Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019621 (Langerhans cell histiocytosis)
 3,250 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
FAM73A 13.3
IGG4 13.3
CD1a molecule 11.4
ARAF 10.7
PLEKHA6 10.7
CD1a 10.5
Langerin 10.4
non-specific cross reacting antigen 10.3
ZBTB46 10.0
IGK@ 9.9
CD1A 9.9
MAP2K1 9.7
EV2 9.7
CAPZA2 9.5
HLA-DQB2 9.4
MYM 9.3
HLA class I A 9.0
NOTCH1 protein 8.8
CCNB3 8.7
80kD 8.7
PACSIN2 8.4
LH-2 8.4
Mulibrey nanism 8.2
Tumor protein p53 8.2
MAP2K2 8.1
MLT1 8.1
monocarboxylate transporter 2 8.1
Mast cell tryptase 8.0
TRIM37 8.0
BDCA1 7.9
EV1 7.9
factor XIIIa 7.8
CD68 7.7
S100 7.6
DRC1 7.6
IGH@ 7.6
interferon alpha A 7.6
ZNF198 7.5
CD100 7.5
BRAF 7.5
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Disease
Langerhans cell histiocytosis 13.3
Acquired hemoglobinopathy 13.3
Letterer-Siwe disease 12.9
Hand-Schuller-Christian disease 12.9
Congenital self-healing histiocytosis 12.7
Non-Langerhans cell histiocytosis 12.7
Pulmonary Langerhans cell histiocytosis 12.3
reticulum cell lymphoma 12.3
Erdheim-Chester disease 12.0
Benign cephalic histiocytosis 11.9
Eosinophilic granuloma of bone 11.8
Langerhans cell sarcoma 11.7
Juvenile xanthogranuloma 11.7
Generalized eruptive histiocytoma 11.7
Dendritic cell sarcoma 11.7
reticulohistiocytoma 11.7
Pulmonary eosinophilic granuloma 11.7
Xanthoma disseminatum 11.5
sinus polyp 11.3
Histiocytic neoplasms 11.3
Reticulohistiocytosis 11.3
RB-ILD 11.3
Ewing's sarcoma metastatic 10.9
dermoid inclusion 10.9
Respiratory bronchiolitis-associated interstitial lung disease 10.8
xanthogranuloma 10.7
Sinus Histiocytosis 10.7
Dermatopathic lymphadenopathy 10.4
Frosted branch angiitis 10.3
hepatalgia 10.3
CNS germinoma 10.0
JPD 9.9
Rosai-Dorfman disease 9.9
CNS degenerative disease 9.8
Lymphohistiocytosis 9.8
malignant giant cell tumor of bone 9.7
Canine cutaneous histiocytoma 9.7
Leiner's disease 9.6
Keratosis obturans 9.6
diabetes insipidus 9.5
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Symptom
Darier's sign 9.2
General symptoms 8.4
penile lesion 8.1
Radicular pain 7.8
generalized rash 7.7
polydipsia 7.5
thoracic back pain 7.5
otorrhagia 7.2
polyuria 6.9
arm weakness 6.7
non-productive cough 6.7
growing pains 6.6
periorbital edema 6.3
bone pain 6.2
hepatosplenomegaly 6.2
otalgia 5.9
jaw pain 5.7
adipsia 5.7
postnasal drip 5.2
torticollis 5.2
pleuritic chest pain 5.1
halitosis 5.0
hepatomegaly 4.8
paraparesis 4.8
night sweats 4.6
dental pain 4.6
exertional dyspnea 4.5
hip pain 4.4
orthopnea 4.4
Halo 4.4
knee pain 4.4
orofacial pain 4.4
cough 4.3
ankle pain 4.2
clumsiness 4.2
dyspnea 4.2
ataxic gait 4.2
productive cough 4.1
nasal congestion 4.1
splenomegaly 4.1
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Drug
Velban 9.0
Methotrexat 8.2
Spiriva 8.2
Teniposide 6.7
Etoposide 6.6
DDAVP 6.2
DDAVP 6.1
SMP 5.7
-deoxyadenosine 5.4
ARA-C 5.4
Magnevist 5.3
Zoledronic acid 5.3
Prednisone 5.3
Amifostine 4.7
TRM 4.7
Zoledronic acid 4.6
Prednisolone 4.3
Paraffin 4.2
Denosumab 4.2
Lenalidomide 3.9
Secretin 3.7
Campath 3.7
Campath 3.7
CIA 3.6
Methylprednisolone 3.4
Dermatol 3.3
AraC 3.2
NAG 3.2
Infliximab 3.1
Infliximab 3.1
CCL 2.9
Fluconazole 2.9
ENT 2.8
Itraconazole 2.3
Frontal 2.2
ACT 2.2
MDS 2.1
Imatinib 2.0
CSF 1.9
HCG 1.9
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Enzyme
SMP 5.8
alpha-mannosidase 4.7
catechol 1,2-dioxygenase 4.7
MDP 4.4
STK11 4.4
BAL 4.3
MEK 4.3
lysozyme 4.1
tryptase 3.8
PGM 3.8
transglutaminase 3.6
BMT 3.5
cathepsin K 3.4
mitogen-activated protein kinase 2.9
acid phosphatase 2.6
alpha-galactosidase 2.5
prostaglandin synthetase 2.4
MEKK1 2.4
TdT 2.4
botulinum neurotoxin 2.4
ERK 2.3
phosphoglycerate kinase 2.2
ADH 2.1
acetyl-CoA carboxylase 1.8
CPT 1.6
granzyme B 1.6
CPT 1.5
CD13 1.4
cathepsin D 1.2
cathepsin B 1.2
MMP 1.2
gamma-glutamyl transpeptidase 1.1
CPT 1.1
topoisomerase 1.1
MIP 1.0
topoisomerase 1.0
peroxidase 1.0
adenosine deaminase 0.9
adenosine deaminase 0.9
alkaline phosphatase 0.9
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Compound
1,3-dithiolane-2-thione 11.7
Dioxolane 7.7
1,3-dithiolane 7.5
NHD 7.1
CONV 7.1
Vinblastine 7.0
VP-16 6.0
DBB 6.0
Triamcinolone acetonide 5.4
CDA 5.4
Pamidronate 5.2
Prednisone 5.2
Belt 5.1
STP 5.0
Amifostine 4.7
MEK 4.6
6-Mercaptopurine 4.6
VLA 4.5
DHF 4.4
A 42 4.3
Prednisolone 4.3
AME 4.2
Ara-C 4.2
Coronal 4.1
Toluidine blue 4.0
PNA 4.0
Etanercept 4.0
Neo 3.9
PEA 3.9
Vinca 3.9
BAL 3.8
A 3 3.8
Ara-C 3.8
Thyroxine 3.7
Secretin 3.7
Cytochalasin B 3.6
Methylprednisolone 3.5
VM-26 3.5
EDC 3.4
Nodular 3.4
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