Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019829 (
Hodgkin's disease
)
30,247
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Treatment of
Hodgkin disease
(HD) with chemoradiotherapy in children is associated with increased risk for developing secondary neoplasms.
Parathyroid adenoma
(
PTA
) and chondrosarcoma (CS) are quite rare types of secondary neoplasms after HD. We describe a 5-year-old boy with stage IV HD, successfully treated with MOPP (mechlorethamine, vincristine, procarbazine, and prednisone)/ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) chemotherapy followed by 35 Gy mantle radiotherapy who developed primary hyperparathyroidism because of benign
PTA
at the age of 20 years, and died of CS in thoracic vertebrae at the age of 22 years. Consecutive occurrence of
PTA
and CS after treatment of pediatric HD, to the best of our knowledge, has not been reported earlier.
...
PMID:Parathyroid adenoma and chondrosarcoma after treatment of pediatric Hodgkin disease. 2073 43
