Gene/Protein
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Enzyme
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Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
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Target Concepts:
Gene/Protein
Disease
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Drug
Enzyme
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Query: UMLS:C0019693 (
HIV
)
170,526
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
This pilot study established that unlinked
anonymous
testing of dried blood spots routinely collected on Guthrie cards for neonatal screening is a feasible method for monitoring
HIV
prevalence in women at the time of delivery. The method was sensitive, specific, and less expensive than more conventional ELISAs. 114,515 dried blood spots taken from cards collected in three Thames regions were tested for antibody to
HIV
-1. 28 samples were confirmed to be antibody positive by western blot (seroprevalence 0.24 per 1000). Unlinked
anonymous
screening of newborn babies should be extended to monitor the spread of
HIV infection
in the heterosexual population and to target preventive strategies and provision of health care.
...
PMID:Prevalence of maternal HIV infection based on unlinked anonymous testing of newborn babies. 196 85
Using an
anonymous
questionnaire to obtain baseline data on sexual behaviour and knowledge of the acquired immunodeficiency syndrome (AIDS) among students in university residences, the following information was obtained: Knowledge of AIDS was found to be high, although misconceptions regarding transmission of the virus were prevalent. Mosquito bites (15%) and the donating of blood (31%) were incorrectly identified as methods of transmission of the virus. Deep kissing was recognised by only 27% of the students as a possible method of transmission while 22% and 13% of the students, respectively, failed to identify the sharing of razor blades and blood transfusions as possible means of contracting
HIV infection
. The students' knowledge had not greatly affected sexual behaviour. Two-thirds of the respondents had previously had sexual contact; 38% were sexually active at the time of the study, and of these 74% had engaged in unprotected intercourse with casual partners in the previous 6 months. There was a negative attitude towards condom use and over 80% of sexually active students did not perceive themselves to be at risk of contracting AIDS. Campus Health (82%), State health services (51%), and public advertisements (60%) were preferred sources of AIDS information. Newspapers/magazines (80%) and leaflets (69%) were identified as the preferred media. In reality, significantly fewer students obtained their information from Campus Health (15%; P less than 0.05), State health services (19%, P less than 0.05) and leaflets (44%; P less than 0.05). It can be concluded that education programmes should be developed by credible organisations to ensure that an awareness of AIDS results in appropriate sexual behaviour.
...
PMID:Perceptions and knowledge about the acquired immunodeficiency syndrome among students in university residences. 199 85
In a survey carried out in 1987 and 1988 in Vancouver British Columbia, 704 dental professionals filled out an
anonymous
questionnaire and submitted a blood sample. Of those not immunized, 11% had infection with Hepatitis B, with dentists having a rate of 18%, significantly higher than other dental workers. Two carriers of HBsAg were detected and no individuals showed evidence of
HIV infection
. There were no differences in infection rates by the specific infection control practices. Oriental dental-care workers had a significantly higher rate of infection than other races surveyed. In a multivariate model, race and the number of years in practice were the only significant factors in predicting infection. The use of gloves did not show a protective effect, although a threefold protection rate for gloves is the smallest difference that could be reliably detected. The immunization rate with Hepatitis B vaccine averaged 46%, with fewer dentists being immunized than hygienists. Seroconversion rates were lower in older individuals. Dental professionals had a high risk of Hepatitis B and had not been adequately immunized. Reliance on gloves for operator protection appears to be inadequate.
...
PMID:Hepatitis B and HIV infections in dental professionals: effectiveness of infection control procedures. 200 59
This study responds to a Centers for Disease Control request to develop innovative case-finding methods and asks two questions: 1) Will men participate in an
anonymous
telephone interview containing detailed questions about their sexual practices to enable screening for
HIV
-related risk? 2) Will individuals told they are at increased risk follow up by calling a toll-free number for additional AIDS information, counseling, or medical evaluation? Random-digit-dialed interviews were completed with 1610 adult men in Los Angeles County; the completion rate among eligible men was 68.3%. Nearly 43% of men were assessed at increased risk, half of whom described behaviors that placed them only at moderate risk and half of whom reported behaviors placing them at higher risk. Although the study found men were willing to provide personal risk-assessment information, only 14 of 343 men were willing to initiate a follow-up telephone call to the project counselors as the next step in case-finding.
...
PMID:Telephone screening for risk of HIV infection. 202 Feb 5
From September 1988 to August 1989, in a university hospital in Newark, NJ, 3529 serum and plasma specimens from patients with admitting conditions presumably not associated with human immunodeficiency virus (HIV) infection (Centers for Disease Control, Atlanta, Ga, Sentinel Hospital Surveillance System criteria) were tested anonymously for the presence of type 1 HIV (HIV-1) antibody. Of these specimens, 269 (7.6%) were confirmed HIV-1 seropositive. Overall, 10.3% of male patients and 4.8% of female patients were seropositive. Persons 25 to 44 years old had the highest HIV-1 seroprevalence- 20.9% for male and 7.5% for female patients. Based on this
anonymous
testing, the number of HIV-infected hospitalized patients discharged in 1988 was estimated. Data on hospital-confirmed HIV-infected patients tested on the basis of clinical suspicion suggest that only 40% of HIV-infected patients were actually tested for HIV-1 infection as part of their medical care in this hospital. These data demonstrate a high prevalence of
HIV infection
in this patient population and suggest that hospitals serving populations with a high HIV seroprevalence offer routine screening for
HIV infection
as part of good medical care.
