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Query: UMLS:C0019693 (HIV)
 170,526 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Persistent neutrophilic meningitis is rarely found and it is characterized by predominance of the number of neutrophils in samples of C SF (cerebrospinal fluid) from the patient after seven days of treatment. The above patient in HIV positive; he has developed fever and mental disorder for 4 months and has presented neutrophilic pleocytosis in analysis of CSF for more than 5 months. Since the beginning or the treatment he has taken antituberculous drugs and corticosteroids. For 3 months, the serologic evaluation, smears and cultures were negative. On the 60th day in hospital, the investigation of acid-fast bacilli in CSF was positive and culture confirmed the presence of Mycobacterium tuberculosis resistant to isoniazid. Several factors that may have caused this uncommon development were discussed: the disturbance of cell-mediated immunity, mainly in release of IL 8 and TNF, the simultaneous use of medicines that could alter the CSF concentration of antituberculous drugs, and the increasing number of multiresistant strains.
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PMID:[Persistent neutrophilic meningitis in a patient with the acquired immunodeficiency syndrome]. 927 71

People who suffer from mental disorders are at increased risk for becoming infected with HIV. There have been no studies that show whether particular psychiatric disorders present an increased risk for HIV infection in samples of nonpatients. This article uses data from the 1992 National Survey of Veterans to determine if veterans with posttraumatic stress disorder (PTSD), or with other mental or emotional problems, are at increased risk for HIV infection. The results indicate that the combination of PTSD and substance abuse increased the risk of HIV infection by almost 12 times over those without either. This is evidence of a particular psychiatric disorder increasing risk for HIV. Although cross-sectional, these data allow some conjecture about the timing of the onset of PTSD in relation to HIV infection. These results present powerful evidence that mentally ill persons such as those with PTSD, who may be underserved for health services including AIDS prevention efforts, should be targeted as an at-risk group.
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PMID:Mental disorder as a risk factor for human immunodeficiency virus infection in a sample of veterans. 930 17

A review of the literature indicates that women with schizophrenia may have limited knowledge about sexuality, high rates of coerced sex, low contraceptive usage, many unwanted pregnancies, and severe parenting difficulties. Given problems with contraceptive compliance, long-acting hormonal methods are optimal. Since schizophrenic women are especially vulnerable to exacerbations of mental illness during pregnancy, the risks to the mother of withholding pharmacotherapy must be weighed against the slight increase in risks of congenital anomalies associated with such treatment. Postpartum psychotic episodes are also common, with serious consequences for the mother-infant relationship. The quality of child care provided by mothers with schizophrenia may be compromised by a reduced ability to read children's cues and weak social support networks. Mental health services and child welfare agencies need to collaborate to weigh the risks to a child of remaining with a psychotic parent versus those of being removed from the home. Recommended for mental heath practice are the following: incorporation of sex education and assertiveness training into psychosocial rehabilitation programs, HIV education and screening, systems for the early detection of pregnancy in chronically mentally ill women, steps to reduce the likelihood of relapse during the vulnerable postpartum period, improved methods for assessing parenting capability, parenting education, and the incorporation of family planning programs into mental health care delivery systems.
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PMID:Sexuality, reproduction, and family planning in women with schizophrenia. 936 99

The AAHP investigated the neurobehavioral and psychosocial sequelae of HIV-1 and substance use in urban African American men. A community resident sample of 502 African American men stratified by HIV-1 serostatus, drug use and sexual orientation were recruited. A comprehensive battery of measures of neurobehavioral and health status, lifestyle and psychosocial characteristics were administered to all participants, and a stratified sub-sample of 120 participants were tested using state of the art brain imaging techniques to investigate differences in the functional and neurophysiologic effects of HIV-1 and substance use. An overview of the methodology of the AAHP and results on high risk sexual and substance use behaviors, and psychiatric disorders are presented and discussed. The sample was primarily HIV-negative (63%), heterosexual (49% gay or bisexual) and a high percentage used substances during the past year (56% used drugs and 30% moderate/heavy drinkers). High-risk sexual practices were relatively prevalent, and a high percentage reported a history of STDs and other infections. Finally, 25% had a current psychiatric disorder, with gays/bisexuals and HIV-seropositives evidencing greater psychiatric vulnerability. More research is needed to further explore the apparent greater risk for psychiatric disorders among gay and bisexual men, and to determine whether being African American and lower social class exacerbate this risk.
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PMID:The African-American Health Project (AAHP): study overview and select findings on high risk behaviors and psychiatric disorders in African American men. 942 83

This study attempts to identify the specific role that each of three conditions afflicting homeless, mentally ill, chemically misusing (HMICM) men plays in exposing these men to the risk of HIV infection. Three hundred and fifteen HMICM men (33 of whom were HIV+) were interviewed on intravenous drug use (IVDU) and sex practices. Two scales of risky IVDU practices and sex conducts were constructed and analyzed in relation to HIV status. The severity of homelessness, mental illness, and chemical misuse, then, were analyzed as possible predictors of risky IVDU and sex practices. Strong correlations were found between IVDU practices and HIV seropositivity, and between risky sex conduct and HIV seropositivity. Serious depression was the strongest predictor of risky IVDU practices. Prolonged homelessness was the condition most associated with risky sexual conduct. This study concludes that HMICM men are at high risk for HIV infection, stemming, predominately, from two conditions: depression, leading to risky IVDU practices, and homelessness, leading to risky sex conduct with two separate types of risky behavior.
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PMID:HIV infection risks among homeless, mentally ill, chemical misusing men. 960 78

