Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019625 (Rosai-Dorfman disease)
 763 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
SLC29A3 12.4
ZBTB46 12.1
CAPZA2 11.5
NOTCH1 protein 10.9
ARAF 10.4
CD1a 10.3
TNFRSF6 10.2
MAP2K2 9.2
CD68 9.2
Programmed cell death 1 9.1
S100 9.1
Langerin 9.0
caspase 10 9.0
MAP2K1 8.7
CCL23 8.6
PAX-5 8.5
MRP14 8.0
SLAM-associated protein 8.0
U2AF1 7.9
CD163 7.7
nodal 7.7
GCH 7.6
p41 7.3
cathepsin E 7.2
fascin 7.1
alpha1-antichymotrypsin 7.0
ERBB3 7.0
TRK 6.9
NTRK1 6.9
HS1 6.9
alpha-1-antichymotrypsin 6.8
B2M 6.7
OCT2 6.7
CD43 6.5
HS2 6.5
lacrimal 6.4
PGM1 6.3
CD79a 6.3
placental alkaline phosphatase 6.2
BRAF 6.2
ASXL1 6.1
GNAS 6.1
factor XIIIa 5.9
CD35 5.9
CD123 5.9
NF2 5.8
IGH 5.8
CD7 5.8
RDS 5.7
FDG 5.7
PEST 5.7
LMNA 5.7
PD-L2 5.7
CD21 5.7
M-protein 5.5
MPL 5.4
CD30 5.4
NF1 5.4
CCR6 5.3
panhypopituitarism 5.3
factor XII 5.3
CD1 5.2
CD99 5.2
LCA 5.2
AR protein 5.1
CD95 5.1
FAS 5.1
NOTCH1 5.0
ALK 5.0
ENT 5.0
CD20 4.9
PIK3CA 4.9
CD5 4.9
ESR 4.8
alpha-1-antitrypsin 4.7
LSD 4.7
CCL20 4.7
ERBB2 4.6
BTR 4.6
MAC 4.6
MIM 4.5
non-Hodgkin's lymphoma 4.5
protein S 4.5
RAF 4.4
T11 4.4
serum amyloid A 4.4
MDP 4.4
DIC 4.3
NRAS 4.3
lymphoid 4.3
lysozyme 4.3
SAGE 4.2
KRAS 4.2
NIDDM 4.2
ALA 4.2
CD57 4.1
IgG3 4.1
EMA 4.1
CD23 4.1
T12 4.1
WT1 4.1
Burkitt lymphoma 4.1
T10 4.1
MIP-1alpha 4.1
PGA 4.1
CCR7 4.1
MEK 4.0
Cyclin D1 4.0
rheumatoid factor 4.0
She 4.0
gamma-glutamyl transpeptidase 4.0
ACR 4.0
white cell 4.0
B19 3.9
ERG 3.9
CD117 3.8
PD-L1 3.8
MAP kinase 3.8
alpha 1-antitrypsin 3.8
VP2 3.8
TdT 3.8
interferon alpha 3.8
calretinin 3.7
CML 3.7
serum protein 3.7
Fas 3.7
BCL2 3.6
FAB 3.5
ECD 3.5
MRI 3.5
ERK 3.5
macrophage colony-stimulating factor 3.5
CD10 3.4
Ki-67 3.4
rhabdomyosarcoma 3.4
extracellular signal-regulated kinase 3.4
vitronectin 3.3
ALP 3.3
Raf-1 3.2
CD2 3.2
cathepsin D 3.2
cytokeratin 3.2
chemokine receptor 3.2
Del 3.0
mitogen-activated protein 3.0
hairy 2.9
JAK2 2.9
interferon-alpha 2.9
scratch 2.8
PRL 2.8
vimentin 2.7
COPD 2.7
PD-1 2.7
cyclin D1 2.7
HLA-DR 2.7
alpha, beta 2.7
CD31 2.7
androgen receptor 2.6
hormone receptor 2.6
smooth muscle actin 2.5
mast cell 2.5
AML 2.5
nuclear protein 2.4
CRP 2.4
zinc finger 2.4
MAPK 2.4
natriuretic peptide 2.4
p16 2.4
CD34 2.3
IL-1 beta 2.3
carcinoembryonic antigen 2.3
ferritin 2.3
ABC 2.2
thromboplastin 2.2
PTEN 2.2
CD45 2.2
adhesion molecule 2.2
CD11b 2.1
chymotrypsin 2.1
reserved 2.0
LDH 2.0
IL-5 2.0
IgA 2.0
T cell receptor 1.8
interleukin-6 1.8
acid phosphatase 1.8
C-reactive protein 1.8
CD8 1.7
proliferating cell nuclear antigen 1.7
thymus 1.7
esterase 1.5
osteosarcoma 1.5
TCR 1.5
CD4 1.5
interleukin-2 1.4
