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Query: UMLS:C0019693 (HIV)
 170,526 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

There is very little published information regarding the co-occurrence of human immunodeficiency virus (HIV)-spectrum illness and psychotic illnesses, including schizophrenia, even though their coexistence in the same patient may severely affect the course of both illnesses. Estimates of the frequency of HIV infection in patients with preexisting mental illness range between 5 and 7 percent. Estimates of new-onset psychosis in patients with HIV-spectrum illness range between 0.2 and 15 percent and may increase as the stage of HIV illness progresses. Regardless of which illness came first, their occurrence together appears to be associated with more morbidity and mortality than would be expected with either illness alone. Patients with new-onset psychosis respond to and tolerate relatively low doses of antipsychotic medication. Whether the presence of HIV decreases the effective daily dose of neuroleptic medication in patients with preexisting psychosis is not yet known. A clearly superior neuroleptic medication for patients with both psychosis and HIV infection has not yet been identified. Further systematic exploration is needed.
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PMID:Schizophrenia and HIV. 887 97

The epidemic of dually diagnosed patients with HIV disease (HIV disease coexisting with substance abuse and/or mental illness) has become increasingly recognized. This phenomenon poses potential threats to the effectiveness of HIV primary care, even when delivered by expert clinicians. This article describes implementation strategies for the provision, documentation, and third party billing of interdisciplinary, interagency HIV primary care case management within the context of an academic medical center. Our approach, which is specific to our setting, has evolved as we have attempted to define an active role for the primary care physician as a member of the case management team.
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PMID:An interdisciplinary, interagency, primary care approach to case management of the dually diagnosed patient with HIV disease. 890 37

Psychiatric patients, like any other medical patients, are vulnerable to HIV infection and those infected with HIV could transmit the virus to others. Some studies have found that the severely mentally ill as a group are more vulnerable to HIV infection because of comorbidity with substance abuse. Unsafe sexual behavior has also been reported among the severely mentally ill. Blood samples from 87 male and 56 female patients consecutively admitted to Harare Central Hospital's Psychiatric Unit were tested with ELISA and Western blot for infection with HIV. The subjects were 17-70 years old of mean age 32.5 years with a mean 4.21 years of psychiatric illness. 23.8% were infected with HIV and HIV infection was significantly related to high education attainment and being unemployed. Preventive interventions are urgently needed for HIV-infected psychiatric patients in Zimbabwe.
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PMID:Serostatus surveillance testing of HIV-I infection among Zimbabwean psychiatric inpatients, in Zimbabwe. 899 17

HIV-1 infection may be complicated by a number of psychopathological conditions. While organic mental disorders, such as HIV-related psychosis and dementia, are late manifestations, mood disorders may occur during both asymptomatic and symptomatic stages of infection. The possible impact of brain involvement due to neurotropism of HIV-1 has not been investigated systematically in these latter conditions. The psychiatric caseness of HIV-seropositive individuals without AIDS and seronegative controls was assessed using a standardized clinical interview (Present State Examination). A comparison was made between individuals with and without psychiatric caseness using clinical, neuropsychological, and neurophysiological assessments. An increased prevalence of current psychiatric illness was found in subjects with early symptomatic HIV infection compared to those with asymptomatic infection and controls. This could not be attributed to psychiatric history, as well as to clinical and immunological markers of HIV infection, however, psychiatric caseness in early symptomatic infection was associated with marked neurophysiological changes, detectable by quantitative electroencephalography. Altogether, this study provided preliminary evidence that psychiatric symptoms in symptomatic but not asymptomatic HIV infection may be associated with subtle brain involvement preceding the immunological and neurocognitive impairment characteristic for AIDS.
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PMID:Neurophysiological changes associated with psychiatric symptoms in HIV-infected individuals without AIDS. 903 42

