Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019621 (
Langerhans cell histiocytosis
)
3,250
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
CD1a
338
Sep
216
BRAF
175
CD68
121
S100
120
MRI
97
She
88
Langerin
88
lymphoid
57
MAP2K1
41
cytokine
38
thymus
38
lysozyme
36
MAPK
35
CD1
35
MEK
33
FDG
31
ERK
31
HLA-DR
31
CD4
29
rhabdomyosarcoma
24
Pol
23
interferon
23
CD34
22
collagen
21
vasopressin
21
RAF
21
HLA
20
nodal
20
osteosarcoma
19
reserved
17
Mol
17
CD14
17
non-Hodgkin's lymphoma
16
panhypopituitarism
16
growth hormone
16
lectin
15
factor XIIIa
15
CD163
14
NRAS
13
extracellular signal-regulated kinase
13
CD8
13
Ki-67
12
IL-1
11
vimentin
11
Mal
11
p53
11
CD11c
11
IL-17
11
KRAS
10
ARAF
10
PHA
10
esterase
9
peroxidase
9
alkaline phosphatase
9
MAC
9
insulin
9
E-cadherin
9
ALL
8
TNF
8
CD2
8
CD11b
8
macrophage colony-stimulating factor
8
hairy
8
acid phosphatase
8
IFN
8
neurofibromatosis
8
CD31
7
fascin
7
CD20
7
tumor necrosis factor
7
lacrimal
7
androgen receptor
7
X-linked
7
proto-oncogene
7
CD56
7
PI3K
7
CD30
7
PIK3CA
7
CSF
7
more...
Disease
Langerhans cell histiocytosis
3250
tumor
371
cancer
313
diabetes insipidus
261
Erdheim-Chester disease
206
Letterer-Siwe disease
205
rare disease
153
sarcoidosis
126
xanthogranuloma
113
lymphoma
112
lymphadenopathy
104
Hodgkin's disease
80
Rosai-Dorfman disease
74
leukemia
74
interstitial lung disease
70
lung disease
68
pneumothorax
66
interstitial pneumonia
64
sarcoma
62
carcinoma
60
Juvenile xanthogranuloma
58
systemic disease
57
bronchiolitis
53
metastases
51
lymphangioleiomyomatosis
50
rash
50
idiopathic pulmonary fibrosis
50
emphysema
49
xanthoma
48
tuberculosis
48
pneumonia
47
neuroblastoma
40
Hand-Schuller-Christian disease
36
respiratory failure
33
pulmonary fibrosis
33
acute lymphoblastic leukemia
32
melanoma
32
Ewing's sarcoma
31
dysplasia
31
cholangitis
30
anemia
29
hypersensitivity pneumonitis
28
immunodeficiency
28
proptosis
27
acute myeloid leukemia
27
hemophagocytic lymphohistiocytosis
27
multiple myeloma
25
osteomyelitis
25
hypothyroidism
25
rhabdomyosarcoma
24
Hashimoto's thyroiditis
24
hemangioma
23
chronic obstructive pulmonary disease
23
pulmonary hypertension
23
osteosarcoma
23
histiocytoma
22
goiter
22
Langerhans cell sarcoma
21
Pulmonary Langerhans cell histiocytosis
21
liver disease
20
thrombocytopenia
20
non-Hodgkin's lymphoma
20
craniopharyngioma
19
amyloidosis
18
bronchiectasis
18
reticulohistiocytoma
17
lung cancer
17
seborrheic dermatitis
17
panhypopituitarism
17
rheumatoid arthritis
17
osteosclerosis
17
eosinophilia
17
Epstein
17
bone disease
16
chondrosarcoma
16
virus infection
15
otitis externa
15
diabetes
15
adenocarcinoma
15
hypopituitarism
14
more...
Symptom
pain
91
dyspnea
51
cough
49
polydipsia
41
headache
41
polyuria
38
hepatosplenomegaly
33
bone pain
24
seizures
19
ataxia
17
splenomegaly
17
hepatomegaly
17
diarrhea
14
weakness
13
respiratory distress
13
chest pain
12
anesthesia
12
erythema
11
back pain
11
abdominal pain
10
vomiting
10
fatigue
9
paraparesis
8
collapse
8
exertional dyspnea
8
ENT
7
tinnitus
7
vertigo
7
dysarthria
6
torticollis
6
Ill
6
knee pain
6
otalgia
6
neck pain
5
anorexia
5
nausea
5
hip pain
4
asthenia
4
dizziness
4
paresis
4
chills
4
cerebellar ataxia
4
non-productive cough
3
pallor
3
Darier's sign
3
hemoptysis
3
paresthesia
3
dental pain
3
tachypnea
3
generalized rash
3
tremor
3
fever of unknown origin
3
night sweats
3
chronic cough
3
numbness
3
lethargy
2
shortness of breath
2
leg pain
2
hoarseness
2
pleuritic chest pain
2
low back pain
2
constipation
2
arm weakness
2
stridor
2
ophthalmoplegia
2
penile lesion
2
halitosis
2
periorbital edema
2
productive cough
2
memory loss
2
orofacial pain
2
sciatica
2
nasal congestion
2
cachexia
2
dystonia
2
General symptoms
2
shoulder pain
2
snoring
1
Welt
1
apathy
1
more...
