Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
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Drug
Enzyme
Compound
Query: UMLS:C0019693 (
HIV
)
170,526
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Self-care was investigated in this grounded theory study of 22
HIV
-positive women incarcerated in a medium security prison in the southeastern United States. Findings revealed four phases in a social-psychological process of movement from neglect of health to self-care. Phases I and II revealed five social-psychological cofactors that constrained self-care and promoted vulnerability to poor physical and emotional health over time. Phase I, "Recurring Memories of
Abuse
," focused on the damage of abuse histories; Phase II, "Repeating Harmful Coping Behaviors," described maladaptive coping behaviors that put women at risk for
HIV infection
and incarceration; Phase III, "Searching for Self-Care," exposed the shock of incarceration and the
HIV
-positive diagnosis and symbolized a turning point in thinking about health and self-care. During Phase III, women discovered the possibility for better health through self-care. In Phase IV, "Connecting in Caring Relationships," women described their need for relationships that would help them promote and sustain self-care.
...
PMID:From neglect to care: a theory to guide HIV-positive incarcerated women in self-care. 1457 84
Methadone maintenance programs (MMP) have the potential to play an important role in reducing
HIV
risk, given the appropriate type and level of ancillary treatments. In this study, we investigated the efficacy of a 12-session harm reduction group intervention for injection drug users, based upon the Information-Motivation-Behavioral skills model of behavior change, that focused on reducing both drug and sex risk. Two hundred and twenty patients entering an MMP were randomized to receive either standard care (SC)-2 hours of counseling per month and a single-session risk reduction intervention-or SC plus the harm reduction group (HRG). Results showed that during treatment, patients receiving HRG were more likely to be abstinent from cocaine and to report fewer unsafe sexual practices. Post-treatment, HRG patients scored higher on a sexual risk quiz and reported increased self-efficacy in high risk sexual situations. Enhancing methadone maintenance with a weekly harm reduction group treatment was somewhat more expensive but can bring about positive changes in behaviors and attitudes that are associated with the transmission of
HIV
.
J Subst
Abuse
Treat 2004 Mar
PMID:Targeting HIV-related outcomes with intravenous drug users maintained on methadone: a randomized clinical trial of a harm reduction group therapy. 1505 83
Naltrexone may be more effective for treating opioid (heroin) dependence in Russia than in the U.S. because patients are mostly young and living with their parents, who can control medication compliance. In this pilot study we randomized 52 consenting patients who completed detoxification in St. Petersburg to a double blind, 6-month course of biweekly drug counseling and naltrexone, or counseling and placebo naltrexone. Significant differences in retention and relapse favoring naltrexone were seen beginning at 1 month and continuing throughout the study. At the end of 6 months, 12 of the 27 naltrexone patients (44.4%) remained in treatment and had not relapsed as compared to 4 of 25 placebo patients (16%; p<0.05). Since heroin dependence is the main way
HIV
is being spread in Russia, naltrexone is likely to improve treatment outcome and help reduce the spread of
HIV
if it can be made more widely available.
J Subst
Abuse
Treat 2004 Jun
PMID:Naltrexone for heroin dependence treatment in St. Petersburg, Russia. 1518 93
Many substance abuse treatment (SAT) facilities offer programs designed specifically for special populations such as women, adolescents, gays/lesbians and others. Previous research shows that there are specific services that are integral to the successful treatment of these populations (e.g., family therapy for adolescents, childcare and transportation assistance for women, and
HIV
testing and counseling for gays/lesbians). This study examines whether facilities that self-report having programs for special populations actually offer the recommended services. The data come from the 2000 National Survey of Substance Abuse Treatment Services, which contains information on service offerings, special programs and other characteristics for all SAT facilities in the USA. The results indicate that facilities with special programs are more likely to offer the recommended key services. However, often less than half of these facilities provide the key services. There are consistent differences by ownership status, with for-profit facilities less likely to offer many of the key services.
J Subst
Abuse
Treat 2004 Jul
PMID:To what extent are key services offered in treatment programs for special populations? 1522 88
This study examined the effectiveness of a combined counseling and case management behavioral intervention, using motivational interviewing strategies, in engaging Hispanic injection drug users in treatment and reducing drug use and injection-related
HIV
risk behaviors. Follow up data are presented on 440 (79.0%) of 557 randomized participants, 6 months after the initial interview. Subjects in the experimental arm were significantly less likely to continue drug injection independent of entering drug treatment, and were also more likely to enter drug treatment. Subjects in both arms who entered drug treatment were less likely to continue drug injection. Among subjects who continued drug injection, those in the experimental arm were significantly less likely to share needles. Confirming the outcomes of this study in other Hispanic sites and populations could be a critical step towards reducing factors that contribute to the self-sustaining
HIV
/AIDS epidemic in Puerto Rico and communities in the U.S. mainland.
J Subst
Abuse
Treat 2004 Sep
PMID:Effects of combined counseling and case management to reduce HIV risk behaviors among Hispanic drug injectors in Puerto Rico: a randomized controlled study. 1545 Jun 47
This study longitudinally examines the relation between a history of experiencing childhood and adult physical or sexual abuse, and male condom use by women with or at risk for
HIV
.
