Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019829 (Hodgkin's disease)
 30,247 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Diagnostic usefulness of BAL was assessed in 25 selected cases of interstitial lung diseases. There were 14 cases of allergic alveolitis, 6 cases of idiopathic pulmonary fibrosis and one case each of sarcoidosis, lymphangiomyomatosis, granulomotosis bronchocentrica, lymphogranulomatosis maligna, alveolitis of unknown etiology. BAL was assessed diagnostically usefull in 77% of the cases. More helpful was medical history which proved to be useful in all cases, and pulmonary function tests which were helpful in 84%. Lung biopsy was diagnostic in 66.6% of the cases, TBLB in 36.5%, while open lung biopsy carried out in 6 patients was diagnostic in 100%. Bronchoalveolar lavage is a useful element of diagnostic evaluation in patients with interstitial lung disorders, it is a safe method and well tolerated by the patients.
Pneumonol Pol 1989 Feb
PMID:[Preliminary evaluation of the diagnostic usefulness of bronchoalveolar lavage (BAL) in selected cases of interstitial lung diseases]. 258 2

In 125 patients with non-Hodgkin lymphomas of low or medium malignancy the type of lymphoma determined on the basis of morphological features and immunological phenotype of lymphoma cells in then circulation was verified by histological examination of lymph node. Dissemination of lymphoma cells into blood was found to have occurred in 80% of patients. The highest agreement of histological and haematoimmunological diagnoses was found in lymphocytic lymphoma and lymphoplasmoid (immunocyte) lymphoma, and the lowest one was in centrocytic and centroblastic-centrocytic lymphoma. It is stressed that in a part of the patients histological examination of the lymph node could be abandoned.
Acta Haematol Pol
PMID:[Verification of hematological studies and immunologic phenotype of lymphoma cells in the blood by histological examination of the lymph nodes in non-Hodgkin's lymphoma of low and medium degree of malignancy]. 261 69

531 cases of malignant neoplasms and potentially malignant hyperplasia in children and adolescents diagnosed in the Department of Pathomorphology, Institute of Mother and Child between 1978/79 and 1983 are presented. Only patients treated in this hospital were included into the study. The most common diagnoses were neuroblastoma (68 cases), rhabdomyosarcoma (62 cases), nephroblastoma (56 cases), osteogenic sarcoma (47 cases), non-Hodgkin lymphoma (41 cases). Besides neoplasms most typical for childhood and adolescence the rare less typical cases were also seen.
Pediatr Pol 1989 Jun
PMID:[Malignant neoplasms and potentially malignant hyperplasia in children and adolescents from material at the Department of Pathomorphology, Institute of Mother and Child during 1978/79-1983]. 263 66

Radiotherapy was given to 32 patients with Hodgkin's disease (clinical stage IIA-IIIA) in whom chemotherapy given as the first treatment produced partial remission or minimal regression with disappearance of all systemic symptoms (27 cases) or recurrence developed after earlier treatment with cytostatic agents (5 cases). For a more accurate determination of the extent of lesions before radiotherapy in 24 cases laparotomy was done with splenectomy. Radiotherapy given in place of a second course of chemotherapy led in 24 cases (75%) to complete remission lasting from 8 to 62 months, mean 23.2 months. Twenty-one patients are still in continuing remission. These results point to the usefulness of considering the possibility of using radiation energy for the treatment of patients with advanced Hodgkin's disease (phase IIP-IIIP) in whom cytostatic drugs given as a first-line therapy failed to produce complete remission after 4-6 treatment courses, but caused some regression of symptoms with disappearance of systemic signs.
Acta Haematol Pol
PMID:[Radiotherapy instead of second-line chemotherapy in patients with Hodgkin's disease in partial remission after treatment with cytostatics]. 263 36

There are only few reports in the literature on the occurrence of hypothermia after chemotherapy. It occurred after various cytostatics and lasted for few hours to several days. Our material consisted of 11 patients with malignant lymphoma who were given chemotherapy protocols including cisplatin. In 5 patients (2 with Hodgkin's disease and 3 with non-Hodgkin's lymphoma) who had high fever, after treatment the temperature decreased down to 34.3 degrees C. Hypothermia disappeared spontaneously after few days. The drug responsible for this effect in our patients was cisplatin.
Pol Arch Med Wewn 1995 Feb
PMID:[Hypothermia during chemotherapy for lymphomas]. 747 30

