retardation 7
mental retardation 7
diabetic nephropathy 7
lung disease 7
hyperinsulinemia 7
metastases 7
IgA nephropathy 7
pyuria 7
pyelonephritis 7
erythema nodosum 7
hyperchloremia 7
Cushing's syndrome 7
heart failure 7
fits 6
LCD 6
recurrent urinary tract infection 6
cystinosis 6
chronic renal insufficiency 6
uropathy 6
thyrotoxicosis 6
osteogenesis imperfecta 6
hypochloremia 6
Conn 5
pseudohypoparathyroidism 5
Alport syndrome 5
parathyroid hyperplasia 5
systemic disease 5
nephritis 5
respiratory failure 5
polycystic kidney 5
Williams syndrome 5
renal glycosuria 5
ash 5
osteosarcoma 5
Burnett 5
type 1 diabetes 5
hyperlipidemia 5
hypercortisolism 5
incontinence 5
acute lymphoblastic leukemia 5
developmental delay 5
stroke 5
breast cancer 5
chronic disease 5
ventricular hypertrophy 5
HHRH 5
demineralization of bone 4
WT1 4
rheumatoid arthritis 4
sensorineural hearing loss 4
more...
Symptom
polyuria 87
pain 35
polydipsia 29
abdominal pain 27
vomiting 26
bone pain 22
weakness 22
seizures 21
dysuria 17
diarrhea 17
renal colic 16
enuresis 14
flank pain 12
splenomegaly 8
fatigue 8
overweight 7
back pain 7
acidity 7
dyspnea 7
nausea 6
cough 5
myalgia 5
anorexia 5
hepatomegaly 4
hepatosplenomegaly 4
colic 4
constipation 4
bedwetting 3
agitation 3
hypotonia 3
urinary frequency 3
leg pain 2
hypercapnia 2
lethargy 2
muscle cramps 2
decreased appetite 2
carpopedal spasm 2
discomfort 2
collapse 2
thinning 2
paresthesia 2
arthralgia 2
ataxia 2
tremor 2
oliguria 2
pallor 2
headache 2
discomfort 2
abnormal gait 1
dizziness 1
sleepiness 1
vaginal itching 1
livedo 1
urethralgia 1
hyperemesis gravidarum 1
vertigo 1
generalized abdominal pain 1
productive cough 1
cachexia 1
Ill 1
cyanosis 1
Extrapyramidal symptoms 1
nocturnal polyuria 1
fever of unknown origin 1
skin irritation 1
rhinorrhea 1
functional recovery 1
Acute urinary retention 1
tachypnea 1
hemiplegia 1
syncope 1
phosphatemia 1
chest pain 1
sneezing 1
shortness of breath 1
asthenia 1
abdominal discomfort 1
knee pain 1
arm pain 1
apathy 1
anesthesia 1
chronic back pain 1
numbness 1
starvation 1
sore throat 1
stomach pain 1
Drug
PTH 137
Nephron 41
Nephron 41
Dial 19
Hydrochlorothiazide 12
Dermatol 9
Potassium citrate 8
Indomethacin 7
Cinacalcet 6
caffeine 6
lactose 5
citric acid 5
Growth hormone 4
ascorbate 4
Growth hormone 4
Gel 3
Prednisone 3
CaCl2 3
CTX 3
DMSA 3
Chlorothiazide 3
CaCl2 3
CTX 3
vitamin E 3
CTX 3
CaCl2 3
Clodronate 2
Vitamin B 2
ROC 2
Amiloride 2
Bendrofluazide 2
NAG 2
CSF 2
DDAVP 2
Amiloride 2
Ketoconazole 2
lysine 2
EHDP 2
Cardiovasc 2
Glucagon 2
Alfacalcidol 2
Metolazone 2
Tacalcitol 2
Teriparatide 2
DDAVP 2
APD 2
Lithostat 1
Pyridoxal phosphate 1
Sodium borate 1
Aredia 1
IL-11 1
Talc 1
Tiopronin 1
Deferasirox 1
TAC 1
Angiotensin II 1
Rocaltrol 1
Deflazacort 1
DHT 1
Fraction 1
Benazepril hydrochloride 1
Bonefos 1
Glutathione 1
pyridoxal phosphate 1
Auranofin 1
Lotrel 1
MRC 1
FLP 1
Calcibind 1
Prednisolone 1
Zoledronic acid 1
Vitamin K 1
Uralyt 1
Ergosterol 1
Ethane 1
Theophylline 1
Bumetanide 1
Lactose 1
Estrogens 1
Zmax 1
NADH 1
CTZ 1
Azithromycin 1
DHT 1
Ammonium chloride 1
Fluconazole 1
Carbetimer 1
CPM 1
Methylprednisolone 1
ADM 1
Zoledronic acid 1
Enzyme
alkaline phosphatase 90
renin 37
ATPase 29
ACE 14
prostaglandin synthetase 8