Abuse
history and prospective condom use data were collected from 214
HIV
infected and 189 uninfected women participating in the
HIV
Epidemiology Research Study (HERS) who were inconsistent condom users at baseline and received two safer sex counseling sessions. Analyses were conducted to assess the association between abuse history and condom use while controlling for sociodemographic variables and other risk factors.
HIV
-uninfected women with a history of adult physical abuse were five times less likely to report consistent condom use at 1-year follow-up than uninfected women without a history of abuse while holding control variables constant. Expectations of a negative reaction by the partner to suggested condom use did not explain this association. Though in the same direction as in uninfected women, abuse history was not significantly related to consistent condom use among
HIV
-infected women. These data indicate the need to develop risk prevention strategies tailored to uninfected women with a history of adult abuse. In lieu of specialized interventions, health care providers should assess women's abuse history and supplement
HIV
prevention counseling with mental health counseling when indicated.
...
PMID:Persistence of inconsistent condom use: relation to abuse history and HIV serostatus. 1547 80
We examined the association of substance abuse treatment with sexual and drug use risk behaviors among 349
HIV
-infected persons with a history of alcohol problems using a standardized questionnaire regarding sexual and drug use risk behaviors, demographics, substance use, and use of substance abuse treatment. We defined substance abuse treatment services as any of the following in the past 6 months: 12 weeks in a half-way house or residential facility; 12 visits to a substance abuse counselor or mental health professional; day treatment for at least 30 days; or participation in any methadone maintenance program. Our three outcome variables of high-risk behavior were the Risk Assessment Battery sex-risk and drug-risk scores and high-risk sex behavior which included any of the following: inconsistent condom use; having more than one sexual partner; and exchanging sex for money or drugs. Although sexual risk was high (51%) in our
HIV
-infected cohort, engagement in substance abuse treatment was not independently associated with lower frequency of any of our measures of high- risk behaviors. Although the opportunity exists to address
HIV
risk behaviors in the setting of substance abuse treatment, effective institutionalization of this challenging behavior change effort has not yet been realized.
J Subst
Abuse
Treat 2005 Jan
PMID:Substance abuse treatment and risk behaviors among HIV-infected persons with alcohol problems. 1572 26
Abuse
, sexual satisfaction, and sexual dysfunction are issues that are not readily addressed in the African-American population, but they are on the minds of many. Ebony decided to pose these and other questions to African-American women in a survey titled, "Are You Satisfied?" Respondents were subscribers to Ebony as well as newsstand readership. Participants either filled out the survey on the Ebony website or sent in a paper copy to be tabulated. African-American women (N=7800) from all walks of life responded and discussed their abuse histories, their relationships, their ability or inability to reach orgasm, their medical histories and level of comfort in discussing their problems with their physicians, as well as many other issues. Results indicate that 37% of the sample self-reported early sexual abuse at the hands of immediate and/or extended family members; 15%-18% have been treated for high blood pressure, STDs/
HIV
, and/or fibroids; and 33% have experienced an inability to achieve orgasm in the last year. Of the sample 47% stated that they had not discussed these problems with their physicians.
...
PMID:The Ebony Sex Survey and the sex lives of African-American women: a call to healthcare providers. 1582 37
Consecutive intakes (N = 419) between ages 13 and 18 years to chemical dependency (CD) programs in a large private health plan were interviewed. The prevalence of six
HIV
risk behaviors was measured and categorized into zero, one, and multiple risk groups. The relationships between both demographic characteristics and substance use with
HIV
risk behaviors were examined. Approximately half the sample reported at least one risk behavior, with 17% reporting multiple risk behaviors. Those most likely to report multiple risk behaviors were heavy drinking boys, as well as girls who reported using narcotic analgesics. Implications of these findings for pediatricians and CD clinicians are discussed.
J Subst
Abuse
Treat 2005 Jul
PMID:Adolescents in private chemical dependency programs: who are most at risk for HIV? 1597 30
The purpose of this study was to explore the relationship between methamphetamine (meth) use and impulsivity in a sample of 385
HIV
-negative heterosexually identified meth users. Participants who scored highest on a self-report measure of impulsivity were compared with those who scored lower in terms of background characteristics, meth use patterns, use of alcohol and other illicit drugs, sexual risk behavior, and psychiatric health variables. Methamphetamine users in the high impulsivity group were younger, less educated, used larger quantities of meth, were more likely to be binge users, had a larger number of sexual partners, engaged in more unprotected vaginal and oral sex, and scored higher on the Beck Depression Inventory as compared with those in the low impulsivity group. In a logistic regression analysis, Beck depression was the factor that best distinguished between meth users who scored high and those who scored low on impulsivity. Neurophysiological pathways that may underlie the relationship between impulsivity and meth use are discussed.
J Subst
Abuse
Treat 2005 Sep
PMID:Impulsivity and methamphetamine use. 1613 37
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