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Query: UMLS:C0019625 (Rosai-Dorfman disease)
 763 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This case report presents both the clinical and the histopathological features of the oldest patient on record with ophthalmic manifestations of Rosai-Dorfman Disease. An unusual feature, which has not been previously reported, is involvement of the cornea with subsequent perforation of the globe. The absence of lymphadenopathy is discussed.
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PMID:Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) with cutaneous and ocular involvement: a case report. 263 Mar 69

Sinus histiocytosis is a well-recognized condition that mainly affects children in the first decade of life. Although this usually benign disease often features massive cervical lymphadenopathy, numerous extranodal sites of involvement can be seen. We describe a new presenting manifestation for sinus histiocytosis. A 13-month-old infant developed a rapidly growing unilateral epibulbar tumor that involved the cornea. A complete physical examination revealed only mild inguinal lymphadenopathy. A diagnosis of sinus histiocytosis was made by histologic examination of the lesion after surgical excision.
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PMID:Sinus histiocytosis presenting as an epibulbar mass. A clinicopathologic case report. 317 54