Drug
Dermatol
267
CSF
12
Etoposide
11
-deoxyadenosine
9
DDAVP
7
DDAVP
7
Cardiovasc
6
ENT
6
Paraffin
4
Velban
4
Leaf
4
Prednisone
4
IL-2
3
Prednisolone
3
NAG
2
SMP
2
Zoledronic acid
2
IFN-gamma
2
Zoledronic acid
2
Infliximab
1
Spiriva
1
Denosumab
1
Campath
1
AraC
1
Campath
1
MDS
1
Magnevist
1
Lenalidomide
1
ADM
1
ACT
1
Dial
1
Fluconazole
1
MAP
1
Teniposide
1
CIA
1
HCG
1
Adriamycin
1
CCL
1
Methotrexat
1
Methylprednisolone
1
Monit
1
Mutagen
1
Infliximab
1
TRM
1
Itraconazole
1
Imatinib
1
G-CSF
1
Secretin
1
Fluorescein
1
Frontal
1
Amifostine
1
ARA-C
1
HCH
1
Asthma
1
CAM
1
Indomethacin
1
lactose
1
Enzyme
mitogen-activated protein kinase
72
ERK
47
lysozyme
37
MEK
36
peroxidase
13
alkaline phosphatase
9
acid phosphatase
8
focal adhesion kinase
7
transglutaminase
6
protein kinase
6
MDP
6
ATPase
4
alpha-mannosidase
4
trypsin
4
tryptase
4
SMP
4
alanine aminotransferase
4
BAL
4
phosphodiesterase
3
protein kinase C
3
BMT
3
reverse transcriptase
3
lactate dehydrogenase
3
topoisomerase
2
cathepsin K
2
PGM
2
aspartate aminotransferase
2
chymotrypsin
2
topoisomerase
2
gamma-glutamyl transpeptidase
2
AST
1
phosphatidylinositol 3-kinase
1
STK11
1
CD13
1
CD10
1
RNA polymerase
1
MIP
1
adenosine deaminase
1
ACE
1
proteasome
1
phosphoglycerate kinase
1
catalase
1
catechol 1,2-dioxygenase
1
ADH
1
neuraminidase
1
cathepsin D
1
MMP
1
CPT
1
ACS
1
phosphoinositide 3-kinase
1
alpha-galactosidase
1
urokinase-type plasminogen activator
1
TdT
1
glutathione peroxidase
1
PARP
1
phospholipase C
1
collagenase
1
prostaglandin synthetase
1
acetyl-CoA carboxylase
1
cdc2
1
alcohol dehydrogenase
1
CPT
1
MAP
1
CPT
1
beta-glucuronidase
1
adenosine deaminase
1
luciferase
1
creatine kinase
1
cathepsin B
1
MEKK1
1
botulinum neurotoxin
1
lipase
1
granzyme B
1
cellulase
1
Compound
Clin
290
Dec
206
DNA
54
MEK
32
His
23
leucine
21
VP-16
21
water
21
nitrogen
15
oxygen
15
methane
14
glucose
13
galactose
12
sodium
11
Thyroid
11
A 3
11
iron
9
acetate
9
Vinblastine
8
fluorine
8
TNF
8
CO2
8
Optimal
7
A 42
6
Prednisone
6
TSH
5
formaldehyde
5
potassium
5
ethanol
5
Letter
5
Neo
5
DTPA
5
calcium
4
BAL
4
ACTH
4
DBA
4
DBA
4
Belt
4
urea
4
hydrogen
4
nitric oxide
4
PNA
4
Cardiol
4
PAS
4
CDA
4
6-12
4
DBA
4
zinc
4
TRH
3
formaldehyde
3
sulfate
3
Ara-C
3
prostacyclin
3
arginine
3
Ara-C
3
retinoic acid
3
acetic acid
3
creatinine
3
Prednisolone
3
iodine
3
L-DOPA
2
BCG
2
Hematoxylin
2
MTX
2
hydroxide
2
N-acetyl-D-glucosamine
2
Thyroxine
2
PEA
2
Methotrexate
2
A 1
2
serine
2
glutamic acid
2
valine
2
carbonate
2
cAMP
2
Coronal
2
barium
2
GalNAc
2
PGE2
2
TBI
2
more...