Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019829 (Hodgkin's disease)
 30,247 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 83-year-old woman was admitted because of pretibial edema. Echocardiography demonstrated a huge tumor in the right atrium and ventricle. Transvenous biopsy failed to obtain sufficient specimens for the histological diagnosis. The tumor progressed rapidly and heart failure was intractable. The diagnosis was primary cardiac lymphoma on the basis of elevated soluble interleukin-2 receptor and solitary accumulation of gallium-67 in the heart. Chemotherapy was immediately started. After two courses of chemotherapy, the intracardiac tumor disappeared. However, one month later, the tumor relapsed in the anterior mediastinum. Needle biopsy disclosed diffuse B-cell non-Hodgkin's malignant lymphoma. Additional irradiation reduced the tumor. Early diagnosis and immediate chemotherapy are important for the treatment of primary cardiac lymphoma.
J Cardiol 2002 Nov
PMID:[Primary cardiac lymphoma: a case report]. 1246 97

Primary malignant cardiac tumors, particularly lymphoma, are rare entities. Cardiac involvement or metastization of the heart from neoplasia located elsewhere are more frequently found. We present the case of a 79-year-old patient admitted with heart failure symptoms with a 3-week evolution. Evaluation led to the identification of a cardiac tumor with unusual clinical presentation and with a rapid and fatal evolution. Pathologic analysis identified a B-cell non-Hodgkin lymphoma.
Rev Port Cardiol 2003 Nov
PMID:Lymphoma with clinical presentation of a primary pericardial tumor. 1476 93

We present the case of a 36-year-old female with severe heart failure which developed 20 years after irradiation due to Hodgkin's disease.
Int J Cardiol 2004 Feb
PMID:Diastolic heart failure in female patient 20 years after radiotherapy due to Hodgkin's disease-a case report. 1497 68

We report the case of a 15-year-old male developing progressive myocardiopathy secondary to late anthracycline cardiotoxicity. At 2 years of age, the patient received chemotherapy with anthracyclines (adriamycin) at an accumulated dose of 510 mg/m2 due to the presence of non-Hodgkin lymphoma which subsided completely and he has been asymptomatic since then. A number of recurrent respiratory infections occurred as triggering factors of the condition, and the laboratory tests evidenced positive serology for Mycoplasma pneumoniae suggesting a recent contact.
Int J Cardiol 2005 Mar 18
PMID:Late anthracyclines cardiotoxicity associated with infection by Mycoplasma pneumoniae. A case report. 1574 4

Radiation therapy is the current standard therapy for several malignant disorders, including Hodgkin's disease. Cardiac complications, pericardial disease in particular, may develop long after the treatment. However, conduction disorders have rarely been described. We report a patient with the Wolff-Parkinson-White syndrome who developed complete heart block 16 years after mediastinal radiation therapy.
Int J Cardiol 2005 Sep 15
PMID:Complete heart block after mediastinal irradiation in a patient with the Wolff-Parkinson-White syndrome. 1613 21

A 27-year-old pregnant woman was admitted with supraventricular tachycardia (SVT) and symptoms of heart failure. Echocardiography revealed pulmonary hypertension due to a tumour infiltrating the left atrium and compressing the pulmonary veins. After delivery by Caesarean section, the paroxysmal SVT was controlled by amiodarone. Thoracic CT scan showed mediastinal masses compressing the pulmonary arteries and veins, and a preliminary diagnosis of Hodgkin's disease was later confirmed by mediastinoscopy and lymph node biopsy. Following two courses of chemotherapy the masses diminished. The lumen of the left atrium increased, pulmonary hypertension and SVTs receded.
Acta Cardiol 2005 Dec
PMID:Supraventricular tachycardia and pulmonary hypertension at the presentation of Hodgkin's disease. 1638 29

Mediastinal irradiation is a known cause of late onset cardiac complications including coronary artery disease. We describe a 58-year-old female patient, without any of the traditional coronary risk factors, who presented with inferior infarction 23 years after radiotherapy for Hodgkin's lymphoma of the mediastinum. Coronary angiography demonstrated severe ostial stenoses of both coronary arteries. The patient underwent coronary artery bypass grafting and is doing well 10 months later. The therapeutic value of mediastinal irradiation is unquestionable. However, it may be associated with late complications from the irradiated tissues, including the heart. Long-term follow up of cancer survivors who have received mediastinal irradiation should therefore include annual cardiac ultrasound examinations, as well as functional testing for the detection of myocardial ischaemia.
Hellenic J Cardiol
PMID:Coronary artery disease following mediastinal irradiation. 1762 83

We present a case of nearly total posterior mitral leaflet destruction due to Loeffler endocarditis associated with Hodgkin's lymphoma in a 15-year-old adolescent. The patient was treated medically with subsequent surgical mitral valve replacement. Cardiac aspects of hypereosinophilic syndrome are also discussed.
Pediatr Cardiol 2008 Sep
PMID:Mitral valve destruction by Hodgkin's lymphoma-associated Loefler endocarditis. 1800 15

A 74-year-old man presented for shortness of breath. Echocardiography revealed the presence of a large pericardial effusion with signs of tamponade. A right atrial mass was suspected and later confirmed by transesophageal echocardiography. The mass was attached to the right side of the interatrial septum. Surgical resection was performed. Histology was compatible with a diagnosis of undifferentiated B-cell non-Hodgkin's (Burkittlike) primary cardiac lymphoma. The present report provides the first description of a Burkitt-like primary cardiac lymphoma. The presence of a mass in the right atria should raise the possibility of a malignant cardiac tumour. Transesophageal echocardiography should be considered as the initial diagnostic procedure to be performed. Rapid histological diagnosis is important because systemic therapy can influence prognosis in the presence of a primary cardiac lymphoma.
Can J Cardiol 2009 Mar
PMID:Primary cardiac Burkitt-like lymphoma of the right atrium. 1927 85

A 53-year-old man, who had been treated for penile origin diffuse large B cell type non-Hodgkin lymphoma (NHL), suffered from right femoral pain and dyspnea. Positron emission tomography (PET) revealed abnormal accumulation in his right femur and cardiac segments. Transthoracic echocardiography revealed massive localized pericardial effusion with the collapse of both ventricles and the mass-like echo in the left atrium. We performed emergent pericardiocentesis and diagnosed this case as a recurrence of NHL with cardiac metastasis. With the use of transesophageal echocardiography (TEE), we confirmed the mass-like echo around the inter-atrial septum, which directly invaded to the aortic ring and the right atrial wall. In order to evaluate the effect of chemotherapy, we performed TEE and observed the precise changes of intra-cardiac tumor size. With the use of TEE monitoring, we could select the appropriate chemotherapeutic regimen, and the tumor became smaller and finally diminished. The femoral accumulation detected by PET also disappeared. We experienced a case of cardiac metastasis of NHL complicated with left ventricular diastolic collapse due to the massive localized pericardial effusion. TEE is a useful tool to evaluate precisely the efficacy of chemotherapy for intra-cardiac tumors.
J Cardiol 2009 Jun
PMID:Usefulness of transesophageal echocardiographic observation during chemotherapy for cardiac metastasis of non-Hodgkin lymphoma complicated with left ventricular diastolic collapse. 1947 89


<< Previous 1 2 3 4 5 6 7 Next >>