thyroid hormone 1.4
CO2 1.4
X-linked 1.3
IL-6 1.1
interferon 1.0
erythroid 1.0
IFN 0.9
AKT 0.9
PI3K 0.8
mTOR 0.7
TNF-alpha 0.7
prolactin 0.5
cytokine 0.5
tumor necrosis factor 0.5
membrane protein 0.5
hole 0.5
IgE 0.4
Bcl-2 0.3
olfactory 0.2
HLA 0.1
insulin -0.0
Sep -0.1
JAMA -0.4
glycoprotein -0.6
TNF -0.6
hemoglobin -0.6
Gen -0.6
Pol -0.7
collagen -1.6
Mol -2.3
Disease
Rosai-Dorfman disease 15.3
Sinus Histiocytosis 15.3
Non-Langerhans cell histiocytosis 13.8
Histiocytic neoplasms 13.3
LDHL 11.9
Erdheim-Chester disease 11.6
Dermatopathic lymphadenopathy 11.4
Mediastinal mass 11.3
reticulohistiocytoma 11.3
polyclonal hypergammaglobulinemia 10.5
xanthogranuloma 10.5
Jacksonian seizures 10.3
Reactive hemophagocytic syndrome 10.3
Baastrup 10.3
Dabska tumor 10.2
Chordoid glioma 10.2
reninoma 10.1
rhinoscleroma 10.0
lymphadenopathy 9.9
Langerhans cell histiocytosis 9.9
Mycobacterium kansasii infection 9.9
carcinoma of the trachea 9.6
Bartholin's cyst 9.5
TGCT 9.5
sigmoiditis 9.4
Bazin 9.1
phosphaturic mesenchymal tumor 9.0
pachymeningitis 8.8
Thyroid gland 8.8
autoimmune lymphoproliferative syndrome 8.7
dental abscess 8.5
xanthoma 8.3
hypergammaglobulinemia 8.3
Histiocytic sarcoma 8.3
Histiocytic necrotizing lymphadenitis 8.2
hypertropia 8.2
acquired toxoplasmosis 8.1
dysproteinemia 8.1
idiopathic disorder 8.0
angioimmunoblastic lymphadenopathy with dysproteinemia 8.0
Cavernous hemangioma 7.9
meningioma 7.9
colonic diverticulitis 7.8
hypertrichosis 7.7
testicular neoplasm 7.7
Castleman's disease 7.7
dacryoadenitis 7.7
hemophagocytic lymphohistiocytosis 7.6
generalized disease 7.6
Lhermitte-Duclos disease 7.5
collagenosis 7.5
hypoprothrombinemia 7.4
Pott's disease 7.4
Cat scratch disease 7.3
low-grade lymphomas 7.3
lymphadenitis 7.3
hemangiopericytoma 7.2
histiocytic lymphoma 7.2
xanthomatosis 7.2
marginal zone lymphoma 7.1
Ureteral obstruction 7.1
blood cancer 7.1
Meningioma 7.0
Meningioma 7.0
Orbit 6.9
Mikulicz 6.9
proptosis 6.9
autoimmune hemolytic anemia 6.9
gliosarcoma 6.8
chronic rhinitis 6.8
morphea 6.8
splenic marginal zone lymphoma 6.8
SIADH 6.8
thyroid mass 6.8
pseudogout 6.8
rare disease 6.7
Lymph node metastases 6.7
Lymph nodes 6.7
panniculitis 6.7
dermatofibroma 6.6
acute monocytic leukemia 6.6
histiocytoma 6.6
dacryocystitis 6.5
histiocytic lymphoma 6.5
mastopathy 6.4
gammopathy 6.4
xerophthalmia 6.4
anterior uveitis 6.4
rosacea 6.3
multicentric Castleman's disease 6.3
juvenile myelomonocytic leukemia 6.3
lymphomatoid granulomatosis 6.2
chronic suppurative otitis media 6.2
lipomatosis 6.2
acute chest syndrome 6.2
folliculitis 6.2
lymphoproliferative disorders 6.1
