Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019621 (
Langerhans cell histiocytosis
)
3,250
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Langerhans cell histiocytosis
(
LCH
) is a rare disorder in adults which usually manifests with involvement of multiple organ systems, including the central nervous system. We describe an unusual case of biopsy-proven
LCH
presenting with frontotemporal-dominant
cognitive impairment
with hypothalamic involvement, along with multisystem disease. We propose that the dementia was probably an immune-mediated process triggered by
LCH
which responded dramatically to high-dose steroids.
...
PMID:Langerhans cell histiocytosis presenting as a rapidly evolving frontotemporal syndrome. 3063 89