urease 8
urease 8
lactate dehydrogenase 7
carbonic anhydrase 6
1-hydroxylase 4
protein kinase C 4
ERK 4
peroxidase 4
lysozyme 4
reverse transcriptase 4
acid phosphatase 4
protein kinase 3
dihydropyrimidine dehydrogenase 3
phytase 3
adenylate cyclase 3
trypsin 3
luciferase 3
creatine kinase 3
phytase 3
mitogen-activated protein kinase 2
tissue kallikrein 2
AGT 2
endonuclease 2
calcineurin 2
CD10 2
gamma-glutamyl transpeptidase 2
cathepsin K 2
collagenase 2
plasmin 1
ADH 1
cytochrome oxidase 1
oxalate decarboxylase 1
thromboplastin 1
aspartate aminotransferase 1
PAH 1
transcriptase 1
alcohol dehydrogenase 1
sucrase 1
sucrase-isomaltase 1
PRA 1
ceruloplasmin 1
caspase-3 1
pyruvate dehydrogenase 1
RNA polymerase 1
kallikrein 1
retinoid isomerase 1
prolidase 1
fumarylacetoacetate hydrolase 1
lactase 1
caspase-9 1
NADPH oxidase 1
cysteine synthase 1
thrombin 1
calcium pump 1
asparaginase 1
nucleotide pyrophosphatase 1
glutathione peroxidase 1
focal adhesion kinase 1
CPM 1
citrate lyase 1
catalase 1
arachidonate 5-lipoxygenase 1
heparinase 1
glycerol kinase 1
pyruvate dehydrogenase 1
diacylglycerol kinase 1
biotinidase 1
HK2 1
glutathione reductase 1
NADPH oxidase 1
glutathione synthetase 1
alanine aminotransferase 1
phosphodiesterase 1
pyruvate dehydrogenase 1
5-oxoprolinase 1
DNA polymerase 1
N-acetyltransferase 1
xanthine oxidase 1
invertase 1
lipoxygenase 1
glucose-6-phosphate dehydrogenase 1
Compound
calcium 1660
phosphate 477
vitamin D 349
sodium 341
oxalate 327
Clin 289
creatinine 284
phosphorus 203
potassium 173
Dec 172
salt 94
water 90
cAMP 53
ammonium 53
AMP 46
aldosterone 42
glucose 39
Vitamin D 38
25-dihydroxycholecalciferol 37
DNA 36
carbonate 31
Mg2+ 28
urea 28
sodium chloride 26
Thiazide 25
sulfate 22
His 22
oxalic acid 21
hydrogen 20
Dial 19
nitrogen 18
phosphoric acid 17
Hydrochlorothiazide 13
Sodium 13
Salix 13
oxalic acid 12
oxalic acid 12
oxalic acid 12
ammonia 12
oxalic acid 12
oxalic acid 12
oxalic acid 12
oxalic acid 12
oxalic acid 12
oxalic acid 12
oxalic acid 12
oxalic acid 12
oxalic acid 12
Uric acid 12
oxalic acid 12
oxalic acid 12
oxalic acid 12
oxalic acid 12
aluminum 11
Vitamin D3 11
Vitamin D3 10
iron 10
PGE2 10
BMD 9
ethanol 9
hydroxide 9
CIT 9
arginine 9
PEG 9
HCO 9
PEG 9
CO2 8
proline 8
zinc 7
Insulin 7
ATP 7
acetate 7
Indomethacin 7
Calcitonin 7
copper 6
caffeine 6
Dexamethasone 6
oxygen 6
cadmium 6
25-hydroxycholecalciferol 5
alanine 5
Salt 4
cysteine 4
strontium 4
leucine 4
serine 4
ACTH 4
Estrogen 4
FK506 4
ALP 4
glutamate 4
lysine 4
Estrogen 4
HPP 4
galactose 3
Optimal 3
Prostaglandin 3
Cyclosporine 3
Prostaglandin 3
tryptophan 3
Cellulose 3
Chloroquine 3
CTX 3
Paricalcitol 3
methionine 3
Prednisone 3
6-12 3
tyrosine 3
Chloroquine 3
NCD 3
CaCl2 3
NH2 2
HCl 2
Pamidronate 2
Topiramate 2
PGE 2
Cystine 2
HPT 2
Parenteral 2
DOCA 2
Glucagon 2
ASA 2
TMP 2
PSP 2
TMP 2
Amiloride 2
chlorine 2
fluorine 2
PPi 2
Succinimide 2
EDTA 2
SDS 2
Angiotensin II 2
AHA 2
Octreotide 2
TMP 2
Ketoconazole 2
Lithium 2
TXA2 2
Hematoxylin 2
Pyridoxine 2
Alendronate 2
EDTA 2
glutamine 2
GAL 2
DMT 2
prostacyclin 2
TOF 2
Chlorthalidone 2
nitric oxide 2
Cystine 2
2-hydroxyethyl 2
Mithramycin 2
TMP 2
TPA 2
Alendronate 2
Gentamicin 2
5-oxoproline 1
Ceftriaxone 1
SP-1 1
more...