recurrent pneumonia 6.1
lymphoepithelioma 6.1
AA amyloidosis 6.0
Sjogren's syndrome 6.0
cheilitis 6.0
chronic myelomonocytic leukemia 5.9
chronic osteomyelitis 5.9
Whipple's disease 5.9
meninges 5.9
HMR 5.8
neoplastic process 5.8
pancreatic insufficiency 5.7
Neoplasms 5.7
siderosis 5.7
AMS 5.7
ileitis 5.6
panhypopituitarism 5.6
malignant fibrous histiocytoma 5.6
rind 5.6
intracranial tumors 5.6
osteosclerosis 5.6
hemangioblastoma 5.5
small lymphocytic lymphoma 5.5
quadriparesis 5.5
systemic disease 5.4
superior vena cava syndrome 5.4
Rosenthal 5.4
degenerative disc disease 5.4
trisomy 8 5.4
diplopia 5.4
autoimmune thyroiditis 5.4
RDS 5.4
dermatofibrosarcoma protuberans 5.3
hypersplenism 5.3
galactorrhea 5.3
dysphonia 5.3
hemosiderosis 5.3
acute pulmonary edema 5.3
plasmacytoma 5.2
tattoo 5.2
spondyloarthropathy 5.2
upper respiratory infection 5.2
sarcoidosis 5.2
epiphora 5.2
sialadenitis 5.2
lymphocytosis 5.2
lymphoma 5.1
sensory disturbance 5.1
Larynx 5.1
Larynx 5.1
Larynx 5.1
diabetes insipidus 5.1
T-cell lymphoma 5.1
IMT 5.1
lichen sclerosus 5.1
drug hypersensitivity 5.1
Larynx 5.1
paraplegia 5.0
galactorrhea 5.0
osteoporotic fracture 5.0
follicular lymphoma 5.0
spondylitis 4.9
xerostomia 4.9
pernicious anemia 4.9
schwannoma 4.9
carcinomatosis 4.8
spinal cord compression 4.8
autoimmune thyroid disease 4.8
sarcoma 4.8
postherpetic neuralgia 4.8
fibroma 4.7
Raynaud 4.7
pneumoconiosis 4.7
clear cell carcinoma 4.7
Hodgkin's disease 4.7
tonsillitis 4.7
Ewing's sarcoma 4.7
antiphospholipid syndrome 4.7
B-cell lymphoma 4.6
mastitis 4.6
tenosynovitis 4.6
hypogonadism 4.6
infectious mononucleosis 4.6
Wegener's granulomatosis 4.6
erythema nodosum 4.6
raised intracranial pressure 4.6
ameloblastoma 4.6
anaplastic large cell lymphoma 4.5
angiomyolipoma 4.5
silicosis 4.5
right heart failure 4.5
scotoma 4.5
hypersensitivity pneumonitis 4.5
phlebitis 4.5
hemolytic anemia 4.5
Nose 4.5
scleroderma 4.4
neurofibroma 4.4
non-Hodgkin's lymphoma 4.4
LCA 4.4
Niemann-Pick 4.4
FAS 4.4
polyarteritis nodosa 4.4
osteoma 4.3
diverticular disease 4.3
Q fever 4.2
lipodystrophy 4.2
optic atrophy 4.2
interstitial lung disease 4.1
pharyngitis 4.1
uveitis 4.1
lymphedema 4.1
brain tumor 4.1
essential thrombocythemia 4.1
Sweet 4.1
MRT 4.1
pericardial effusion 4.1
pancytopenia 4.1
T-cell acute lymphoblastic leukemia 4.1
EMA 4.1
herpes zoster 4.0
atrophic gastritis 4.0
radiculopathy 4.0
NF2 4.0
pericarditis 4.0
prostatic adenocarcinoma 4.0
bronchiolitis 4.0
cutaneous T-cell lymphoma 4.0
acne vulgaris 4.0
MAC 4.0
Epstein 4.0
T-cell lymphomas 4.0
goiter 3.9
seminoma 3.8
sinusitis 3.8
Gaucher disease 3.8
rhabdomyosarcoma 3.8
