Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
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Compound
Query: UMLS:C0019621 (
Langerhans cell histiocytosis
)
3,250
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We report on a 5-year 8-month-old boy suffering from spinal
Langerhans cell histiocytosis
(
LCH
), who had initial symptoms of back and abdominal pain, as well as tilting of the shoulder that mimicked hemivertebra of
T10
with scoliosis, as revealed by radiography. The
LCH
-involved vertebra did not demonstrate the classic radiographic picture of vertebra plana until the vertebral body symmetrically collapsed about 6 months later, when the patient's scoliosis disappeared. The delayed diagnosis of
LCH
was confirmed by biopsy after another 6 months. Polyostotic lesions affecting C6, T5, T9-12, and L2 were found. This case represented an unusual presentation of
LCH
as an early disease entity, which resulted in a misdiagnosis of painful scoliosis. We believe we are the first to report
LCH
as a differential diagnosis of painful scoliosis.
...
PMID:Langerhans cell histiocytosis as a possible differential diagnosis of painful scoliosis. 1758 23