This paper is based on the author's ethnographic HIV prevention research at a community-based residence for women in New York City who have a history of homelessness and diagnosis of mental illness. The author presents the human face of this American tragedy, while exploring the ways in which larger social forces circumscribe these women's lives. The author also critically assesses the HIV prevention agenda, including the dominant paradigm in prevention intervention. Despite acceptance by the most prominent players in AIDS prevention in the United States, the most popular prevention theories are theoretically and substantively inadequate. While educational interventions and behavior change efforts may have some impact on inhibiting HIV transmission, the focus on the individual as the sole locus of change tends to obscure the social and material factors in the spread of the disease. An anthropologically informed alternative, integrating social responsibility and social justice, is explored. Also considered are dilemmas in applying anthropology to AIDS prevention research and how to translate theoretical abstractions into humane and pragmatic social programs.
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PMID:Anthropological research and the politics of HIV prevention: towards a critique of policy and priorities in the age of AIDS. 914 Nov 70

Men and women who have a severe and persistent mental illness are vulnerable to infection with HIV. Recognition of this vulnerability led the Office of AIDS at the National Institute of Mental Health (NIMH) to invite leading practitioners, researchers, consumer advocates, and policy makers to a National Conference on HIV and AIDS among the Severely Mentally Ill. This article describes the proceedings of the Conference, and provides an overview of the resulting summary reports that comprise this special issue.
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PMID:HIV and AIDS among the severely mentally ill: introduction to the special series. 916 Jan 74

The authors reviewed all studies in the peer-reviewed literature reporting HIV seroprevalence among people with severe mental illness in the United States, which varied from 4.0% to 22.9%. Findings across samples suggest that seroprevalence varies with geographic concentration of HIV and presence of comorbid psychoactive substance use disorders, but is consistently high. Unsafe sex, drug injection, and noninjected drug use were associated with infection, and in most studies women were as likely to be infected as men. Seroprevalence also varied with age and ethnicity, but not psychiatric diagnosis. The authors review questions and methodological issues important to future studies.
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PMID:HIV seroprevalence among people with severe mental illness in the United States: a critical review. 916 Jan 76

Medical and neuropsychiatric sequelae of HIV infection present a spectrum of diagnostic and treatment challenges to mental health clinicians. Both HIV and the many opportunistic infections that manifest in patients due to their immunocompromised state also can affect the central nervous system (CNS). Thus, mental health clinicians need to be familiar with the diagnosis and management of HIV-related medical and psychiatric complications. This article provides an overview of the CNS-related manifestations resulting from HIV disease, including HIV-related dementia, psychotic disorders, delirium, CNS opportunistic infections and tumors, systemic abnormalities, psychoactive substances, and the adverse effects of certain medical treatments. Treatment strategies for individuals with HIV disease and comorbid severe mental illness are outlined and recommendations for future research are offered.
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PMID:Severe mental illness and HIV-related medical and neuropsychiatric sequelae. 916 Jan 79

We summarize the recommendations for research that emerged from a NIMH-sponsored Conference on HIV, AIDS, and Severe Mental Illness. Recommendations are made in four areas, namely, epidemiology of HIV infection, epidemiology of sexual and drug-use risk behaviors, risk reduction and transmission prevention, and treatment of infected persons. This research is urgently needed to adequately respond to the AIDS epidemic among people with severe mental illness.
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PMID:Research on HIV, AIDS, and severe mental illness: recommendations from the NIMH National Conference. 916 Jan 80

HIV+ subjects have shown impairment on tests of executive function including automatic attention and verbal tasks. Impairment of semantic priming in HIV patients would suggest a disruption of automatic semantic activation. We examined semantic priming in HIV+ individuals and HIV- control participants with no history of substance abuse, neurologic or psychiatric disorder unrelated to HIV. HIV+ participants were divided into cognitively normal and cognitively impaired subgroups on the basis of a neuropsychological battery of 15 tests. Participants were presented with English words and nonword letter strings and indicated if the stimulus was a word or nonword. The nonwords were orthographically and phonologically correct and were created by rearranging the letter sequence of words ("ulpit"). All words had an obvious antonym ("deep"); two-thirds were presented as sequential antonym pairs ("enter"-"exit"). There were no group differences in speed of response to nonwords, indicating no generalized reaction time deficit. While control and cognitively normal HIV+ participants showed an effect of priming on reaction time to correctly detected words, cognitively impaired HIV+ participants did not. The lack of semantic priming demonstrated by cognitively impaired HIV+ participants suggests that they have lessened activation of automatic semantic networks.
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PMID:Semantic priming impairment in HIV. 926 Apr 44


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