lupus 3.7
heart block 3.7
PGA 3.7
mycosis fungoides 3.7
hemangioma 3.7
lichen planus 3.6
endophthalmitis 3.6
polycythemia vera 3.6
deafness 3.6
polyarthritis 3.6
liposarcoma 3.6
carcinoid 3.6
toxoplasmosis 3.6
Syndrome 3.6
opportunistic infection 3.5
mucosa-associated lymphoid tissue 3.5
esophageal varices 3.5
anemia 3.5
lupus 3.5
hamartoma 3.5
myelofibrosis 3.5
B-cell lymphomas 3.4
agranulocytosis 3.4
facial palsy 3.4
Spleen 3.4
bacterial meningitis 3.4
lymphatic vessels 3.4
blindness 3.3
vasculitis 3.3
rash 3.3
dermatomyositis 3.3
confusion 3.3
benign tumor 3.3
bronchiectasis 3.2
genetic disorder 3.2
typhoid 3.2
lipoma 3.2
thymoma 3.2
pulmonary tuberculosis 3.1
ureter 3.1
leiomyosarcoma 3.1
systemic lupus erythematosus 3.1
polyposis 3.1
autoimmune disease 3.1
neoplastic transformation 3.1
uterine cervix 3.1
myelodysplastic syndrome 3.1
salmonellosis 3.1
renal cancer 3.1
nephrotic syndrome 3.1
myeloproliferative disorders 3.0
keratitis 3.0
hypercalcemia 3.0
leiomyoma 3.0
hypothyroidism 3.0
Crohn's disease 2.9
Pituitary 2.9
idiopathic pulmonary fibrosis 2.9
hydronephrosis 2.9
conjunctiva 2.9
adult respiratory distress syndrome 2.9
Fabry 2.9
osteomyelitis 2.9
parvovirus 2.8
sickle cell disease 2.8
plaque 2.8
amyloidosis 2.8
thrombocytopenia 2.8
interstitial pneumonia 2.8
Burkitt's lymphoma 2.8
skin disease 2.7
COPD 2.7
small cell lung cancer 2.7
idiopathic thrombocytopenic purpura 2.6
otitis media 2.6
aphasia 2.6
Thorax 2.6
pulmonary fibrosis 2.6
hydrocephalus 2.6
mesothelioma 2.5
chronic lymphocytic leukemia 2.5
multiple myeloma 2.5
pruritus 2.5
bone disease 2.5
solid tumor 2.5
immunodeficiency 2.4
pancreatitis 2.4
hematologic malignancies 2.3
residual disease 2.3
WT1 2.3
osteosarcoma 2.3
syphilis 2.3
tuberculosis 2.3
disseminated intravascular coagulation 2.3
melanoma 2.3
Kaposi's sarcoma 2.2
varicella 2.2
tumor 2.2
cytomegalovirus 2.1
carcinoma 2.1
arthritis 2.1
metastases 2.0
adenoma 2.0
pulmonary edema 2.0
chronic lymphocytic leukemia 1.9
dysplasia 1.9
Klebsiella 1.9
neuropathy 1.8
prolapse 1.8
subarachnoid hemorrhage 1.8
cornea 1.8
lung carcinoma 1.8
virus infection 1.8
Evans 1.8
acute renal failure 1.7
rheumatoid arthritis 1.7
dermatitis 1.6
STD 1.6
glomerulonephritis 1.5
respiratory failure 1.5
peritonitis 1.4
glioma 1.4
liver disease 1.4
dysphagia 1.4
coma 1.4
hyperlipidemia 1.4
renal failure 1.4
lung disease 1.3
bladder cancer 1.3
cancer 1.3
breast cancer 1.2
graft-versus-host disease 1.2
gastric cancer 1.2
pneumonia 1.2
chronic myeloid leukemia 1.1
chronic hepatitis 1.1
primary tumor 1.0
cardiomyopathy 1.0
cirrhosis 1.0
asthma 1.0
acute lymphoblastic leukemia 1.0
