Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019625 (
Rosai-Dorfman disease
)
763
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The production of
carcinoembryonic antigen
(
CEA
) by human breast cancer tissue has been studied in relation to the prognosis of 60 patients with breast cancer who were classified in Clinical Stage of UICC I, II and III, and who were treated by radical mastectomy. Tissue
CEA
was studied in primary tumors using an immunoperoxidase (PAP) method. The obtained results were as followings: 1) Patients who had
CEA
-negative tumors had significantly higher 10-year survival rates. 2) The positive staining rate of
CEA
rises as Clinical Stage and metastatic status of lymph nodes advanced. 3) There were significant correlations between staining rate of
CEA
and classification of histological type and differentiation. 4) There were significant correlations between staining rate of
CEA
and lymphoid infiltration around main tumor and
Sinus Histiocytosis
in regional lymph nodes. 5) These results suggest that immunohistological assessment of
CEA
in breast cancer tissue may provide more precise prognostic information.
...
PMID:[A clinicopathological study on carcinoembryonic antigen in breast cancer]. 237 Apr 34