We documented HIV-risk behavior and the public health context of AIDS in women living with a severe and persistent mental illness. Sixty-one women were recruited from outpatient clinics and day-treatment programs at a state psychiatric hospital. They completed a survey that included measures of HIV-related risk behavior, the perceived importance of 11 public health and social problems including AIDS, HIV/AIDS-related knowledge, perceived risk, and behavioral intentions. Thirty-eight percent of participants engaged in at least one type of HIV-risk behavior during the 2 months before assessment, 23% reported two or more risk factors, and 16% reported three or more risk factors. Consistent condom use was rare. Participants reporting 1 or more risk factors were more likely than those reporting no risk to report histories of alcohol or drug treatment, sexually transmitted diseases, HIV testing, and more perceived risk of HIV infection. Poverty and unemployment were viewed as more serious problems than HIV infection and AIDS. HIV-prevention interventions that are tailored to the needs and priorities of women with a severe mental illness are urgently needed to prevent further infections.
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PMID:HIV-risk behavior and the public health context of HIV/AIDS among women living with a severe and persistent mental illness. 961 44

The prevalence of individuals with or at risk for HIV infection in prisons and jails is severalfold higher than age-adjusted rates in surrounding communities. This HIV serosurvey of 975 newly sentenced male prisoners employed a new methodology that anonymously linked individual information to HIV serologic data. The HIV prevalence was 6.1%; multivariate regression analysis indicated injection drug use (OR = 18.9), black race (OR = 5.5), Hispanic ethnicity (OR = 3.4), psychiatric illness (OR = 3.1) and a history of having had a sexually transmitted disease (OR = 2.2) were independent predictors of HIV infection. Laboratory markers such as hypoalbuminemia, an elevated aspartate aminotransferase (AST) level, leukopenia, anemia, and thrombocytopenia suggest increased risk for HIV among prisoners, particularly in settings where HIV testing resources are scarce. This study, unlike those reported in other geographic regions, indicated that the majority (71%) of HIV-seropositive persons self-reported their HIV status. This finding may suggest that HIV-infected individuals will self-report their status if HIV care is comprehensive and consistent. The large number of HIV-infected individuals within prisons makes prisons important sites for the introduction of comprehensive HIV-related care. This is particularly relevant in that development of new guidelines issued for the management of HIV infection in which potent combination antiretroviral therapy has been demonstrated to decrease morbidity and mortality. The high prevalence of HIV-seronegative inmates with self-reported high-risk behaviors also suggests the importance of prisons as sites for the introduction of appropriate risk-reduction interventions.
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PMID:Predictors of HIV infection among newly sentenced male prisoners. 971 40

1. Safer-sex education is crucial for controlling the spread of HIV and this education is within the realm of nursing practice. 2. Safer-sex education for persons with mental illness must include repetitive, interactive education capitalizing on verbal, visual, written, tactile, and motor skill teaching methods to compensate for learning disabilities that have been identified in this population. 3. In this study, individual rather than a group teaching approach to the sensitive subject of safer-sex provided the most learning. The study subjects did not exhibit overt sexual behavior, increased sexual acting out, regression, or overstimulation when safer-sex education was presented.
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PMID:Safer-sex education for persons with mental illness. 972 84

This study examined whether training women living with a severe mental illness to be assertive in sexual situations would decrease their risk for HIV infection. Twenty female outpatients were randomly assigned to either a 10-session assertiveness training intervention or a waiting-list control condition. All participants completed measures of HIV-related information, motivation, skills, and sexual risk behavior pre- and postintervention and at 2- and 4-month follow-ups. Compared with controls, women in the intervention group increased their assertiveness skill, HIV knowledge, and frequency of condom-protected intercourse. It is concluded that assertiveness training for women living with a severe mental illness can serve as 1 part of a comprehensive HIV-risk-reduction program for this vulnerable population.
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PMID:Increasing assertiveness skills to reduce HIV risk among women living with a severe and persistent mental illness. 973 86

In this chapter we review research on the relationships between substance use disorder and 11 domains of adjustment for people with severe mental illness. Studies are divided into correlational research and prospective, longitudinal research, with greater weight given to those in the latter category. The weight of the evidence indicates that substance abuse severely complicates severe mental illness in the following domains: relapse of psychiatric illness, hospitalization, disruptive behavior, familial problems, residential instability, decreased functional status, HIV infection, and medication noncompliance. We discuss the limits of causal inference in these studies and the possible mechanisms that relate substance abuse to various complications.
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PMID:Complications of severe mental illness related to alcohol and drug use disorders. 975 50


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