Four cases of extraintestinal salmonellosis caused by Salmonella enteritidis were described. Underlying diseases in the three patients were haematological neoplasms (2 splenectomized and 1 with massive leukemic infiltrations of the spleen) and in the fourth haemophilia B: only that patient had a prior symptomatic intestinal infection. Blood cultures for S.ent. were positive in all patients and additionally in that suffering from Hodgkin's disease urine, lymph node and stool cultures also showed S.ent. In the haemophiliac patient culture of suppurated hematoma was positive. All patients recovered from S. sepsis but three then died of their neoplastic diseases. The haemophiliac patient is in a good condition. Various disturbances in the immunological tests were observed.
Pol Arch Med Wewn 1995 Feb
PMID:[Extraintestinal salmonellosis in patients with blood diseases caused by Salmonella enteritidis]. 747 35

28 patients suffering from advanced Hodgkin's disease were treated according to protocol containing 7 cytostatic drugs including methotrexate and corticosteroids, but not cyclophosphamide, chlormethine or procarbazine. 22 patients i.e. 78.5% attained complete remission and 5 i.e. 17.8% a partial one. Drug tolerance was satisfactory: out of side-effects the most common was myelosuppression, especially granulocytopenia. Our early results were similar to those obtained with MOPP-like protocols, but early undesirable effects less often and of a smaller degree. Because the protocol has been aimed at avoiding late toxicity of cytostatics, its final evaluation will be possible in the future.
Pol Arch Med Wewn 1995 Mar
PMID:[Evaluation of early treatment results in Hodgkin's disease during the cytostatic protocol containing methotrexate]. 747 44

Glomerular lesions have been reported to occur in association with a wide variety of malignancies, particularly carcinomas and lymphomas. Patients with the neoplastic diseases are exposed to continuous antigenemia, which stimulates antibody production and forms circulating immune complexes. Membranous nephropathy appears to be the most common glomerular lesion in patients with solid tumors, and minimal change glomerulopathy is another major form of glomerular disease associated with lymphomas, particularly with Hodgkin's disease. Three cases of nephropathy associated with anaplastic oat cell bronchial carcinoma, gastric adenocarcinoma and Hodgkin's disease were studied histologically, ultrastructurally and by immunofluorescence. The diagnosis of glomerulopathy preceded the diagnosis of malignant disease. All three patients were admitted to hospital because of nephrotic syndrome. The paraneoplastic glomerulopathies were histologically identical to that of idiopathic membranous glomerulonephritis and minimal change glomerulonephritis. Adult patients over the age of 50-60 with nephrotic syndrome caused by glomerulonephritis, especially by membranous nephropathy, should be screened for cancer.
Pol J Pathol 1995
PMID:Glomerulonephritis associated with malignant diseases of non-renal origin. A report of three cases and a review of the literature. 749 41

Twenty nine patients (7 women, 22 men) with III and IV stage of Hodgkin's disease were treated according to alternating programme ChLVPP/ABV. The results were evaluated in 27 patients. Complete remission was obtained in 41% (11 patients), partial remission in 22% (6 patients). Applied treatment revealed a relatively small toxicity.
Acta Haematol Pol 1994
PMID:[Treatment outcome of advanced Hodgkin's disease based on using an alternating program ChLVPP (chlorambucil, vinblastine, procarbazine, prednisone) and ABV (doxorubicin, bleomycin, vinblastine)]. 753 81

In a group of patients with non-Hodgkin lymphoma axonal sensorimotor polyneuropathy was found in 15%. It appeared in the treated patients, those receiving doses of oncovin. Polyneuropathy was not correlated with the type of malignancy. Treatment seems to be the important factor which can cause polyneuropathy.
Neurol Neurochir Pol
PMID:[Polyneuropathy in non-Hodgkin lymphoma]. 756 9


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