Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019829 (
Hodgkin's disease
)
30,247
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The effects of different kinds of anesthesia on the function of live (evaluated on the basis of activity of enzymes -- aspartate aminotransferase, fructose-I-monophosphate aldelase and
glutamate dehydrogenase
) were studied in 63 infantile patients with
Hodgkin's disease
who underwent diagnostic laparotomy with splenectomy. It was found that during the first 6 days after surgery, the rate of activity of these enzymes shows a rise and reaches the upper limits in 77.8% of cases. Halothane anesthesia induced excessive enzymatic activity in 100%, while neuroleptanalgesia -- in 53.8% of cases. Repeated application of halothane produced a higher hepatotoxic effect as manifested by enhanced activity of
glutamate dehydrogenase
on days 1--2 after operation.
...
PMID:[Effect of fluorothane anesthesia on liver function in children suffering from lymphogranulomatosis]. 724 73
