Gene/Protein
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Compound
Pivot Concepts:
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Target Concepts:
Gene/Protein
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Query: UMLS:C0019621 (
Langerhans cell histiocytosis
)
3,250
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Langerhans' cell histiocytosis
(
LCH
) encompasses a group of disorders with variable clinical features and prognosis that share in common the infiltration of involved tissues by numerous Langerhans' cell (LC), often organized in granulomas. In adults, pulmonary involvement with
LCH
is observed predominantly in young cigarette smokers. Lung involvement is usually an isolated or a predominant manifestation, and is characterized by LC granulomas entered on distal bronchioles. HRCT has proved to be very useful in the diagnosis of pulmonary
LCT
, showing in typical asess the association of nodules, cavitary nodules and cystic lesions with both thick and thin walls. The definite diagnosis of pulmonary
LCT
generally requires lung biopsy. The pathogenesis of pulmonary
LCH
is not well understood.
...
PMID:[Etiology, diagnosis, and treatment of pulmonary histiocytosis]. 1470 15
