Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019621 (Langerhans cell histiocytosis)
 3,250 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 27-year-old woman with known pulmonary, cutaneous and osseous histiocytosis X presented with vague abdominal pain. Double-contrast barium enema examination revealed multiple colonic bull's-eye lesions. Biopsy showed histiocytic infiltration similar to that already described at other sites in this patient (the lungs and bone). To the authors' knowledge, this case represents the first radiologic description of this manifestation of histiocytosis X. Though rare, it should be considered in the differential diagnosis of colonic bull's-eye lesions.
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PMID:Colonic bull's-eye lesions in histiocytosis X. 798 13

Gastrointestinal (GI) tract involvement in Langerhans cell histiocytosis is probably not uncommon [1,2], but reports of radiologic findings have been limited to the small intestine and mesenteric lymph nodes [3-5]. We report a 16-month-old child with known Langerhans cell histiocytosis, who was found to have mucosal irregularities of the colon as seen on air contrast barium enema, and was subsequently found to have diffuse involvement of the colon histologically confirmed by multiple biopsies.
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PMID:Barium enema findings in a case of Langerhans cell histiocytosis involving the colon. 815 70