squamous cell carcinoma 0.9
cervical cancer 0.9
renal cell carcinoma 0.9
renal disease 0.9
proteinuria 0.8
congestive heart failure 0.8
HIV 0.8
diabetes 0.7
neuroblastoma 0.6
herpes simplex 0.6
colon cancer 0.5
hyperglycemia 0.5
chronic obstructive pulmonary disease 0.5
prostate cancer 0.5
cold 0.4
leukemia 0.4
fits 0.4
epilepsy 0.4
uterus 0.3
acute myeloid leukemia 0.2
heart failure 0.2
hepatitis B 0.1
multiple sclerosis -0.0
depression -0.5
tumorigenesis -0.5
type 2 diabetes -0.5
adenocarcinoma -0.7
hepatocellular carcinoma -0.8
lung cancer -0.8
infectious diseases -1.0
stroke -1.8
hypertension -2.0
Symptom
arm weakness 7.8
catarrh 7.8
giddiness 7.7
giddiness 7.7
night sweats 7.4
right lower quadrant pain 7.1
atypical chest pain 7.0
hepatosplenomegaly 6.8
abdominal fullness 6.7
tonic-clonic seizure 6.6
swollen joints 6.3
pleuritic chest pain 6.1
partial seizure 5.9
paraparesis 5.9
splenomegaly 5.5
hoarseness 5.4
dry skin 5.4
leg pain 5.4
blepharospasm 5.4
fever of unknown origin 5.3
shortness of breath 5.3
exertional dyspnea 5.2
hepatomegaly 5.2
pallor 5.0
numbness 5.0
ENT 5.0
ophthalmoplegia 4.6
acute abdominal pain 4.4
chronic cough 4.4
blurred vision 4.3
Ill 4.2
rhinorrhea 4.2
headache 4.2
facial pain 4.2
dry eye 4.0
knee pain 3.9
polyuria 3.8
dizziness 3.7
epigastric pain 3.6
vertigo 3.5
dysarthria 3.5
cough 3.4
back pain 3.4
dyspnea 3.2
weakness 3.1
paresthesia 3.1
ataxia 3.0
collapse 2.9
chest pain 2.9
hemoptysis 2.8
spasticity 2.7
tinnitus 2.7
arthralgia 2.5
spasm 2.5
seizures 2.4
syncope 2.2
constipation 2.0
abdominal pain 2.0
anorexia 1.6
vomiting 1.4
pain 1.3
fatigue 0.7
anesthesia -0.4
diarrhea -0.5
Drug
Clofarabine 8.2
Tocilizumab 6.6
Prednisolone 6.4
Methylprednisolone 5.5
ALA 4.9
ENT 4.3
Rituximab 3.9
Dermatol 2.8
ABC 2.2
Gel 1.5
Cardiovasc -0.3
Enzyme
SMP 5.9
TdT 4.5
lysozyme 4.3
MDP 4.0
MEK 3.5
cathepsin D 3.3
transglutaminase 3.1
mitogen-activated protein kinase 2.4
ERK 2.3
gamma-glutamyl transpeptidase 2.2
CD10 2.1
chymotrypsin 1.9
acid phosphatase 1.7
thromboplastin 1.7
focal adhesion kinase -0.1
Compound
Belt 7.1
Betamethasone 7.0
DHF 6.5
Nodular 6.5
Prednisolone 6.4
Methylprednisolone 5.6
Photodyn 5.3
Photodyn 5.3
Photodyn 5.3
Photodyn 5.3
Photodyn 5.3
Photodyn 5.3
Photodyn 5.3
Photodyn 5.3
Photodyn 5.3
Photodyn 5.3
Photodyn 5.3
Photodyn 5.2
PDT 4.8
LSD 4.6
T11 4.5
A 71 4.2
Lidocaine 4.2
T10 4.1
Dextran 4.1
MEK 4.0
Hematoxylin 4.0
DIC 4.0
A 42 3.8
VP-16 3.7
Rapamycin 3.6
A 3 3.5
ALP 3.3
PGA 3.2
Thyroid 3.0
PAS 2.7
His 1.9
Optimal 1.3
Clin 0.9
CO2 0.5
Dec 0.1
nitric oxide -0.2
TNF -0.6
cysteine -0.9
DNA -1.1
sulfate -1.4
glucose -1.9
Cardiol -2.5
sodium -2.7
calcium -3.0