...
PMID:Anonymous human immunodeficiency virus surveillance and clinically directed testing in a Newark, NJ, hospital. 202 45
At present, we can observe an evolution in ideas about the detection of
HIV
seropositivity through a qualitative analysis of specialised literature on the ethical aspects of AIDS. In the case of this disease, systematic screening of the population does not correspond to epidemiological criteria: it is wasteful, troublesome and costly. Whether it is voluntary, and therefore biased, or compulsory, and therefore controversial, systematic screening seems an unlikely option. This situation has prompted many versions of target-group screening, which correspond to two options: systematic screening of known risk-groups, discriminatory, confidential and
anonymous
; target-group screening linked to particular circumstances: recognised as necessary by blood-donors and well-accepted by pregnant mothers. This method can be institutionalised and applied in the armed forces and in prisons,.... Lastly, we consider measures taken by different countries and organisations.
...
PMID:AIDS, a social dilemma: detection of seropositives. 204 10
A questionnaire survey was held among 938 doctors and 2304 nurses to assess their attitudes toward AIDS and the influence of their concern about the occupational risks involved. The response was 65 and 72%, respectively. The results suggest that in treating patients with actual or possible
HIV infection
, in non-invasive procedures many doctors and nurses often take too many precautions, whereas in invasive procedures doctors often take too few. A minority of the respondents were in favour of testing all patients. The majority felt that patients in the high-risk groups should be tested. The percentage in favour of
anonymous
testing was considerably higher among the doctors than among the nurses. Most of the doctors and nurses were concerned about contagion by patients. This concern had a negative influence on their attitudes toward AIDS. Factual information alone does not suffice to dispel excessive concern. In training and educating medical personnel, attention should be devoted to cognitive as well as emotional aspects.
...
PMID:Attitudes of health-care workers towards AIDS at three Dutch hospitals. 205 61
Interviews that took place at several sites where
anonymous
sex is practiced suggest that some married men engage in same sex activity without regard for the risk to
HIV infection
they impose upon themselves and their spouses. Much of the sexual activity is considered to be high risk by Centers for Disease Control standards, and the men who engaged in these behaviors were knowledgeable of those standards. A random sample of 94 individuals were interviewed from a possible population of 198 (47.9%). Of the men interviewed, 15% identified themselves as married or engaged to be married to a woman. Only 2 married men informed their female sex partner (regular partner) of their clandestine activity. By comparison, 29 of the gay or bisexual men had informed their partners of their unprotected and
anonymous
sex seeking. It is suggested that perhaps the focus on high risk groups instead of on high risk behavior has given a false sense of security to men who do not identify as gay or bisexual.
...
PMID:Married men and same sex activity: a field study on HIV risk among men who do not identify as gay or bisexual. 207 7
This paper provides an early report of a continuing ethnographic study of male prostitution in Glasgow. Pilot work indicates that rent boy activity may be of considerable importance for the spread of
HIV infection
. Although there is little evidence of an association between rent boy activity and injecting drug use, rent boys may well be implicated in epidemic spread because many (but not all) of them report unsafe sexual practices. Some boys reported that they engaged in unprotected anal sex both actively (insertor) and passively (insertee). Although the majority of the boys' clients were covert bisexuals--married men seeking occasional,
anonymous
, male sexual contact--a substantial minority of clients were gay-identified.
...
PMID:An ethnographic study of HIV-related risk practices among Glasgow rent boys and their clients: report of a pilot study. 208 56
Considerable voluntary risk reduction has occurred among IVDUs in New York City. The purpose of the AIDS Outreach Project was to improve upon the existing level of risk reduction by providing information and
anonymous
HIV
testing to street-recruited IVDUs. Intake and follow-up interviews were conducted with 121 subjects (44% of 276 at intake), with a mean of 4.5 months between interviews. Significant risk reduction occurred in many drug and sexual risk behaviors, although not in bleach use, and more than half of the subjects continued to engage in high-risk sexual behavior. An analysis of differences in risk reduction between early and later intake groups indicated that external trends were not sufficient to account for observed risk reduction. Among subjects engaged in high-risk behavior at intake, those who injected less or were enrolled in drug abuse treatment were more likely to stop high-risk drug injecting. Subjects who (at intake) engaged in less frequent unprotected sex, or who had had sex with someone with AIDS, were more likely to stop high-risk sexual behavior. The majority of subjects at low risk at intake maintained low-risk behavior. Informational interventions appear to be most successful among those IVDUs already engaging in lower levels of risk behavior. More effective methods are needed for those whose level of risk behavior is greater. These might include peer pressure and distributing bleach (as opposed to only providing information about bleach).
...
PMID:Effects of outreach intervention on risk reduction among intravenous drug users. 209 57
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